7244927

WISP2 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

WISP2

Applications

ELISA, Western Blot

Conjugate

Biotin

Host Species

Rabbit

Target Species

Human

Gene Accession No.

O76076

Gene ID (Entrez)

8839

Immunogen

E.coli-derived Recombinant Human CTGFL/WISP-2

Purification Method

Antigen affinity chromatography

Gene

CCN5

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

CCN family member 5; CCN family protein COP-1; Ccn5; connective tissue growth factor-like protein; Connective tissue growth factor-related protein 58; Cop1; Crgr4; CT58; CTGFL; CTGF-L; Rcop1; UNQ228/PRO261; WISP2; WISP-2; WNT1 inducible signaling pathway protein 2; WNT1-inducible-signaling pathway protein 2

Gene Symbols

CCN5

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human CTGFL/WISP-2
  • Anti-Human CTGFL/WISP-2-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect hCTGFL/WISP-2 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human CTGFL/WISP-2 (500-P212) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hCTGFL/WISP-2
  • Western Blot: To detect hCTGFL/WISP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant hCTGFL/WISP-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P212BT-1MG will be provided as 2 x 500 μg Wisp2 a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family
  • WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes
  • The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain
  • Wisp2 lacks the CT domain which is implicated in dimerization and heparin binding
  • It is 72% identical to the mouse protein at the amino acid level
  • This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation
  • Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors
  • It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.

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7244927

Rabbit Polyclonal Antibody...


Antigen:
WISP2

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
O76076

Gene ID (Entrez):
8839

Immunogen:
E.coli-derived Recombinant Human CTGFL/WISP-2

Purification Method:
Antigen affinity chromatography

Gene:
CCN5

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
CCN family member 5; CCN family protein COP-1; Ccn5; connective tissue growth factor-like protein; Connective tissue growth factor-related protein 58; Cop1; Crgr4; CT58; CTGFL; CTGF-L; Rcop1; UNQ228/PRO261; WISP2; WISP-2; WNT1 inducible signaling pathway protein 2; WNT1-inducible-signaling pathway protein 2

Gene Symbols:
CCN5

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7244928

Rabbit Polyclonal Antibody...


Antigen:
IL-1 beta

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Rat

Gene Accession No.:
Q63264

Gene ID (Entrez):
24494

Immunogen:
E.coli-derived Recombinant Rat IL-1beta

Purification Method:
Antigen affinity chromatography

Gene:
IL1B

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
__

Gene Symbols:
IL1B

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7244929

Rabbit Polyclonal Antibody...


Antigen:
EGFR

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P00533

Gene ID (Entrez):
1956

Immunogen:
CHO cells-derived Recombinant Human EGF Receptor (EGFR)

Purification Method:
Antigen affinity chromatography

Gene:
EGFR

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
2.7.10.1; 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erbB) oncogene homolog; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2.7.10.1; egf receptor; Egfr; EGFR-related peptide; epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); ERBB; ERBB1; ErbB-1; erb-b2 receptor tyrosine kinase 1; Errb1; Errp; HER1; kinase EGFR; mENA; NISBD2; Oncogene ERBB; PIG61; Proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; Urogastrone; wa2; wa-2; Wa5; waved 2

Gene Symbols:
EGFR

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7244931

Rabbit Polyclonal Antibody...


Antigen:
CXCL1

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P09341

Gene ID (Entrez):
2919

Immunogen:
E.coli-derived Recombinant Human GRO-alpha/MGSA (CXCL1)

Purification Method:
Antigen affinity chromatography

Gene:
Cxcl1

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
alpha-chemokine; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); Cinc1; CINC-1; CXC; CXC motif chemokine; C-X-C motif chemokine 1; C-X-C motif chemokine ligand 1; CXCL; CXCL1; CXCL-1; Cytokine-induced neutrophil chemoattractant 1; fibroblast secretory protein; Fsp; Gro; GRO a; GRO a; Gro1; GRO1 oncogene; GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); GROa; GROalpha; GRO-alpha(1-73); GRO-alpha(4-73); GRO-alpha(5-73); GRO-alpha(6-73); Growth-regulated alpha protein; GROa; Hematopoietic synergistic factor; HSF; KC; KC(5-72); KC/GR)-alpha; KC/GRO-alpha; KC-T; melanoma growth stimulating activity, alpha; Melanoma growth stimulatory activity; melanoma growth stimulatory activity alpha; MGSA; MGSA alpha; MGSA-a; N51; NAP3; NAP-3; Neutrophil-activating protein 3; platelet-derived g

Gene Symbols:
Cxcl1

Primary or Secondary:
Primary

Content And Storage:
-20°C