BD Horizon™ HLA-DR Mouse, anti-Human, RY586, Clone: G46-6, BD Horizon™

Description

• Description The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen
• HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6
• HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells
• HLA-DR is also expressed on activated T cells
• This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.