7215265

Phospho-PLCg2 (Tyr759) Recombinant Rabbit Monoclonal Antibody (PLCG2Y759-G3), PE, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-PLCg2 (Tyr759)

Applications

Flow Cytometry

Conjugate

PE

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

P16885, Q8CIH5

Gene ID (Entrez)

234779, 5336

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr759 of human phospho PLCg2.

Primary or Secondary

Primary

Content And Storage

4° C

Gene

Plcg2

Clone

PLCG2Y759-G3

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV

Gene Symbols

Plcg2

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

Related Products

Img

Fischer Scientific

PIMA537233

--

Img

Fischer Scientific

7215145

Rabbit Recombinant Monoclonal Antib...

Img

Fischer Scientific

7215152

Rabbit Recombinant Monoclonal Antib...

Img

Fischer Scientific

7215285

Rabbit Recombinant Monoclonal Antib...

Img

Fischer Scientific

PIMA537314

--

Img

Fischer Scientific

PIMA537052

--

Img

Fischer Scientific

7215284

Rabbit Recombinant Monoclonal Antib...

Img

Fischer Scientific

7215249

Rabbit Recombinant Monoclonal Antib...

Description

  • Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate
  • There are many mammalian PLC isozymes, including PLC beta1, PLC beta2, PLC beta3, PLC beta4, PLC gamma1, PLC gamma2, PLC delta1, PLC delta2 and PLCe
  • PLC delta exists as four different isoforms
  • PLC delta1, a calcium signal amplifier, is activated by an atypical GTP-binding protein
  • In addition, PLC delta1 is an effector for GTP-binding protein transglutaminase II-mediated oxytocin receptor and alpha1B-adrenoreceptor signaling
  • Mouse PLC delta1 is highly expressed in brain, heart, lung and testis
  • PLC delta is abnormally accumulated in autopsied brains with Alzheimer's disease (AD), suggesting that it may play a role in the pathology of AD
  • PLC delta2 is markedly expressed in type II intestinal metaplasia and in the adenocarcinoma
  • When PLC delta2 is expressed in type I intestinal metaplasia, the metaplasia is generally considered benignant, yet evolves toward neoplastic transformation
  • Thus, PLC delta2 expression may be a possible marker of gastric malignant transformation.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7215265

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-PLCg2 (Tyr759)

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P16885, Q8CIH5

Gene ID (Entrez):
234779, 5336

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr759 of human phospho PLCg2.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Plcg2

Clone:
PLCG2Y759-G3

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV

Gene Symbols:
Plcg2

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215266

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-HCLS1 (Tyr397)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P14317, P49710

Gene ID (Entrez):
15163, 3059

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr397 of human phospho HS1.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
HCLS1

Clone:
HS1Y397-F12

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
AW213261; CTTNL; HCLS1; hematopoietic cell specific Lyn substrate 1; hematopoietic cell-specific Lyn substrate 1; Hematopoietic lineage cell-specific protein; HS1; LckBP1; p75

Gene Symbols:
HCLS1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215268

Rabbit Recombinant Monoclonal Antib...


Antigen:
SARS-CoV-2 Nucleocapsid

Applications:
ELISA

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Virus

Gene Accession No.:
P0DTC9

Gene ID (Entrez):
43740575

Immunogen:
SARS-CoV-2 nucleoprotein (NP) specific peptide.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
N

Clone:
84C4A

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.02% sodium azide

Gene Alias:
COVID19 Nucleocapsid, COVID-19 nucleocapsid, COVID19 Spike nucleocapsid, SARS-CoV-2 N

Gene Symbols:
N

Isotype:
IgG1 κ

Purification Method:
Protein A

Product Type:
Antibody

Img

Fischer Scientific

7215268

Rabbit Recombinant Monoclonal Antib...


Antigen:
SARS-CoV-2 Nucleocapsid

Applications:
ELISA

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Virus

Gene Accession No.:
P0DTC9

Gene ID (Entrez):
43740575

Immunogen:
SARS-CoV-2 nucleoprotein (NP) specific peptide.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
N

Clone:
84C4A

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.02% sodium azide

Gene Alias:
COVID19 Nucleocapsid, COVID-19 nucleocapsid, COVID19 Spike nucleocapsid, SARS-CoV-2 N

Gene Symbols:
N

Isotype:
IgG1 κ

Purification Method:
Protein A

Product Type:
Antibody