7240806

Klotho Monoclonal Antibody (C3), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Klotho

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

alpha-kl; HFTC3; Kl; Klotho; Klotho peptide; secreted form of Klotho protein

Gene Symbols

KL

Isotype

IgG1 κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

C3

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Rat

Gene Accession No.

Q9UEF7, Q9Z2Y9

Gene ID (Entrez)

83504, 9365

Immunogen

Phe765-Ser981 (Accession Q9UEF7), with Two N-terminal Tags, His-tag and SUMO-tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

KL

Related Products

Img

Fischer Scientific

PIMA543727

--

Img

Fischer Scientific

PIMA543726

--

Img

Fischer Scientific

7226347

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7240803

Mouse Monoclonal Antibody...

Img

Fischer Scientific

PIPA5122018

--

Img

Fischer Scientific

PIPA5122019

--

Img

Fischer Scientific

7240877

Mouse Monoclonal Antibody...

Img

Fischer Scientific

PIMA543731

--

Description

  • KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily
  • It encodes a type I membrane protein that is abundant in the kidney and brain
  • In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility
  • Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling
  • KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7240806

Mouse Monoclonal Antibody...


Antigen:
Klotho

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
alpha-kl; HFTC3; Kl; Klotho; Klotho peptide; secreted form of Klotho protein

Gene Symbols:
KL

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C3

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Rat

Gene Accession No.:
Q9UEF7, Q9Z2Y9

Gene ID (Entrez):
83504, 9365

Immunogen:
Phe765-Ser981 (Accession Q9UEF7), with Two N-terminal Tags, His-tag and SUMO-tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
KL

Img

Fischer Scientific

7240809

Rabbit Polyclonal Antibody...


Antigen:
PXDN

Concentration:
0.5 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
2310075M15Rik; C85409; COPOA; D2S448; D2S448E; E330004E07; Kiaa0230; Melanoma-associated antigen MG50; MG50; mKIAA0230; p53-responsive gene 2 protein; PE responsive protein c64; Perc64; peroxidasin; peroxidasin homolog; peroxidasin homolog (Drosophila); PRG2; PXDN; PXN; Vascular peroxidase 1; VPO; VPO1

Gene Symbols:
PXDN

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Clone:
__

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q92626

Gene ID (Entrez):
7837

Immunogen:
Glu76-Gly260 (Accession Q92626), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
PXDN

Img

Fischer Scientific

7240810

Mouse Monoclonal Antibody...


Antigen:
CD138 (Syndecan-1)

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
AA408134; AA409076; CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; HSPG; sCD138; SDC; Sdc1; soluble CD138; Sstn; syn-1; Synd; SYND1; Synd-1; SYNDECA; syndecan; syndecan 1; syndecan proteoglycan 1; Syndecan1; syndecan-1; synstatin

Gene Symbols:
Sdc1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C3

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P18827

Gene ID (Entrez):
6382

Immunogen:
Gln23-Leu253 (Accession P18827), with N-terminal His and GST Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
Sdc1

Img

Fischer Scientific

7240812

Mouse Monoclonal Antibody...


Antigen:
RNASE3

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
cytotoxic ribonuclease; Ear11; EAR-11; Ear3; ECP; Eosinophil cationic protein; eosinophil cationic protein-like; eosinophil cationic-type ribonuclease 3; Eosinophil secondary granule ribonuclease 11; eosinophil-associated ribonuclease 3; eosinophil-associated, ribonuclease A family, member 3; LOC100361866; mR3; MR-3; murine ribonuclease 3; RAF1; Ribonuclease 3; ribonuclease A family member 3; ribonuclease, RNase A family 3; ribonuclease, RNase A family, 3; RNase 3; RNASE3; RNS3

Gene Symbols:
RNASE3

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C5

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P12724

Gene ID (Entrez):
6037

Immunogen:
Pro30-Val154 (Accession P12724), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
RNASE3