7215264
Phospho-PTEN (Ser380, Thr382, Thr383) Recombinant Rabbit Monoclonal Antibody (PTENS380T382383-E4), PE, Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Phospho-PTEN (Ser380, Thr382, Thr383)
Applications
Flow Cytometry
Conjugate
PE
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
O08586, P60484
Gene ID (Entrez)
19211, 5728
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.
Primary or Secondary
Primary
Content And Storage
4° C
Gene
PTEN
Clone
PTENS380T382383-E4
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Gene Symbols
PTEN
Isotype
IgG κ
Purification Method
Protein A/G
Product Type
Antibody
Description
- PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency
- The PTEN gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase
- It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases
- Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates
- PTEN negatively regulates intracellular levels of phosphatidylinositol-3, 4, 5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway
- PTEN plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation
- Also, PTEN may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue
- The nuclear monoubiquitinated form possesses greater apoptotic potential, whereas the cytoplasmic nonubiquitinated form of PTEN induces less tumor suppressive ability.
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Antigen: Phospho-PTEN (Ser380, Thr382, Thr383)
Applications: Flow Cytometry
Conjugate: PE
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: O08586, P60484
Gene ID (Entrez): 19211, 5728
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: PTEN
Clone: PTENS380T382383-E4
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: 10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Gene Symbols: PTEN
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Phospho-PTEN (Ser380, Thr382, Thr383)
Applications:
Flow Cytometry
Conjugate:
PE
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
O08586, P60484
Gene ID (Entrez):
19211, 5728
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
PTEN
Clone:
PTENS380T382383-E4
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Gene Symbols:
PTEN
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Antigen: Phospho-PLCg2 (Tyr759)
Applications: Flow Cytometry
Conjugate: PE
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P16885, Q8CIH5
Gene ID (Entrez): 234779, 5336
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr759 of human phospho PLCg2.
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: Plcg2
Clone: PLCG2Y759-G3
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV
Gene Symbols: Plcg2
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Phospho-PLCg2 (Tyr759)
Applications:
Flow Cytometry
Conjugate:
PE
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P16885, Q8CIH5
Gene ID (Entrez):
234779, 5336
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr759 of human phospho PLCg2.
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
Plcg2
Clone:
PLCG2Y759-G3
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV
Gene Symbols:
Plcg2
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Antigen: Phospho-HCLS1 (Tyr397)
Applications: Flow Cytometry
Conjugate: APC
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P14317, P49710
Gene ID (Entrez): 15163, 3059
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr397 of human phospho HS1.
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: HCLS1
Clone: HS1Y397-F12
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: AW213261; CTTNL; HCLS1; hematopoietic cell specific Lyn substrate 1; hematopoietic cell-specific Lyn substrate 1; Hematopoietic lineage cell-specific protein; HS1; LckBP1; p75
Gene Symbols: HCLS1
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen:
Phospho-HCLS1 (Tyr397)
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P14317, P49710
Gene ID (Entrez):
15163, 3059
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr397 of human phospho HS1.
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
HCLS1
Clone:
HS1Y397-F12
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias:
AW213261; CTTNL; HCLS1; hematopoietic cell specific Lyn substrate 1; hematopoietic cell-specific Lyn substrate 1; Hematopoietic lineage cell-specific protein; HS1; LckBP1; p75
Gene Symbols:
HCLS1
Isotype:
IgG κ
Purification Method:
Protein A/G
Product Type:
Antibody
Antigen: SARS-CoV-2 Nucleocapsid
Applications: ELISA
Conjugate: Biotin
Host Species: Rabbit
Target Species: Virus
Gene Accession No.: P0DTC9
Gene ID (Entrez): 43740575
Immunogen: SARS-CoV-2 nucleoprotein (NP) specific peptide.
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: N
Clone: 84C4A
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.02% sodium azide
Gene Alias: COVID19 Nucleocapsid, COVID-19 nucleocapsid, COVID19 Spike nucleocapsid, SARS-CoV-2 N
Gene Symbols: N
Isotype: IgG1 κ
Purification Method: Protein A
Product Type: Antibody
Antigen:
SARS-CoV-2 Nucleocapsid
Applications:
ELISA
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Virus
Gene Accession No.:
P0DTC9
Gene ID (Entrez):
43740575
Immunogen:
SARS-CoV-2 nucleoprotein (NP) specific peptide.
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
N
Clone:
84C4A
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.02% sodium azide
Gene Alias:
COVID19 Nucleocapsid, COVID-19 nucleocapsid, COVID19 Spike nucleocapsid, SARS-CoV-2 N
Gene Symbols:
N
Isotype:
IgG1 κ
Purification Method:
Protein A
Product Type:
Antibody