7215288
Phospho-PTEN (Ser380, Thr382, Thr383) Recombinant Rabbit Monoclonal Antibody (PTENS380T382383-E4), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Phospho-PTEN (Ser380, Thr382, Thr383)
Concentration
0.5 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Alias
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Gene Symbols
PTEN
Isotype
IgG κ
Purification Method
Protein A/G
Product Type
Antibody
Clone
PTENS380T382383-E4
Applications
Flow Cytometry, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
O08586, P60484
Gene ID (Entrez)
19211, 5728
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
PTEN
Related Products
Description
- PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency
- The PTEN gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase
- It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases
- Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates
- PTEN negatively regulates intracellular levels of phosphatidylinositol-3, 4, 5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway
- PTEN plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation
- Also, PTEN may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue
- The nuclear monoubiquitinated form possesses greater apoptotic potential, whereas the cytoplasmic nonubiquitinated form of PTEN induces less tumor suppressive ability.
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Antigen: Phospho-PTEN (Ser380, Thr382, Thr383)
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Alias: 10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Gene Symbols: PTEN
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Clone: PTENS380T382383-E4
Applications: Flow Cytometry, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: O08586, P60484
Gene ID (Entrez): 19211, 5728
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: PTEN
Antigen:
Phospho-PTEN (Ser380, Thr382, Thr383)
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Gene Symbols:
PTEN
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Clone:
PTENS380T382383-E4
Applications:
Flow Cytometry, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
O08586, P60484
Gene ID (Entrez):
19211, 5728
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.
Primary or Secondary:
Primary
Content And Storage:
-20°C
Gene:
PTEN
Antigen: Phospho-Lamin A/C (Ser22)
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Alias: 70 kDa lamin; cb948; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; lamin; lamin A; lamin A/C; lamin A/C L homeolog; lamin A/C-like 1; Lamin A+C mutant; Lamin AC; lamin a-c; lamin C; lamin C2; lamin-A; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; lmna; LMNA protein; lmna.L; lmna-A; LMNC; LMNL1; mutant 453W; Mutant lamin A/C; nuclear intermediate filament protein; nuclear lamin A; prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32; RP11-54H19.1; unnamed protein product; wu:fk66d12; XELAEV_18040808mg
Gene Symbols: LMNA
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Clone: LaminACS22-CF12
Applications: Flow Cytometry, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P02545, P48678
Gene ID (Entrez): 16905, 4000
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser22 of human phospho Lamin A/C.
Primary or Secondary: Primary
Content And Storage: -20°C
Gene: LMNA
Antigen:
Phospho-Lamin A/C (Ser22)
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Alias:
70 kDa lamin; cb948; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; lamin; lamin A; lamin A/C; lamin A/C L homeolog; lamin A/C-like 1; Lamin A+C mutant; Lamin AC; lamin a-c; lamin C; lamin C2; lamin-A; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; lmna; LMNA protein; lmna.L; lmna-A; LMNC; LMNL1; mutant 453W; Mutant lamin A/C; nuclear intermediate filament protein; nuclear lamin A; prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32; RP11-54H19.1; unnamed protein product; wu:fk66d12; XELAEV_18040808mg
Gene Symbols:
LMNA
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Clone:
LaminACS22-CF12
Applications:
Flow Cytometry, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P02545, P48678
Gene ID (Entrez):
16905, 4000
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser22 of human phospho Lamin A/C.
Primary or Secondary:
Primary
Content And Storage:
-20°C
Gene:
LMNA
Antigen: Phospho-CrkL (Tyr207)
Concentration: __
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: 1110025F07Rik; AA589403; AI325100; CRK like proto-oncogene, adaptor protein; CRKL; crkl {ECO:0000312; crk-like protein; crk-like protein {ECO:0000250; Crkol; EMBL:AAH85865.1, ECO:0000312; OTTHUMP00000198539; RGD:1308531}; UniProtKB:P46109}; v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk sarcoma virus CT10 oncogene homolog-like
Gene Symbols: CRKL
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Clone: CrkLY207-G4
Applications: Flow Cytometry
Conjugate: APC
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P46109, P47941
Gene ID (Entrez): 12929, 1399
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr207 of human phospho CrkL.
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: CRKL
Antigen:
Phospho-CrkL (Tyr207)
Concentration:
__
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
1110025F07Rik; AA589403; AI325100; CRK like proto-oncogene, adaptor protein; CRKL; crkl {ECO:0000312; crk-like protein; crk-like protein {ECO:0000250; Crkol; EMBL:AAH85865.1, ECO:0000312; OTTHUMP00000198539; RGD:1308531}; UniProtKB:P46109}; v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk sarcoma virus CT10 oncogene homolog-like
Gene Symbols:
CRKL
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Clone:
CrkLY207-G4
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P46109, P47941
Gene ID (Entrez):
12929, 1399
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr207 of human phospho CrkL.
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
CRKL
Antigen: Phospho-CrkL (Tyr207)
Concentration: __
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: 1110025F07Rik; AA589403; AI325100; CRK like proto-oncogene, adaptor protein; CRKL; crkl {ECO:0000312; crk-like protein; crk-like protein {ECO:0000250; Crkol; EMBL:AAH85865.1, ECO:0000312; OTTHUMP00000198539; RGD:1308531}; UniProtKB:P46109}; v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk sarcoma virus CT10 oncogene homolog-like
Gene Symbols: CRKL
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Clone: CrkLY207-G4
Applications: Flow Cytometry
Conjugate: APC
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P46109, P47941
Gene ID (Entrez): 12929, 1399
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr207 of human phospho CrkL.
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: CRKL
Antigen:
Phospho-CrkL (Tyr207)
Concentration:
__
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
1110025F07Rik; AA589403; AI325100; CRK like proto-oncogene, adaptor protein; CRKL; crkl {ECO:0000312; crk-like protein; crk-like protein {ECO:0000250; Crkol; EMBL:AAH85865.1, ECO:0000312; OTTHUMP00000198539; RGD:1308531}; UniProtKB:P46109}; v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk sarcoma virus CT10 oncogene homolog-like
Gene Symbols:
CRKL
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Clone:
CrkLY207-G4
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P46109, P47941
Gene ID (Entrez):
12929, 1399
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr207 of human phospho CrkL.
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
CRKL