7245335
Leptin Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Leptin
Applications
ELISA, Western Blot
Conjugate
Biotin
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P41159
Gene ID (Entrez)
3952
Immunogen
E.coli-derived Recombinant Human Leptin
Purification Method
Antigen affinity chromatography
Gene
Lep
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Gene Symbols
Lep
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human Leptin
- Anti-Human Leptin-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Human Leptin by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human Leptin (500-P86) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human Leptin
- Western Blot: To detect hLeptin by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant hLeptin is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P86BT-1MG will be provided as 2 x 500 μg Leptin is a 167 amino acid long protein hormone with important effects in regulating body weight, metabolism and reproductive function
- Leptin is approximately 16 kDa in mass and encoded by the obese (ob) gene
- Leptin is expressed predominantly by adipocytes, which fits with the idea that body weight is sensed as the total mass of fat in the body
- Smaller amounts of leptin are also secreted by cells in the epithelium of the stomach and in the placenta
- Leptin receptors are highly expressed in areas of the hypothalamus known to be important in regulating body weight, as well as in T lymphocytes and vascular endothelial cells
- Leptin's effects on body weight are mediated through effects on hypothalamic centers that control feeding behavior and hunger, body temperature and energy expenditure
- Leptin is involved in regulating food intake, energy expenditure, and adiposity through hypothalamic leptin receptors
- Leptin promotes hematopoiesis, angiogenesis, wound healing, inflammation, immune responses, influences pubertal development and fetal growth
- Studies have investigated the role of leptin in obesity, anorexia nervosa, insulin resistance, and hypertension
- Leptin also has thermogenic actions and regulates enzymes of fatty acid oxidation
- Severe hereditary obesity in rodents and humans can be caused by defects in leptin production.
Compare Similar Items
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Antigen: Leptin
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P41159
Gene ID (Entrez): 3952
Immunogen: E.coli-derived Recombinant Human Leptin
Purification Method: Antigen affinity chromatography
Gene: Lep
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Gene Symbols: Lep
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
Leptin
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P41159
Gene ID (Entrez):
3952
Immunogen:
E.coli-derived Recombinant Human Leptin
Purification Method:
Antigen affinity chromatography
Gene:
Lep
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Gene Symbols:
Lep
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: CXCL6
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: E.coli-derived Recombinant Murine LIX (CXCL6) (92 a.a.)
Purification Method: Antigen affinity chromatography
Gene: __
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 5; chemokine (C-X-C motif) ligand 6; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); chemokine alpha 3; CKA3; CKA-3; CXC; CXC chemokine LIX; CXC motif chemokine; C-X-C motif chemokine 5; C-X-C motif chemokine 6; C-X-C motif chemokine ligand 6; CXCL; Cxcl5; CXCL6; Cytokine LIX; GCP2; GCP-2; granulocyte chemotactic protein 2; Scyb5; SCYB6; small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2); Small inducible cytokine subfamily B (Cys-X-Cys), member b; small-inducible cytokine B5; Small-inducible cytokine B6; Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3
Gene Symbols: __
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
CXCL6
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
E.coli-derived Recombinant Murine LIX (CXCL6) (92 a.a.)
Purification Method:
Antigen affinity chromatography
Gene:
__
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 5; chemokine (C-X-C motif) ligand 6; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); chemokine alpha 3; CKA3; CKA-3; CXC; CXC chemokine LIX; CXC motif chemokine; C-X-C motif chemokine 5; C-X-C motif chemokine 6; C-X-C motif chemokine ligand 6; CXCL; Cxcl5; CXCL6; Cytokine LIX; GCP2; GCP-2; granulocyte chemotactic protein 2; Scyb5; SCYB6; small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2); Small inducible cytokine subfamily B (Cys-X-Cys), member b; small-inducible cytokine B5; Small-inducible cytokine B6; Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3
Gene Symbols:
__
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Neutrophil elastase
Applications: ELISA
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P08246
Gene ID (Entrez): 1991
Immunogen: Purified human Neutrophil Elastase.
Purification Method: Protein A
Gene: ELANE
Concentration: 0.91 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.4
Gene Alias: bone marrow serine protease; ELA2; ELA2A; ELANE; Elastase; elastase 2, neutrophil; elastase, neutrophil expressed; Elastase2; elastase-2; F430011M15Rik; GE; granulocyte-derived elastase; HLE; HNE; Human leukocyte elastase; Leukocyte elastase; medullasin; NE; neutrophil elastase; PE-1; PMN elastase; PMN-E; polymorphonuclear elastase; SCN1; serine protease
Gene Symbols: ELANE
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Antigen:
Neutrophil elastase
Applications:
ELISA
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P08246
Gene ID (Entrez):
1991
Immunogen:
Purified human Neutrophil Elastase.
Purification Method:
Protein A
Gene:
ELANE
Concentration:
0.91 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.4
Gene Alias:
bone marrow serine protease; ELA2; ELA2A; ELANE; Elastase; elastase 2, neutrophil; elastase, neutrophil expressed; Elastase2; elastase-2; F430011M15Rik; GE; granulocyte-derived elastase; HLE; HNE; Human leukocyte elastase; Leukocyte elastase; medullasin; NE; neutrophil elastase; PE-1; PMN elastase; PMN-E; polymorphonuclear elastase; SCN1; serine protease
Gene Symbols:
ELANE
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Antigen: IL-17A
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q16552
Gene ID (Entrez): 3605
Immunogen: E.coli-derived Recombinant Human IL-17A
Purification Method: Antigen affinity chromatography
Gene: IL17A
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A
Gene Symbols: IL17A
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IL-17A
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q16552
Gene ID (Entrez):
3605
Immunogen:
E.coli-derived Recombinant Human IL-17A
Purification Method:
Antigen affinity chromatography
Gene:
IL17A
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A
Gene Symbols:
IL17A
Primary or Secondary:
Primary
Content And Storage:
-20°C