7222835
CD23 Monoclonal Antibody (B3B4), Brilliant Ultra Violet™ 805, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD23
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Gene Accession No.
P20693
Gene ID (Entrez)
14128
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Gene
Fcer2a
Clone
B3B4
Applications
Flow Cytometry
Conjugate
Brilliant Ultraviolet 805
Host Species
Rat
Target Species
Mouse
Gene Alias
BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; Fce2; fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; lymphocyte IgE receptor
Gene Symbols
Fcer2a
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- The B3B4 monoclonal antibody reacts with mouse CD23, a 45 kDa type II transmembrane glycoprotein
- CD23 is expressed on resting conventional B cells, and its expression is modulated upon B-cell activation
- B-1 cell lineage (CD5+ B cells) does not express CD23
- Soluble forms of the antigen have been reported to be biologically active
- CD23 is a low affinity receptor for IgE and is thought to play a role in the regulation of IgE response and B-cell activation
- CD21 is thought to bind to CD23
- Applications Reported: This B3B4 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This B3B4 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This may be used at less than or equal to 1.0 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Brilliant Ultraviolet 805 is a tandem dye that emits at 797 nm and is intended for use on cytometers equipped with an ultraviolet (355 nm) laser
- CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts
- The CD23 molecule is identical to the low affinity IgE receptor found on B cells
- Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma
- CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts
- Functionally, CD23 is involved in B cell growth and differentiation, and IgE production
- Further, CD23 has a soluble form that is a potent mitogenic factor
- Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
Compare Similar Items
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Antigen: CD23
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Gene Accession No.: P20693
Gene ID (Entrez): 14128
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: Fcer2a
Clone: B3B4
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 805
Host Species: Rat
Target Species: Mouse
Gene Alias: BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; Fce2; fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; lymphocyte IgE receptor
Gene Symbols: Fcer2a
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
CD23
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Gene Accession No.:
P20693
Gene ID (Entrez):
14128
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
Fcer2a
Clone:
B3B4
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 805
Host Species:
Rat
Target Species:
Mouse
Gene Alias:
BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; Fce2; fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; lymphocyte IgE receptor
Gene Symbols:
Fcer2a
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: CD25
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Gene Accession No.: P01590
Gene ID (Entrez): 16184
Isotype: IgG1 λ
Purification Method: Affinity chromatography
Gene: IL2RA
Clone: PC61.5
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 805
Host Species: Rat
Target Species: Mouse
Gene Alias: ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR
Gene Symbols: IL2RA
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
CD25
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Gene Accession No.:
P01590
Gene ID (Entrez):
16184
Isotype:
IgG1 λ
Purification Method:
Affinity chromatography
Gene:
IL2RA
Clone:
PC61.5
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 805
Host Species:
Rat
Target Species:
Mouse
Gene Alias:
ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR
Gene Symbols:
IL2RA
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: CD27
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Gene Accession No.: P26842
Gene ID (Entrez): 939
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Gene: CD27
Clone: O323
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 805
Host Species: Mouse
Target Species: Human
Gene Alias: CD antigen 27; CD27; CD27 antigen; CD27 molecule; CD27L receptor; LPFS2; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7
Gene Symbols: CD27
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
CD27
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Gene Accession No.:
P26842
Gene ID (Entrez):
939
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Gene:
CD27
Clone:
O323
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 805
Host Species:
Mouse
Target Species:
Human
Gene Alias:
CD antigen 27; CD27; CD27 antigen; CD27 molecule; CD27L receptor; LPFS2; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7
Gene Symbols:
CD27
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: CD39
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Gene Accession No.: P55772
Gene ID (Entrez): 12495
Isotype: IgG2b κ
Purification Method: Affinity chromatography
Gene: ENTPD1
Clone: 24DMS1
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 805
Host Species: Rat
Target Species: Mouse
Gene Alias: 2610206B08Rik; AA408691; ATPDase; Cd39; CD39 antigen; DKFZp686D194; DKFZp686I093; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase-1; SPG64
Gene Symbols: ENTPD1
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
CD39
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Gene Accession No.:
P55772
Gene ID (Entrez):
12495
Isotype:
IgG2b κ
Purification Method:
Affinity chromatography
Gene:
ENTPD1
Clone:
24DMS1
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 805
Host Species:
Rat
Target Species:
Mouse
Gene Alias:
2610206B08Rik; AA408691; ATPDase; Cd39; CD39 antigen; DKFZp686D194; DKFZp686I093; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase-1; SPG64
Gene Symbols:
ENTPD1
Primary or Secondary:
Primary
Product Type:
Antibody