7218684

CD23 Monoclonal Antibody (EBVCS2), PerCP-Cyanine5.5, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD23

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias

BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; Fce2; fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; lymphocyte IgE receptor

Gene Symbols

FCER2

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

FCER2

Clone

EBVCS2

Applications

Flow Cytometry

Conjugate

PerCP-Cyanine5.5

Host Species

Mouse

Target Species

Human

Gene Accession No.

P06734

Gene ID (Entrez)

2208

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • Description: The EBVCS2 monoclonal antibody reacts with human CD23, a 45 kDa type II transmembrane glycoprotein
  • CD23 is expressed on mature B cells, mantle zone B cells, follicular dendritic cells and at low levels on T, NK, langerhans cells and platelets
  • Expression of CD23 is upregulated upon B cell activation, and soluble forms of the antigen have been reported to be biologically active
  • CD23 is a low affinity receptor for IgE and is thought to play a role in the regulation of IgE response and B cell activation
  • CD21 and the alpha subunit of CD11b and CD11c bind to CD23
  • Applications Reported: This EBVCS2 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This EBVCS2 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at 5 μL (0.25 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 488 nm; Emission: 695 nm; Laser: Blue Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts
  • The CD23 molecule is identical to the low affinity IgE receptor found on B cells
  • Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma
  • CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts
  • Functionally, CD23 is involved in B cell growth and differentiation, and IgE production
  • Further, CD23 has a soluble form that is a potent mitogenic factor
  • Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.

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Antigen:
CD23

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; Fce2; fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; lymphocyte IgE receptor

Gene Symbols:
FCER2

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
FCER2

Clone:
EBVCS2

Applications:
Flow Cytometry

Conjugate:
PerCP-Cyanine5.5

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P06734

Gene ID (Entrez):
2208

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
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Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
CD44; CD44 antigen; CD44 molecule (Indian blood group); CD44A; Cell surface glycoprotein CD44 (hyaluronate binding protein); ECMR-III; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; Hermes antigen; HUTCH-I; Hyaluronate receptor; METAA; PGP-1; PGP-I; Phagocytic glycoprotein 1; phagocytic glycoprotein I; RHAMM

Gene Symbols:
Cd44

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Cd44

Clone:
OX49

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Mouse

Target Species:
Rat

Gene Accession No.:
P26051

Gene ID (Entrez):
25406

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Mouse Isotype Control...


Antigen:
Mouse IgG1 kappa

Concentration:
1 mg/mL

Classification:
__

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative; pH 7.2

Gene Alias:
IgG1; Igh-4; Ighg1; Immunoglobulin G; Immunoglobulin G1; immunoglobulin heavy constant gamma 1 (G1m marker); ImmunoglobulinG; ImmunoglobulinG1; VH7183

Gene Symbols:
__

Primary or Secondary:
Isotype Control (Primary)

Content And Storage:
4° C

Gene:
__

Clone:
P3.6.2.8.1

Applications:
Control, Flow Cytometry, Functional Assay

Conjugate:
Functional Grade

Host Species:
Mouse

Target Species:
Not Applicable

Gene Accession No.:
__

Gene ID (Entrez):
__

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
__

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Antigen:
Globo H

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with proprietary stabilizer and 0.09% sodium azide; pH 7.2

Gene Alias:
Globo H antigen; globoH; Globohexaosylceramide

Gene Symbols:
__

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
__

Clone:
VK9

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
__

Gene ID (Entrez):
__

Isotype:
IgG3 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody