7240390

ST2 Monoclonal Antibody (12), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

ST2

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2

Gene Symbols

IL1RL1

Isotype

IgG2b

Purification Method

Protein A

Product Type

Antibody

Clone

12

Applications

ELISA

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

Q01638

Gene ID (Entrez)

9173

Immunogen

Recombinant human IL1RL1/IL1R4 protein

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Gene

IL1RL1

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Description

  • Specificity: Human IL1RL1/IL1R4 IL-33R, also known as ST2, is a receptor for IL-33
  • It is a member of the IL-1 receptor family of innate receptors
  • Its extracellular domain consists of 3 Ig-like domains that directly interact with its co-receptor IL-1RAcP, and the ligand alarmin, IL-33
  • IL-33 ligation results in the association of IL-33R complex with its adaptor proteins MyD88, IRAK1, IRAK4 and TRAF6, and activation of the NF-kB, and MAPK pathways
  • This, in turn, instigates the release of chemokines and cytokines such as IL-5, IL-6, IL-8, and IL-13
  • Two most common isoforms of IL-33R that result from alternative splicing are ST2L – the membrane bound form, and ST2S – the soluble form
  • The membrane bound form can be released from the cell surface by proteolytic cleavage
  • The soluble forms have been suggested to act as decoys dampening the IL-33 signaling
  • IL-33R is primarily expressed by mast cells, basophils, and eosinophils
  • In mouse, IL-33R expression has been shown on ILC2 and Th2 cells
  • IL-33R signaling has been implicated in the number of immune conditions, including allergies, arthritis, atherosclerosis and sepsis.

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Fischer Scientific

7240390

Mouse Monoclonal Antibody...


Antigen:
ST2

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2

Gene Symbols:
IL1RL1

Isotype:
IgG2b

Purification Method:
Protein A

Product Type:
Antibody

Clone:
12

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q01638

Gene ID (Entrez):
9173

Immunogen:
Recombinant human IL1RL1/IL1R4 protein

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
IL1RL1

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Mouse Monoclonal Antibody...


Antigen:
Ephrin A1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AI325262; B61; ECKLG; EFL1; Efna1; Epgl1; EPH-related receptor tyrosine kinase ligand 1; ephrin A1; ephrin-A1; Ephrin-A1, secreted form; Epl1; EPLG1; Immediate early response protein B61; Lerk1; LERK-1; ligand of eph-related kinase 1; TNF alpha-induced protein 4; TNFAIP4; tumor necrosis factor alpha-induced protein 4; tumor necrosis factor, alpha-induced protein 4

Gene Symbols:
EFNA1

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

Clone:
3F7H7F6

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P20827

Gene ID (Entrez):
1942

Immunogen:
Recombinant Human EFNA1 protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
EFNA1

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7240396

Rabbit Recombinant Monoclonal Antib...


Antigen:
E-selectin

Concentration:
1 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
CD62 antigen-like family member E; CD62E; e selectin; Elam; ELAM1; ELAM-1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule; endothelial leukocyte adhesion molecule 1; endothelial leukocyte adhesion molecule I; ESEL; E-selectin; LECAM2; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; RP1-117P20.2; SELE; selectin E; selectin E (endothelial adhesion molecule 1); selectin, endothelial cell

Gene Symbols:
SELE

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

Clone:
40

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P16581

Gene ID (Entrez):
6401

Immunogen:
Recombinant Human CD62E protein.

Primary or Secondary:
Primary

Content And Storage:
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Gene:
SELE

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Antigen:
TrkC

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AW125844; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; neural receptor protein-tyrosine kinase (trkC); neurotrophic receptor tyrosine kinase 3; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; neurotrophin-3; NT-3 growth factor receptor; NTRK3; Ntrk3_tv3; TrkC; trk-C; trkC tyrosine kinase; tyrosine kinase receptor; tyrosine kinase receptor C

Gene Symbols:
Ntrk3

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

Clone:
11

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q16288

Gene ID (Entrez):
4916

Immunogen:
Recombinant Human TrkC/NTRK3 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
Ntrk3