7245068

IL-10 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

IL-10

Applications

ELISA, Western Blot

Conjugate

Biotin

Host Species

Rabbit

Target Species

Mouse

Gene Accession No.

P18893

Gene ID (Entrez)

16153

Immunogen

E.coli-derived Recombinant Murine IL-10

Purification Method

Antigen affinity chromatography

Gene

IL10

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

Gene Symbols

IL10

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: MSRGQYSRED NNCTHFPVGQ SHMLLELRTA FSQVKTFFQT KDQLDNILLT DSLMQDFKGY LGCQALSEMI QFYLVEVMPQ AEKHGPEIKE HLNSLGQKLK TLRMRLRRCH RFLPCENKSK AVEQVKSDFN KLEDQGVYKA MNEFDIFINC IEAYMMIKMK S
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine IL-10
  • Anti-Murine IL-10-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect mIL-10 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine IL-10 (500-P60) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant mIL-10
  • Western Blot: To detect mIL-10 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant mIL-10 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P60BT-1MG will be provided as 2 x 500 μg IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes
  • This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages
  • It also enhances B cell survival, proliferation, and antibody production
  • Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway
  • Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract
  • Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis
  • Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.

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7245068

Rabbit Polyclonal Antibody...


Antigen:
IL-10

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
P18893

Gene ID (Entrez):
16153

Immunogen:
E.coli-derived Recombinant Murine IL-10

Purification Method:
Antigen affinity chromatography

Gene:
IL10

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

Gene Symbols:
IL10

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7245069

Rabbit Polyclonal Antibody...


Antigen:
IL-5

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
P04401

Gene ID (Entrez):
16191

Immunogen:
E.coli-derived Recombinant Murine IL-5

Purification Method:
Antigen affinity chromatography

Gene:
Il5

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF

Gene Symbols:
Il5

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Antigen:
MCP-5

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
Q62401

Gene ID (Entrez):
20293

Immunogen:
E.coli-derived Recombinant Murine MCP-5 (CCL12)

Purification Method:
Antigen affinity chromatography

Gene:
Ccl12

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
C-C motif chemokine 12; Ccl12; chemokine (C-C motif) ligand 12; MCP-1-related chemokine; Mcp5; MCP-5; Monocyte chemoattractant protein 5; monocyte chemotactic protein 5; Scya12; small inducible cytokine A12; small-inducible cytokine A12

Gene Symbols:
Ccl12

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Goat Polyclonal Antibody...


Antigen:
MCP-3

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Goat

Target Species:
Human

Gene Accession No.:
P80098

Gene ID (Entrez):
6354

Immunogen:
E.coli-derived Recombinant Human MCP-3 (CCL7)

Purification Method:
Antigen affinity chromatography

Gene:
CCL7

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
C-C motif chemokine 7; C-C motif chemokine ligand 7; CCL7; chemokine (C-C motif) ligand 7; chemotactic protein-3; Fic; H-MCP-3; Intercrine/chemokine MARC; marc; Mcp3; MCP-3; MGC138463; MGC138465; Monocyte chemoattractant protein 3; monocyte chemotactic protein 3; NC28; Protein FIC; RANTES/sis homolog; RP23-350G1.4; SCYA6; Scya7; small inducible cytokine A7; small inducible cytokine A7 (monocyte chemotactic protein 3); small-inducible cytokine A7

Gene Symbols:
CCL7

Primary or Secondary:
Primary

Content And Storage:
-20°C