7240954

SCNN1G Monoclonal Antibody (C1), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

SCNN1G

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

[g]ENaC; amiloride sensitive sodium channel gamma1 subunit; amiloride-sensitive epithelial sodium channel gamma subunit; amiloride-sensitive sodium channel gamma-subunit; amiloride-sensitive sodium channel subunit gamma; BESC3; ENaC; ENaC gamma; ENaC gamma subunit; ENaCG; ENaCgamma; epithelial Na(+) channel subunit gamma; epithelial sodium channel gamma subunit; Gamma ENaC; Gamma NaCH; gamma-ENaC; Gamma-NaCH; nonvoltage-gated sodium channel 1 subunit gamma; PHA 1; PHA1; SCNEG; SCNN 1G; Scnn1g; sodium channe epithelial 1 gamma subunit; sodium channel epithelial 1 gamma subunit; Sodium channel nonvoltage-gated 1 gamma (epithelial); sodium channel, non voltage gated 1 gamma subunit; sodium channel, nonvoltage-gated 1 gamma; sodium channel, nonvoltage-gated 1, gamma; Sodium channel, nonvoltage-gated 1, gamma (epithelial); sodium channel, non-voltage-gated 1, gamma subunit; sodium channel, nonvoltage-gated, type I, gamma

Gene Symbols

SCNN1G

Isotype

IgG1 κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

C1

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P51170

Gene ID (Entrez)

6340

Immunogen

Thr80-Thr401 (Accession P51170), with N-terminal His Tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

SCNN1G

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Description

  • Epithelial sodium channels are amiloride-sensitive members of the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels
  • Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region
  • There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein
  • ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance
  • ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure
  • ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel
  • Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddel's syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).

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Show Difference

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Fischer Scientific

7240954

Mouse Monoclonal Antibody...


Antigen:
SCNN1G

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
[g]ENaC; amiloride sensitive sodium channel gamma1 subunit; amiloride-sensitive epithelial sodium channel gamma subunit; amiloride-sensitive sodium channel gamma-subunit; amiloride-sensitive sodium channel subunit gamma; BESC3; ENaC; ENaC gamma; ENaC gamma subunit; ENaCG; ENaCgamma; epithelial Na(+) channel subunit gamma; epithelial sodium channel gamma subunit; Gamma ENaC; Gamma NaCH; gamma-ENaC; Gamma-NaCH; nonvoltage-gated sodium channel 1 subunit gamma; PHA 1; PHA1; SCNEG; SCNN 1G; Scnn1g; sodium channe epithelial 1 gamma subunit; sodium channel epithelial 1 gamma subunit; Sodium channel nonvoltage-gated 1 gamma (epithelial); sodium channel, non voltage gated 1 gamma subunit; sodium channel, nonvoltage-gated 1 gamma; sodium channel, nonvoltage-gated 1, gamma; Sodium channel, nonvoltage-gated 1, gamma (epithelial); sodium channel, non-voltage-gated 1, gamma subunit; sodium channel, nonvoltage-gated, type I, gamma

Gene Symbols:
SCNN1G

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C1

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P51170

Gene ID (Entrez):
6340

Immunogen:
Thr80-Thr401 (Accession P51170), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
SCNN1G

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7240958

Mouse Monoclonal Antibody...


Antigen:
MMP7

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
HGNC:7174; MAT; Matrilysin; matrilysin, uterine; matrin; matrix metallo protease; matrix metallopeptidase 7; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); matrix metalloproteinase 7 (matrilysin, uterine); matrix metalloproteinase-7; MMP; MMP 7; MMP7; Mmp-7; MMP-7 protein; MMPs; MPMM; MPSL1; PUMP 1; Pump 1 protease; PUMP1; PUMP-1; pump-1 protease; uterine matrilysin; uterine metalloproteinase

Gene Symbols:
MMP7

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
J8

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P09237

Gene ID (Entrez):
4316

Immunogen:
Leu18-Lys267 (Accession P09237), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
MMP7

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7240958

Mouse Monoclonal Antibody...


Antigen:
MMP7

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
HGNC:7174; MAT; Matrilysin; matrilysin, uterine; matrin; matrix metallo protease; matrix metallopeptidase 7; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); matrix metalloproteinase 7 (matrilysin, uterine); matrix metalloproteinase-7; MMP; MMP 7; MMP7; Mmp-7; MMP-7 protein; MMPs; MPMM; MPSL1; PUMP 1; Pump 1 protease; PUMP1; PUMP-1; pump-1 protease; uterine matrilysin; uterine metalloproteinase

Gene Symbols:
MMP7

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
J8

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P09237

Gene ID (Entrez):
4316

Immunogen:
Leu18-Lys267 (Accession P09237), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
MMP7

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Antigen:
GPR35

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
G protein-coupled receptor 35; Gpr35; G-protein coupled receptor 35; KPG_007; KYNA receptor; kynurenic acid receptor

Gene Symbols:
GPR35

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C3

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q9HC97

Gene ID (Entrez):
2859

Immunogen:
Arg240-Ala309 (Accession Q9HC97), with N-terminal His and GST Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
GPR35