7222840

CD39 Monoclonal Antibody (24DMS1), Brilliant Ultra Violet™ 805, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD39

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias

2610206B08Rik; AA408691; ATPDase; Cd39; CD39 antigen; DKFZp686D194; DKFZp686I093; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase-1; SPG64

Gene Symbols

ENTPD1

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

ENTPD1

Clone

24DMS1

Applications

Flow Cytometry

Conjugate

Brilliant Ultraviolet 805

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P55772

Gene ID (Entrez)

12495

Isotype

IgG2b κ

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • The 24DMS1 monoclonal antibody reacts with mouse CD39, also known as NTPDaseI
  • E-NTPDases are enzymes that convert nucleoside tri- and diphosphates (NTDPs) into nucleoside monophosphate (NMP), thereby removing toxic extracellular ATP and ADP
  • CD39 is the dominant member of this family in the immune system and is involved in suppression of inflammation and control of platelet activation
  • CD39 can impact expression of CD73, another E-NTPase
  • Together, these molecules influence inflammation responses
  • CD39 is expressed on B cells, Langerhans cells and most monocytes
  • In addition, CD39 is found on a subset of CD4+ T cells that are mostly CD25+FoxP3+ T reg cells
  • T reg cells from CD39-null mice showed impaired suppressive properties in vitro and in vivo
  • Applications Reported: This 24DMS1 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 24DMS1 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This may be used at less than or equal to 1.0 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Brilliant Ultraviolet 805 is a tandem dye that emits at 797 nm and is intended for use on cytometers equipped with an ultraviolet (355 nm) laser
  • CD39 cell surface antigen is a 70-100kD molecule expressed on peripheral blood B cells, monocytes, T cell clones, and also weakly expressed on granulocytes
  • CD39 has intrinsic ecto-ATPase activity
  • Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen.

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Antigen:
CD39

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
2610206B08Rik; AA408691; ATPDase; Cd39; CD39 antigen; DKFZp686D194; DKFZp686I093; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase-1; SPG64

Gene Symbols:
ENTPD1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
ENTPD1

Clone:
24DMS1

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 805

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P55772

Gene ID (Entrez):
12495

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD39

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
2610206B08Rik; AA408691; ATPDase; Cd39; CD39 antigen; DKFZp686D194; DKFZp686I093; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase-1; SPG64

Gene Symbols:
ENTPD1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
ENTPD1

Clone:
eBioA1 (A1)

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 805

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P49961

Gene ID (Entrez):
953

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD45

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Gene Symbols:
PTPRC

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
PTPRC

Clone:
30-F11

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 805

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P06800

Gene ID (Entrez):
19264

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD45R (B220)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen

Gene Symbols:
PTPRC

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
PTPRC

Clone:
RA3-6B2

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 805

Host Species:
Rat

Target Species:
Human, Mouse

Gene Accession No.:
P06800, P08575

Gene ID (Entrez):
19264, 5788

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody