7245135

TSLP Polyclonal Antibody, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

TSLP

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q969D9

Gene ID (Entrez)

85480

Immunogen

E.coli-derived Recombinant Human TSLP

Purification Method

Antigen affinity chromatography

Gene

TSLP

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

Thymic stroma-derived lymphopoietin; thymic stromal lymphopoietin; TSLP

Gene Symbols

TSLP

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPTAGCASLAKEM FAMKTKAALA IWCPGYSETQ INATQAMKKR RKRKVTTNKC LEQVSQLQGLWRRFNRPLLK QQ
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human TSLP
  • Anti-Human TSLP-specific antibody was purified by affinity chromatography employing an immobilized Human TSLP matrix
  • Sandwich ELISA: To detect Human TSLP by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
  • This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human TSLP (500-P258Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hHuman TSLP
  • Western Blot: To detect Human TSLP by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human TSLP is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain
  • It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c (+) dendritic cells, naive CD4 (+), and CD8 (+) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation
  • TSLP influences the regulation of the positive selection of regulatory T cells and maintenance of peripheral CD4 (+) T cell homeostasis
  • It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis
  • It is expressed in heart, liver and prostate.

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7245135

Rabbit Polyclonal Antibody...


Antigen:
TSLP

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q969D9

Gene ID (Entrez):
85480

Immunogen:
E.coli-derived Recombinant Human TSLP

Purification Method:
Antigen affinity chromatography

Gene:
TSLP

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
Thymic stroma-derived lymphopoietin; thymic stromal lymphopoietin; TSLP

Gene Symbols:
TSLP

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7245137

Mouse Monoclonal Antibody...


Antigen:
Factor VIII

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P00451

Gene ID (Entrez):
2157

Immunogen:
Purified human Factor VIII.

Purification Method:
Protein G

Gene:
F8

Concentration:
1.1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative; pH 7.4

Gene Alias:
AHF; Antihemophilic factor; CF8; Cf-8; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; factor VIII precursor; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7

Gene Symbols:
F8

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

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7245139

Goat Polyclonal Antibody...


Antigen:
IL-12 p70

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Goat

Target Species:
Mouse

Gene Accession No.:
P43431, P43432

Gene ID (Entrez):
16159, 16160

Immunogen:
CHO cells-derived Recombinant Murine IL-12 p70

Purification Method:
Antigen affinity chromatography

Gene:
__

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
20C2; CLMF; CLMF p35; CLMF p40; CLMF2; cytokine; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; Cytotoxic lymphocyte maturation factor 40 kDa subunit; il 12; IL 12p70; Il12; IL-12; Il-12 p35; IL-12 p75; IL-12 subunit p35; IL-12 subunit p40; IL-12, subunit p35; IL12, subunit p40; Il-12; cytokine; IL12A; IL-12A; IL12A/B; IL12AB; IL12B; Il-12b; IL12P35; IL-12p35; Il12p40; Il-12p40; IL35 subunit; ILN; IMD28; IMD29; Interleukin; interleukin 12 35 kDa subunit; interleukin 12 35kDa subunit; interleukin 12 40 kDa subunit; interleukin 12 40kDa subunit; interleukin 12 p35 subunit; interleukin 12 p40 subunit precursor; interleukin 12 polypeptide 35; interleukin 12, p35; interleukin 12, p40; interleukin 12A; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); interleukin 12B; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); interleu

Gene Symbols:
IL12A, Il12b

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7245140

Rabbit Polyclonal Antibody...


Antigen:
CNTF

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P26441

Gene ID (Entrez):
1270

Immunogen:
E.coli-derived Recombinant Human CNTF

Purification Method:
Antigen affinity chromatography

Gene:
CNTF

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AI429687; Ciliary neurotrophic factor; ciliary neurotropic factor; Cntf; HCNTF; H-CNTF

Gene Symbols:
CNTF

Primary or Secondary:
Primary

Content And Storage:
-20°C