7240525

CD86 (B7-2) Monoclonal Antibody (10), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD86 (B7-2)

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Gene Symbols

CD86

Isotype

IgG2b

Purification Method

Protein A

Product Type

Antibody

Clone

10

Applications

Flow Cytometry

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Rat

Gene Accession No.

0

Gene ID (Entrez)

56822

Immunogen

Recombinant Rat CD86/B7-2 Protein.

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Gene

CD86

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Description

  • Specificity: Rat CD86/B7-2 CD86 is one of two ligands (the other CD80) for CTLA4 and CD28
  • CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation
  • Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance
  • CD80 appears to play a role distinct from CD80 in T helper cell differentiation
  • CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily
  • The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4
  • Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell
  • Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response
  • Alternative splicing results in two transcript variants encoding different isoforms of CD86
  • Additional transcript variants have been described for CD86, but their full-length sequences have not been determined
  • Diseases associated with CD86 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

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Show Difference

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Fischer Scientific

7240525

Mouse Monoclonal Antibody...


Antigen:
CD86 (B7-2)

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Gene Symbols:
CD86

Isotype:
IgG2b

Purification Method:
Protein A

Product Type:
Antibody

Clone:
10

Applications:
Flow Cytometry

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Rat

Gene Accession No.:
0

Gene ID (Entrez):
56822

Immunogen:
Recombinant Rat CD86/B7-2 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
CD86

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7240528

Mouse Monoclonal Antibody...


Antigen:
IL1F5

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AI413231; FIL1; FIL1 delta; FIL1(DELTA); FIL1D; Fil1delta; IL-1 delta; IL-1 related protein 3; Il1f5; IL-1F5; IL1F5 (Canonical product IL-1F5a); IL-1F5 (IL-1HY1, FIL1-delta, IL-1RP3, IL-1L1, IL-1-delta); Il1h3; Il-1h3; IL1HY1; IL-1HY1; IL1L1; IL-1L1; IL-1ra homolog 1; IL-1-related protein 3; IL1RP3; IL-1RP3; IL36RA; IL-36Ra; IL36RN; interleukin 1 family, member 5; interleukin 1 family, member 5 (delta); interleukin 1 receptor antagonist homolog 1; interleukin 36 receptor antagonist; interleukin-1 delta; Interleukin-1 family member 5; interleukin-1 family member 5; interleukin-36 receptor antagonist protein; interleukin-1 homolog 3; Interleukin-1 HY1; interleukin-1 receptor antagonist homolog 1; Interleukin-1-like protein 1; interleukin-36 receptor antagonist protein; MGC29840; PSORP; PSORS14; UNQ1896/PRO4342

Gene Symbols:
IL36RN

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

Clone:
04

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q9UBH0

Gene ID (Entrez):
26525

Immunogen:
Recombinant Human IL-1F5 Protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
IL36RN

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7240532

Rabbit Recombinant Monoclonal Antib...


Antigen:
Carbonic Anhydrase XIII

Concentration:
1 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
2310075C21Rik; Ca13; Car13; Carbonate dehydratase XIII; carbonic anhydrase 13; Carbonic anhydrase XIII; CAXIII; CA-XIII; RGD1560453

Gene Symbols:
Ca13

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

Clone:
103

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q8N1Q1

Gene ID (Entrez):
377677

Immunogen:
Recombinant Human Carbonic Anhydrase XIII/CA13 protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
Ca13

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7240532

Rabbit Recombinant Monoclonal Antib...


Antigen:
Carbonic Anhydrase XIII

Concentration:
1 mg/mL

Classification:
Recombinant Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
2310075C21Rik; Ca13; Car13; Carbonate dehydratase XIII; carbonic anhydrase 13; Carbonic anhydrase XIII; CAXIII; CA-XIII; RGD1560453

Gene Symbols:
Ca13

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

Clone:
103

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q8N1Q1

Gene ID (Entrez):
377677

Immunogen:
Recombinant Human Carbonic Anhydrase XIII/CA13 protein.

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Gene:
Ca13