7215260

Phospho-PKC alpha (Thr497) Recombinant Rabbit Monoclonal Antibody (PKCaT497-F1), PE, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-PKC alpha (Thr497)

Applications

Flow Cytometry

Conjugate

PE

Host Species

Rabbit

Target Species

Human, Mouse, Rat

Gene Accession No.

P05696, P17252, P20444

Gene ID (Entrez)

18750, 24680, 5578

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Thr497 of human phospho PKC alpha.

Primary or Secondary

Primary

Content And Storage

4° C

Gene

PRKCA

Clone

PKCaT497-F1

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias

AAG6; aging-associated gene 6; AI875142; EC 2.7.11.13; FHC; FTH; FTHL6; im:7139045; kinase PKC-alpha; KPCA; MGC104426; PIG15; PKC III; Pkca; PKC-A; PKC-alpha; PKC-III; PKRCA; PLIF; PRKACA; Prkca; prkcaa; protein kinase C; protein kinase C alpha; protein kinase C alpha type; protein kinase C alpha type; protein kinase C, alpha, a; protein kinase C, alpha; protein kinase C, alpha, a; protein kinase c-alpha; si:dkey-8l19.1; Unknown (protein for IMAGE:7139045); unnamed protein product

Gene Symbols

PRKCA

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

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Description

  • Description The PKC family of serine/threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways
  • In humans, at least 12 different PKC polypeptides have been identified
  • These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity
  • PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent
  • Protein kinase C (PKC) can be activated by calcium and the second messenger diacylglycerol
  • PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways
  • PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters
  • Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells
  • The protein encoded by this gene is one of the PKC family members
  • This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control
  • Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

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Img

Fischer Scientific

7215260

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-PKC alpha (Thr497)

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P05696, P17252, P20444

Gene ID (Entrez):
18750, 24680, 5578

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr497 of human phospho PKC alpha.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
PRKCA

Clone:
PKCaT497-F1

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
AAG6; aging-associated gene 6; AI875142; EC 2.7.11.13; FHC; FTH; FTHL6; im:7139045; kinase PKC-alpha; KPCA; MGC104426; PIG15; PKC III; Pkca; PKC-A; PKC-alpha; PKC-III; PKRCA; PLIF; PRKACA; Prkca; prkcaa; protein kinase C; protein kinase C alpha; protein kinase C alpha type; protein kinase C alpha type; protein kinase C, alpha, a; protein kinase C, alpha; protein kinase C, alpha, a; protein kinase c-alpha; si:dkey-8l19.1; Unknown (protein for IMAGE:7139045); unnamed protein product

Gene Symbols:
PRKCA

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215261

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-SLP76 (Tyr128)

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q13094, Q60787

Gene ID (Entrez):
16822, 3937

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr128 of human phospho SLP-76.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
LCP2

Clone:
SLP76Y128-3F8

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm

Gene Symbols:
LCP2

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215261

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-SLP76 (Tyr128)

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q13094, Q60787

Gene ID (Entrez):
16822, 3937

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr128 of human phospho SLP-76.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
LCP2

Clone:
SLP76Y128-3F8

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm

Gene Symbols:
LCP2

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215262

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-SHP-1 (Tyr536)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P29350

Gene ID (Entrez):
5777

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
PTPN6

Clone:
Shp1Y536-2A7

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Gene Symbols:
PTPN6

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody