PIMA537314

Phospho-PTEN (Ser380) Recombinant Rabbit Monoclonal Antibody (PTENS380-NA9), FITC, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA537314-Each-of-1 In Stock ₹ 18,994.32

PIMA537314 - Each of 1

₹ 18,994.32

In Stock

Quantity

1

Base Price: ₹ 18,994.32

GST (18%): ₹ 3,418.978

Total Price: ₹ 22,413.298

Antigen

Phospho-PTEN (Ser380)

Classification

Monoclonal

Conjugate

FITC

Gene

PTEN

Gene Alias

10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

19211, 5728

Content And Storage

4° C, store in dark

Form

Liquid

Applications

Flow Cytometry

Clone

PTENS380-NA9

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.

O08586, P60484

Gene Symbols

PTEN

Immunogen

A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.

Quantity

10 Tests

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG κ

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Description

  • PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency
  • The PTEN gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase
  • It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases
  • Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates
  • PTEN negatively regulates intracellular levels of phosphatidylinositol-3, 4, 5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway
  • PTEN plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation
  • Also, PTEN may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue
  • The nuclear monoubiquitinated form possesses greater apoptotic potential, whereas the cytoplasmic nonubiquitinated form of PTEN induces less tumor suppressive ability.

Compare Similar Items

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Img

Fischer Scientific

PIMA537314

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Antigen:
Phospho-PTEN (Ser380)

Classification:
Monoclonal

Conjugate:
FITC

Gene:
PTEN

Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
19211, 5728

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Flow Cytometry

Clone:
PTENS380-NA9

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
O08586, P60484

Gene Symbols:
PTEN

Immunogen:
A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.

Quantity:
10 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Img

Fischer Scientific

PIMA537315

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Antigen:
Phospho-PTEN (Ser380)

Classification:
Monoclonal

Conjugate:
APC

Gene:
PTEN

Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
19211, 5728

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
PTENS380-NA9

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
O08586, P60484

Gene Symbols:
PTEN

Immunogen:
A synthetic phospho peptide corresponding to residues surrounding Ser380 of human phospho PTEN.

Quantity:
10 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Img

Fischer Scientific

PIMA537320

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Antigen:
Phospho-BAD (Ser112)

Classification:
Monoclonal

Conjugate:
APC

Gene:
BAD

Gene Alias:
AI325008; BAD; Bbc2; Bbc6; Bcl2 antagonist of cell death; BCL2 associated agonist of cell death; bcl-2 associated death agonist; Bcl2-antagonist of cell death; BCL2-antagonist of cell death protein; bcl2-associated agonist of cell death; bcl2-associated death promoter; bcl-2-binding component 6; BCL2-binding component 6; BCL2-binding protein; BCL2L8; bcl2-L-8; Bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; hypothetical protein LOC615013; OTTMUSP00000017561; OTTMUSP00000022400

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
12015, 572, 64639

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
BADS112-B9

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
O35147, Q61337, Q92934

Gene Symbols:
BAD

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser112 of human phospho BAD.

Quantity:
10 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG λ

Img

Fischer Scientific

PIMA537321

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Antigen:
Phospho-Stat5 (Tyr694)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
STAT5A

Gene Alias:
AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
20850, 6776

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry

Clone:
Stat5Y694-B5

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P42229, P42230

Gene Symbols:
STAT5A

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr694 of human phospho Stat5.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ