PIMA537274

Phospho-PTEN (Ser380, Thr382, Thr383) Recombinant Rabbit Monoclonal Antibody (PTENS380T382383-E4), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA537274-Each-of-1 In Stock ₹ 31,742.76

PIMA537274 - Each of 1

₹ 31,742.76

In Stock

Quantity

1

Base Price: ₹ 31,742.76

GST (18%): ₹ 5,713.697

Total Price: ₹ 37,456.457

Antigen

Phospho-PTEN (Ser380, Thr382, Thr383)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

O08586, P60484

Gene Symbols

PTEN

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG κ

Applications

Flow Cytometry, Western Blot

Clone

PTENS380T382383-E4

Conjugate

Unconjugated

Gene

PTEN

Gene Alias

10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

19211, 5728

Content And Storage

-20°C

Form

Liquid

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Description

  • PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency
  • The PTEN gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase
  • It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases
  • Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates
  • PTEN negatively regulates intracellular levels of phosphatidylinositol-3, 4, 5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway
  • PTEN plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation
  • Also, PTEN may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue
  • The nuclear monoubiquitinated form possesses greater apoptotic potential, whereas the cytoplasmic nonubiquitinated form of PTEN induces less tumor suppressive ability.

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Img

Fischer Scientific

PIMA537274

--


Antigen:
Phospho-PTEN (Ser380, Thr382, Thr383)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O08586, P60484

Gene Symbols:
PTEN

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry, Western Blot

Clone:
PTENS380T382383-E4

Conjugate:
Unconjugated

Gene:
PTEN

Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
19211, 5728

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

PIMA537275

--


Antigen:
Phospho-PTEN (Ser380, Thr382, Thr383)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
O08586, P60484

Gene Symbols:
PTEN

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.

Quantity:
10 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
PTENS380T382383-E4

Conjugate:
PE

Gene:
PTEN

Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
19211, 5728

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

PIMA537276

--


Antigen:
Phospho-PTEN (Ser380, Thr382, Thr383)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
O08586, P60484

Gene Symbols:
PTEN

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.

Quantity:
10 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
PTENS380T382383-E4

Conjugate:
FITC

Gene:
PTEN

Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
19211, 5728

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Fischer Scientific

PIMA537277

--


Antigen:
Phospho-PTEN (Ser380, Thr382, Thr383)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
O08586, P60484

Gene Symbols:
PTEN

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.

Quantity:
10 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
PTENS380T382383-E4

Conjugate:
APC

Gene:
PTEN

Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
19211, 5728

Content And Storage:
4° C

Form:
Liquid