7245180
Leptin Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Goat Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Leptin
Applications
ELISA, Western Blot
Conjugate
Biotin
Host Species
Goat
Target Species
Rat
Gene Accession No.
P50596
Gene ID (Entrez)
25608
Immunogen
E.coli-derived Recombinant Rat Leptin
Purification Method
Antigen affinity chromatography
Gene
Lep
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Gene Symbols
Lep
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: MVPIHKVQDD TKTLIKTIVT RINDISHTQS VSARQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQILTSLP SQNVLQIAHD LENLRDLLHL LAFSKSCSLP QTRGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDLSPEC
- Preparation: Produced from sera of goats immunized with highly pure Recombinant Rat Leptin
- Anti-Rat Leptin-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Rat Leptin by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Rat Leptin (500-P185G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Rat Leptin
- Western Blot: To detect Rat Leptin by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant Rat Leptin is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P185GBT-1MG will be provided as 2 x 500 μg Leptin is a 167 amino acid long protein hormone with important effects in regulating body weight, metabolism and reproductive function
- Leptin is approximately 16 kDa in mass and encoded by the obese (ob) gene
- Leptin is expressed predominantly by adipocytes, which fits with the idea that body weight is sensed as the total mass of fat in the body
- Smaller amounts of leptin are also secreted by cells in the epithelium of the stomach and in the placenta
- Leptin receptors are highly expressed in areas of the hypothalamus known to be important in regulating body weight, as well as in T lymphocytes and vascular endothelial cells
- Leptin's effects on body weight are mediated through effects on hypothalamic centers that control feeding behavior and hunger, body temperature and energy expenditure
- Leptin is involved in regulating food intake, energy expenditure, and adiposity through hypothalamic leptin receptors
- Leptin promotes hematopoiesis, angiogenesis, wound healing, inflammation, immune responses, influences pubertal development and fetal growth
- Studies have investigated the role of leptin in obesity, anorexia nervosa, insulin resistance, and hypertension
- Leptin also has thermogenic actions and regulates enzymes of fatty acid oxidation
- Severe hereditary obesity in rodents and humans can be caused by defects in leptin production.
Compare Similar Items
Show Difference
Antigen: Leptin
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Goat
Target Species: Rat
Gene Accession No.: P50596
Gene ID (Entrez): 25608
Immunogen: E.coli-derived Recombinant Rat Leptin
Purification Method: Antigen affinity chromatography
Gene: Lep
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Gene Symbols: Lep
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
Leptin
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Goat
Target Species:
Rat
Gene Accession No.:
P50596
Gene ID (Entrez):
25608
Immunogen:
E.coli-derived Recombinant Rat Leptin
Purification Method:
Antigen affinity chromatography
Gene:
Lep
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Gene Symbols:
Lep
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Gram Negative Endotoxin
Applications: ELISA
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: E. coli serotypes: O:111, B4 J5.
Purification Method: Protein A
Gene: __
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.4
Gene Alias: __
Gene Symbols: __
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Antigen:
Gram Negative Endotoxin
Applications:
ELISA
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
E. coli serotypes: O:111, B4 J5.
Purification Method:
Protein A
Gene:
__
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.4
Gene Alias:
__
Gene Symbols:
__
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Antigen: CCL16
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Human
Gene Accession No.: O15467
Gene ID (Entrez): 6360
Immunogen: E.coli-derived Recombinant Human LEC (CCL16)
Purification Method: Antigen affinity chromatography
Gene: CCL16
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: C-C motif chemokine 16; C-C motif chemokine ligand 16; CCL16; chemokine (C-C motif) ligand 16; Chemokine CC-4; Chemokine LEC; CKb12; HCC-4; IL-10-inducible chemokine; ILINCK; LCC-1; LEC; liver CC chemokine-1; liver-expressed chemokine; LMC; Lymphocyte and monocyte chemoattractant; MGC117051; monotactin-1; MTN-1; NCC4; NCC-4; new CC chemokine 4; SCYA16; SCYL4; small inducible cytokine subfamily A (Cys-Cys), member 16; small-inducible cytokine A16
Gene Symbols: CCL16
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
CCL16
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
O15467
Gene ID (Entrez):
6360
Immunogen:
E.coli-derived Recombinant Human LEC (CCL16)
Purification Method:
Antigen affinity chromatography
Gene:
CCL16
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
C-C motif chemokine 16; C-C motif chemokine ligand 16; CCL16; chemokine (C-C motif) ligand 16; Chemokine CC-4; Chemokine LEC; CKb12; HCC-4; IL-10-inducible chemokine; ILINCK; LCC-1; LEC; liver CC chemokine-1; liver-expressed chemokine; LMC; Lymphocyte and monocyte chemoattractant; MGC117051; monotactin-1; MTN-1; NCC4; NCC-4; new CC chemokine 4; SCYA16; SCYL4; small inducible cytokine subfamily A (Cys-Cys), member 16; small-inducible cytokine A16
Gene Symbols:
CCL16
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Entamoeba histolytica
Applications: ELISA
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Protozoa
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: Entamoeba histolytica HK-9.
Purification Method: Protein A
Gene: __
Concentration: 0.77 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.4
Gene Alias: E. histolytica
Gene Symbols: __
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Antigen:
Entamoeba histolytica
Applications:
ELISA
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Protozoa
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
Entamoeba histolytica HK-9.
Purification Method:
Protein A
Gene:
__
Concentration:
0.77 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.4
Gene Alias:
E. histolytica
Gene Symbols:
__
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles