7240989

NGF Monoclonal Antibody (C1), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

NGF

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias

B nerve growth factor; beta ngf; beta-nerve growth factor; BetaNGF; beta-NGF; bNGF; b-NGF; HSAN5; MGC161426; MGC161428; nerve growth factor; nerve growth factor (beta polypeptide); nerve growth factor, beta; nerve growth factor, beta polypeptide; nerve growth factor, beta subunit; NGF; NGF b; NGF β; Ngfb; NGFbeta; NGFβ; β nerve growth factor; β NGF; βNGF

Gene Symbols

NGF

Isotype

IgG1 κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

C1

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P01138

Gene ID (Entrez)

4803

Immunogen

Glu19-Arg239 (Accession P01138), with N-terminal His Tag

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

NGF

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Description

  • Nerve growth factor (NGF) influences the survival and differentiation of a variety of neuronal and nonneuronal cells
  • The actions of this polypeptide result from binding to specific cell surface receptors which are present as both high and low affinity sites
  • Although both types of receptor bind NGF only the high affinity form is capable of signal transduction
  • Cross-linking studies with 125I-NGF have shown that the high affinity receptor of rat PC12 cells forms an Mr 158,000 complex with NGF while the low affinity receptor forms an Mr 100,000 complex
  • Full length cDNA clones for both the human and rat NGF receptor genes have been produced and sequenced, revealing greater than 90% homology between the two species
  • NGF exhibits nerve growth stimulating activity and is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons
  • Further, NGF stimulates division and differentiation of sympathetic and embryonic sensory neurons
  • Mutations in the NGF gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of NGF gene expression is associated with allergic rhinitis.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7240989

Mouse Monoclonal Antibody...


Antigen:
NGF

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
B nerve growth factor; beta ngf; beta-nerve growth factor; BetaNGF; beta-NGF; bNGF; b-NGF; HSAN5; MGC161426; MGC161428; nerve growth factor; nerve growth factor (beta polypeptide); nerve growth factor, beta; nerve growth factor, beta polypeptide; nerve growth factor, beta subunit; NGF; NGF b; NGF β; Ngfb; NGFbeta; NGFβ; β nerve growth factor; β NGF; βNGF

Gene Symbols:
NGF

Isotype:
IgG1 κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
C1

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01138

Gene ID (Entrez):
4803

Immunogen:
Glu19-Arg239 (Accession P01138), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
NGF

Img

Fischer Scientific

7240990

Mouse Monoclonal Antibody...


Antigen:
Thioredoxin 1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
ADF; ATL-derived factor; AW550880; DKFZp686B1993; MGC61975; RP11-427L11.1; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin; thioredoxin 1; thioredoxin delta 3; TRDX; TRX; TRX1; Txn; TXN delta 3; Txn1

Gene Symbols:
TXN

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
3#

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P10599

Gene ID (Entrez):
7295

Immunogen:
Met1-Val105 (Accession P10599), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
TXN

Img

Fischer Scientific

7240990

Mouse Monoclonal Antibody...


Antigen:
Thioredoxin 1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
ADF; ATL-derived factor; AW550880; DKFZp686B1993; MGC61975; RP11-427L11.1; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin; thioredoxin 1; thioredoxin delta 3; TRDX; TRX; TRX1; Txn; TXN delta 3; Txn1

Gene Symbols:
TXN

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
3#

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P10599

Gene ID (Entrez):
7295

Immunogen:
Met1-Val105 (Accession P10599), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
TXN

Img

Fischer Scientific

7240990

Mouse Monoclonal Antibody...


Antigen:
Thioredoxin 1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Alias:
ADF; ATL-derived factor; AW550880; DKFZp686B1993; MGC61975; RP11-427L11.1; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin; thioredoxin 1; thioredoxin delta 3; TRDX; TRX; TRX1; Txn; TXN delta 3; Txn1

Gene Symbols:
TXN

Isotype:
IgG2a κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
3#

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P10599

Gene ID (Entrez):
7295

Immunogen:
Met1-Val105 (Accession P10599), with N-terminal His Tag

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
TXN