7245067

FGF2 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

FGF2

Applications

ELISA, Western Blot

Conjugate

Biotin

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P09038

Gene ID (Entrez)

2247

Immunogen

E.coli-derived Recombinant Human FGF-basic (154 a.a.)

Purification Method

Antigen affinity chromatography

Gene

FGF2

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

Basic fibroblast growth factor; basic fibroblast growth factor bFGF; bFGF; FGF; fgf basic; Fgf2; Fgf-2; Fgfb; FGF-b; Fibroblast growth factor; fibroblast growth factor 2; fibroblast growth factor 2 (basic); HBGF-2; Heparin-binding growth factor 2; H-FGF-b-147; H-FGF-b-154; M-FGF-b; Prostatic growth factor; prostatropin

Gene Symbols

FGF2

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human FGF-basic
  • Anti-Human FGF-basic-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect hFGF-basic by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human FGF-basic (500-P18) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hFGF-basic
  • Western Blot: To detect Human FGF-basic by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human FGF-basic is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P18BT-1MG will be provided as 2 x 500 μg FGF2 (FGFb, fibroblast growth factor basic) belongs to the fibroblast growth factor (FGF) family, and interacts with high-affinity transmembrane receptors to influence cell proliferation and tissue neovascularization
  • FGF2 exists as five isoforms with distinct intracellular localizations and functions
  • The 18 kDa isoform is predominantly cytosolic and acts through cell surface receptors, whereas the 22, 22.5, 24 and 34 kDa isoforms are nuclear and may signal independent of transmembrane receptor pathways
  • In humans, the gene is located on the q arm of chromosome 4
  • FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth
  • The mRNA for FGF2 contains multiple polyadenylation sites, and is alternatively translated from non-AUG and AUG initiation codons, resulting in five different isoforms with distinct properties
  • The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF
  • Diseases associated with FGF2 dysfunction include Kaposi Sarcoma and corneal neovascularization.

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Show Difference

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Fischer Scientific

7245067

Rabbit Polyclonal Antibody...


Antigen:
FGF2

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P09038

Gene ID (Entrez):
2247

Immunogen:
E.coli-derived Recombinant Human FGF-basic (154 a.a.)

Purification Method:
Antigen affinity chromatography

Gene:
FGF2

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
Basic fibroblast growth factor; basic fibroblast growth factor bFGF; bFGF; FGF; fgf basic; Fgf2; Fgf-2; Fgfb; FGF-b; Fibroblast growth factor; fibroblast growth factor 2; fibroblast growth factor 2 (basic); HBGF-2; Heparin-binding growth factor 2; H-FGF-b-147; H-FGF-b-154; M-FGF-b; Prostatic growth factor; prostatropin

Gene Symbols:
FGF2

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7245068

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Antigen:
IL-10

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
P18893

Gene ID (Entrez):
16153

Immunogen:
E.coli-derived Recombinant Murine IL-10

Purification Method:
Antigen affinity chromatography

Gene:
IL10

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

Gene Symbols:
IL10

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Antigen:
IL-5

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
P04401

Gene ID (Entrez):
16191

Immunogen:
E.coli-derived Recombinant Murine IL-5

Purification Method:
Antigen affinity chromatography

Gene:
Il5

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF

Gene Symbols:
Il5

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Antigen:
MCP-5

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
Q62401

Gene ID (Entrez):
20293

Immunogen:
E.coli-derived Recombinant Murine MCP-5 (CCL12)

Purification Method:
Antigen affinity chromatography

Gene:
Ccl12

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
C-C motif chemokine 12; Ccl12; chemokine (C-C motif) ligand 12; MCP-1-related chemokine; Mcp5; MCP-5; Monocyte chemoattractant protein 5; monocyte chemotactic protein 5; Scya12; small inducible cytokine A12; small-inducible cytokine A12

Gene Symbols:
Ccl12

Primary or Secondary:
Primary

Content And Storage:
-20°C