7245090

CCL5 (RANTES) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CCL5 (RANTES)

Applications

ELISA, Western Blot

Conjugate

Biotin

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P13501

Gene ID (Entrez)

6352

Immunogen

E.coli-derived, 7.8 kDa Recombinant Human RANTES

Purification Method

Antigen affinity chromatography

Gene

CCL5

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

beta-chemokine RANTES; CC chemokine; C-C motif chemokine 5; C-C motif chemokine ligand 5; CCL5; chemokine (C-C motif) ligand 5; D17S136E; EoCP; eosinophil chemotactic cytokine; MGC17164; MuRantes; OTTHUMP00000197106; RANTES; RANTES protein; RANTES(3-68); RANTES(4-68); regulated upon activation normal T-cell expressed and secreted; regulated upon activation, normally T-expressed, and presumably secreted; Scya5; SIS d; SISd; SIS-delta; SISd; small inducible cytokine A5; small inducible cytokine subfamily A (Cys-Cys), member 5; small-inducible cytokine A5; T cell-specific protein P228; T-cell specific protein p288; T-cell-specific protein RANTES; TCP228; Unknown (protein for MGC:127014)

Gene Symbols

CCL5

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human RANTES (CCL5)
  • Anti-Human RANTES (CCL5)-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect hRANTES by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human RANTES (500-P36) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hRANTES
  • Western Blot: To detect hRANTES by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant hRANTES is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P36BT-1MG will be provided as 2 x 500 μg CCL5 (RANTES) is a chemokine gene located on the q-arm of chromosome 17
  • Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes
  • The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide
  • CCL5, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells, and eosinophils
  • It causes the release of histamine from basophils and activates eosinophils
  • This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells
  • It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor
  • Alternative splicing results in multiple transcript variants that encode different isoforms
  • Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.

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Show Difference

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7245090

Rabbit Polyclonal Antibody...


Antigen:
CCL5 (RANTES)

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P13501

Gene ID (Entrez):
6352

Immunogen:
E.coli-derived, 7.8 kDa Recombinant Human RANTES

Purification Method:
Antigen affinity chromatography

Gene:
CCL5

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
beta-chemokine RANTES; CC chemokine; C-C motif chemokine 5; C-C motif chemokine ligand 5; CCL5; chemokine (C-C motif) ligand 5; D17S136E; EoCP; eosinophil chemotactic cytokine; MGC17164; MuRantes; OTTHUMP00000197106; RANTES; RANTES protein; RANTES(3-68); RANTES(4-68); regulated upon activation normal T-cell expressed and secreted; regulated upon activation, normally T-expressed, and presumably secreted; Scya5; SIS d; SISd; SIS-delta; SISd; small inducible cytokine A5; small inducible cytokine subfamily A (Cys-Cys), member 5; small-inducible cytokine A5; T cell-specific protein P228; T-cell specific protein p288; T-cell-specific protein RANTES; TCP228; Unknown (protein for MGC:127014)

Gene Symbols:
CCL5

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Antigen:
Klotho

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9UEF7

Gene ID (Entrez):
9365

Immunogen:
E.coli-derived Recombinant Human Klotho

Purification Method:
Antigen affinity chromatography

Gene:
KL

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
alpha-kl; HFTC3; Kl; Klotho; Klotho peptide; secreted form of Klotho protein

Gene Symbols:
KL

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Antigen:
CCL28

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9NRJ3

Gene ID (Entrez):
56477

Immunogen:
E.coli-derived Recombinant Human MEC (CCL28)

Purification Method:
Antigen affinity chromatography

Gene:
CCL28

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
CC chemokine CCL28; C-C motif chemokine 28; C-C motif chemokine ligand 28; CCK 1; CCK1; CCK1 protein; CCL 28; Ccl28; chemokine (C-C motif) ligand 28; chemokine (C-C motif) ligand 28 splice variant chi; MEC; Mucosae-associated epithelial chemokine; Protein CCK1; SCYA28; small inducible cytokine A28; small inducible cytokine subfamily A (Cys-Cys), member 28; small-inducible cytokine A28

Gene Symbols:
CCL28

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Goat Polyclonal Antibody...


Antigen:
IL-6

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Goat

Target Species:
Human

Gene Accession No.:
P05231

Gene ID (Entrez):
3569

Immunogen:
E.coli-derived Recombinant Human IL-6

Purification Method:
Antigen affinity chromatography

Gene:
Il6

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6

Gene Symbols:
Il6

Primary or Secondary:
Primary

Content And Storage:
-20°C