7215285
Phospho-PTEN (Ser380) Recombinant Rabbit Monoclonal Antibody (PTENS380-NA9), FITC, Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Phospho-PTEN (Ser380)
Applications
Flow Cytometry
Conjugate
FITC
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
O08586, P60484
Gene ID (Entrez)
19211, 5728
Immunogen
A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.
Primary or Secondary
Primary
Content And Storage
4° C, store in dark
Gene
PTEN
Clone
PTENS380-NA9
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Gene Symbols
PTEN
Isotype
IgG κ
Purification Method
Protein A/G
Product Type
Antibody
Related Products
Description
- PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency
- The PTEN gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase
- It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases
- Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates
- PTEN negatively regulates intracellular levels of phosphatidylinositol-3, 4, 5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway
- PTEN plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation
- Also, PTEN may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue
- The nuclear monoubiquitinated form possesses greater apoptotic potential, whereas the cytoplasmic nonubiquitinated form of PTEN induces less tumor suppressive ability.
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Antigen: Phospho-PTEN (Ser380)
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: O08586, P60484
Gene ID (Entrez): 19211, 5728
Immunogen: A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark
Gene: PTEN
Clone: PTENS380-NA9
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: 10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Gene Symbols: PTEN
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Phospho-PTEN (Ser380)
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
O08586, P60484
Gene ID (Entrez):
19211, 5728
Immunogen:
A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark
Gene:
PTEN
Clone:
PTENS380-NA9
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Gene Symbols:
PTEN
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Antigen: Phospho-Stat3 (Tyr705)
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P40763, P42227
Gene ID (Entrez): 20848, 6774
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr705 of human phospho Stat3.
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark
Gene: STAT3
Clone: Stat3Y705-B12
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: 1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Gene Symbols: STAT3
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Phospho-Stat3 (Tyr705)
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P40763, P42227
Gene ID (Entrez):
20848, 6774
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr705 of human phospho Stat3.
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark
Gene:
STAT3
Clone:
Stat3Y705-B12
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Gene Symbols:
STAT3
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Antigen: Phospho-Stat3 (Tyr705)
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P40763, P42227
Gene ID (Entrez): 20848, 6774
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr705 of human phospho Stat3.
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark
Gene: STAT3
Clone: Stat3Y705-B12
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: 1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Gene Symbols: STAT3
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Phospho-Stat3 (Tyr705)
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P40763, P42227
Gene ID (Entrez):
20848, 6774
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr705 of human phospho Stat3.
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark
Gene:
STAT3
Clone:
Stat3Y705-B12
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Gene Symbols:
STAT3
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Antigen: Phospho-PTEN (Ser380, Thr382, Thr383)
Applications: Flow Cytometry, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: O08586, P60484
Gene ID (Entrez): 19211, 5728
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: PTEN
Clone: PTENS380T382383-E4
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Alias: 10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Gene Symbols: PTEN
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Phospho-PTEN (Ser380, Thr382, Thr383)
Applications:
Flow Cytometry, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
O08586, P60484
Gene ID (Entrez):
19211, 5728
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.
Primary or Secondary:
Primary
Content And Storage:
-20°C
Gene:
PTEN
Clone:
PTENS380T382383-E4
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Gene Symbols:
PTEN
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody