7240863

PTGDS Monoclonal Antibody (C2), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

PTGDS

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

21kDa; Beta-trace protein; cerebrin-28; Glutathione-independent PGD synthase; glutathione-independent PGD synthetase; lipocalin-type prostaglandin D synthase; lipocalin-type prostaglandin-D synthase; LPGDS; L-PGDS; PDS; PGD2; PGD2 synthase; PGDS; PGDS2; PH2DISO; Prostaglandin D synthase; prostaglandin D2 synthase; prostaglandin D2 synthase (21 kDa, brain); prostaglandin D2 synthase (brain); prostaglandin D2 synthase 21kDa (brain); prostaglandin-D2 synthase; Prostaglandin-H2 D-isomerase; Ptgds; Ptgs3; testis tissue sperm-binding protein Li 63n

Gene Symbols

PTGDS

Isotype

IgG2b κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

C2

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P41222

Gene ID (Entrez)

5730

Immunogen

Pro32-Gln190 (Accession P41222), with N-terminal His Tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

PTGDS

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Description

  • The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2)
  • PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system
  • PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation
  • PTGDS has also been implicated in the development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier
  • Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement (NREM) sleep
  • It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system
  • PTGDS is the most abundant protein in the cerebral spinal fluid and recent evidence suggests that PTGDS acts as a Beta-Amyloid chaperone and may have a role in the deposition of Ab plaques in Alzheimer's disease.

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Fischer Scientific

7240863

Mouse Monoclonal Antibody...


Antigen:
PTGDS

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
21kDa; Beta-trace protein; cerebrin-28; Glutathione-independent PGD synthase; glutathione-independent PGD synthetase; lipocalin-type prostaglandin D synthase; lipocalin-type prostaglandin-D synthase; LPGDS; L-PGDS; PDS; PGD2; PGD2 synthase; PGDS; PGDS2; PH2DISO; Prostaglandin D synthase; prostaglandin D2 synthase; prostaglandin D2 synthase (21 kDa, brain); prostaglandin D2 synthase (brain); prostaglandin D2 synthase 21kDa (brain); prostaglandin-D2 synthase; Prostaglandin-H2 D-isomerase; Ptgds; Ptgs3; testis tissue sperm-binding protein Li 63n

Gene Symbols:
PTGDS

Isotype:
IgG2b κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C2

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P41222

Gene ID (Entrez):
5730

Immunogen:
Pro32-Gln190 (Accession P41222), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
PTGDS

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Antigen:
Amylin

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
Amylin; amylin peptide; DAP; Diabetes-associated peptide; IAP; Iapp; Insulinoma amyloid peptide; islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin); Rabbit Anti-Amylin

Gene Symbols:
IAPP

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C2

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P10997

Gene ID (Entrez):
3375

Immunogen:
Synthetic peptide, which is conjugated to OVA. Lys34-Val50 (Accession P10997), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
IAPP

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7240864

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Antigen:
Amylin

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
Amylin; amylin peptide; DAP; Diabetes-associated peptide; IAP; Iapp; Insulinoma amyloid peptide; islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin); Rabbit Anti-Amylin

Gene Symbols:
IAPP

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C2

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P10997

Gene ID (Entrez):
3375

Immunogen:
Synthetic peptide, which is conjugated to OVA. Lys34-Val50 (Accession P10997), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
IAPP

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Antigen:
Endocan

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
0610042H23Rik; AV004503; endocan; endothelial cell specific molecule 1; endothelial cell-specific molecule 1; ESM1; ESM-1; ESM-1 secretory protein; IGFBP-rp6; PG25; pineal specific PG25 protein

Gene Symbols:
ESM1

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C7

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q9NQ30

Gene ID (Entrez):
11082

Immunogen:
Trp20-Arg184 (Accession Q9NQ30), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
ESM1