7215284
Phospho-SHP-1 (Tyr536) Recombinant Rabbit Monoclonal Antibody (Shp1Y536-2A7), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Phospho-SHP-1 (Tyr536)
Concentration
0.5 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Alias
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Gene Symbols
PTPN6
Isotype
IgG κ
Purification Method
Protein A/G
Product Type
Antibody
Clone
Shp1Y536-2A7
Applications
Flow Cytometry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P29350
Gene ID (Entrez)
5777
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
PTPN6
Related Products
Description
- SHP-1 (PTPN6) is a non-receptor protein tyrosine phosphatase that is expressed primarily in hematopoietic cells
- The enzyme is composed of two SH2 domains, a tyrosine phosphatase catalytic domain, and a carboxy-terminal regulatory domain
- SHP-1 removes phosphates from target proteins to downregulate several tyrosine kinase-regulated pathways
- In hematopoietic cells, the amino-terminal SH2 domain of SHP-1 binds to tyrosine phosphorylated erythropoietin receptors (EpoR) to negatively regulate hematopoietic growth
- Overexpression of SHP-1 in epithelial cells results in dephosphorylation of the Ros receptor tyrosine kinase and subsequent downregulation of Ros-dependent cell proliferation and transformation
- Following ligand binding in myeloid cells, SHP-1 associates with the IL-3R beta chain and downregulates IL-3-induced tyrosine phosphorylation and cell proliferation.
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Antigen: Phospho-SHP-1 (Tyr536)
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Alias: 70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Gene Symbols: PTPN6
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Clone: Shp1Y536-2A7
Applications: Flow Cytometry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P29350
Gene ID (Entrez): 5777
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: PTPN6
Antigen:
Phospho-SHP-1 (Tyr536)
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Gene Symbols:
PTPN6
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Clone:
Shp1Y536-2A7
Applications:
Flow Cytometry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P29350
Gene ID (Entrez):
5777
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.
Primary or Secondary:
Primary
Content And Storage:
-20°C
Gene:
PTPN6
Antigen: Phospho-PTEN (Ser380)
Concentration: __
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: 10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Gene Symbols: PTEN
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Clone: PTENS380-NA9
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: O08586, P60484
Gene ID (Entrez): 19211, 5728
Immunogen: A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark
Gene: PTEN
Antigen:
Phospho-PTEN (Ser380)
Concentration:
__
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Gene Symbols:
PTEN
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Clone:
PTENS380-NA9
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
O08586, P60484
Gene ID (Entrez):
19211, 5728
Immunogen:
A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark
Gene:
PTEN
Antigen: Phospho-Stat3 (Tyr705)
Concentration: __
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: 1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Gene Symbols: STAT3
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Clone: Stat3Y705-B12
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P40763, P42227
Gene ID (Entrez): 20848, 6774
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr705 of human phospho Stat3.
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark
Gene: STAT3
Antigen:
Phospho-Stat3 (Tyr705)
Concentration:
__
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Gene Symbols:
STAT3
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Clone:
Stat3Y705-B12
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P40763, P42227
Gene ID (Entrez):
20848, 6774
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr705 of human phospho Stat3.
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark
Gene:
STAT3
Antigen: Phospho-Stat3 (Tyr705)
Concentration: __
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: 1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Gene Symbols: STAT3
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Clone: Stat3Y705-B12
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P40763, P42227
Gene ID (Entrez): 20848, 6774
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr705 of human phospho Stat3.
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark
Gene: STAT3
Antigen:
Phospho-Stat3 (Tyr705)
Concentration:
__
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Gene Symbols:
STAT3
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Clone:
Stat3Y705-B12
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P40763, P42227
Gene ID (Entrez):
20848, 6774
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr705 of human phospho Stat3.
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark
Gene:
STAT3