7222855
CD223 (LAG-3) Monoclonal Antibody (3DS223H), Brilliant Ultra Violet™ 805, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD223 (LAG-3)
Concentration
5 μL/Test
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Gene Accession No.
P18627
Gene ID (Entrez)
3902
Immunogen
hCD223-FC PFA 4%
Primary or Secondary
Primary
Product Type
Antibody
Clone
3DS223H
Applications
Flow Cytometry
Conjugate
Brilliant Ultraviolet 805
Host Species
Mouse
Target Species
Human
Gene Alias
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3
Gene Symbols
LAG3
Isotype
IgG1 κ
Purification Method
Affinity chromatography
Gene
LAG3
Related Products
Description
- The 3DS223H monoclonal antibody recognizes human CD223 also known as Lymphocyte Activation Gene 3 (LAG-3)
- LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4
- LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation
- Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells
- CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells
- Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells)
- This 3DS223H antibody will recognize a formaldehyde-fixed epitope
- Applications Reported: This 3DS223H antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 3DS223H antibody has been pre-diluted and tested by flow cytometric analysis of stimulated normal human peripheral blood cells
- This may be used at 5 μL (0.5 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Brilliant Ultraviolet 805 is a tandem dye that emits at 797 nm and is intended for use on cytometers equipped with an ultraviolet (355 nm) laser
- LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4
- LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation
- Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells
- CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells
- Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).
Compare Similar Items
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Antigen: CD223 (LAG-3)
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Gene Accession No.: P18627
Gene ID (Entrez): 3902
Immunogen: hCD223-FC PFA 4%
Primary or Secondary: Primary
Product Type: Antibody
Clone: 3DS223H
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 805
Host Species: Mouse
Target Species: Human
Gene Alias: Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3
Gene Symbols: LAG3
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Gene: LAG3
Antigen:
CD223 (LAG-3)
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Gene Accession No.:
P18627
Gene ID (Entrez):
3902
Immunogen:
hCD223-FC PFA 4%
Primary or Secondary:
Primary
Product Type:
Antibody
Clone:
3DS223H
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 805
Host Species:
Mouse
Target Species:
Human
Gene Alias:
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3
Gene Symbols:
LAG3
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Gene:
LAG3
Antigen: CD366 (TIM3)
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Gene Accession No.: Q8TDQ0
Gene ID (Entrez): 84868
Immunogen: __
Primary or Secondary: Primary
Product Type: Antibody
Clone: F38-2E2
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 805
Host Species: Mouse
Target Species: Human
Gene Alias: CD366; FLJ14428; Havcr2; HAVcr-2; Hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; kidney injury molecule-3; KIM-3; sCD366; soluble CD366; soluble TIM 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; Tim3; TIM-3; TIMD3; TIMD-3
Gene Symbols: Havcr2
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Gene: Havcr2
Antigen:
CD366 (TIM3)
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Gene Accession No.:
Q8TDQ0
Gene ID (Entrez):
84868
Immunogen:
__
Primary or Secondary:
Primary
Product Type:
Antibody
Clone:
F38-2E2
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 805
Host Species:
Mouse
Target Species:
Human
Gene Alias:
CD366; FLJ14428; Havcr2; HAVcr-2; Hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; kidney injury molecule-3; KIM-3; sCD366; soluble CD366; soluble TIM 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; Tim3; TIM-3; TIMD3; TIMD-3
Gene Symbols:
Havcr2
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Gene:
Havcr2
Antigen: Arginase 1
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Gene Accession No.: P05089, Q61176
Gene ID (Entrez): 11846, 383
Immunogen: E.coli-derived recombinant mouse Arginase 1
Primary or Secondary: Primary
Product Type: Antibody
Clone: A1exF5
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 805
Host Species: Rat
Target Species: Human, Mouse
Gene Alias: AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase
Gene Symbols: ARG1
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: ARG1
Antigen:
Arginase 1
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Gene Accession No.:
P05089, Q61176
Gene ID (Entrez):
11846, 383
Immunogen:
E.coli-derived recombinant mouse Arginase 1
Primary or Secondary:
Primary
Product Type:
Antibody
Clone:
A1exF5
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 805
Host Species:
Rat
Target Species:
Human, Mouse
Gene Alias:
AI; A-I; AI type I arginase; AI256583; Arg1; Arg-1; Arginase; arginase 1; arginase 1 liver; arginase 1, liver; arginase I; arginase, liver; Arginase1; arginase-1; HGNC:663; Liver Arginase; Liver-type arginase; PGIF; similar to arginase, type I; Type 1 Arginase; type I arginase
Gene Symbols:
ARG1
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
ARG1
Antigen: Ki-67
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Gene Accession No.: E9PVX6, P46013
Gene ID (Entrez): 100686578, 102135895, 17345, 291234, 4288
Immunogen: __
Primary or Secondary: Primary
Product Type: Antibody
Clone: SolA15
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 805
Host Species: Rat
Target Species: Canine, Cynomolgus Monkey, Human, Mouse, Non-human Primate, Rat
Gene Alias: antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05
Gene Symbols: Mki67
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: Mki67
Antigen:
Ki-67
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Gene Accession No.:
E9PVX6, P46013
Gene ID (Entrez):
100686578, 102135895, 17345, 291234, 4288
Immunogen:
__
Primary or Secondary:
Primary
Product Type:
Antibody
Clone:
SolA15
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 805
Host Species:
Rat
Target Species:
Canine, Cynomolgus Monkey, Human, Mouse, Non-human Primate, Rat
Gene Alias:
antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05
Gene Symbols:
Mki67
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
Mki67