7245341
IL-17A Polyclonal Antibody, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
IL-17A
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q16552
Gene ID (Entrez)
3605
Immunogen
E.coli-derived Recombinant Human IL-17A
Purification Method
Antigen affinity chromatography
Gene
IL17A
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A
Gene Symbols
IL17A
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IL-17A
- Anti-Human IL-17A-specific antibody was purified by affinity chromatography employing an immobilized Human IL-17 matrix
- Sandwich ELISA: To detect Human IL-17A by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
- This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human IL-17A (500-P07Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human IL-17A
- Western Blot: To detect Human IL-17A by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human IL-17A is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection
- IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217)
- High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts
- In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2
- In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils
- Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor
- IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).
Compare Similar Items
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Antigen: IL-17A
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q16552
Gene ID (Entrez): 3605
Immunogen: E.coli-derived Recombinant Human IL-17A
Purification Method: Antigen affinity chromatography
Gene: IL17A
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A
Gene Symbols: IL17A
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IL-17A
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q16552
Gene ID (Entrez):
3605
Immunogen:
E.coli-derived Recombinant Human IL-17A
Purification Method:
Antigen affinity chromatography
Gene:
IL17A
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A
Gene Symbols:
IL17A
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: MIP-1 delta
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Goat
Target Species: Human
Gene Accession No.: Q16663
Gene ID (Entrez): 6359
Immunogen: E.coli-derived, 10.1 kDa Recombinant Human MIP-5 (CCL15)
Purification Method: Antigen affinity chromatography
Gene: CCL15
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: C-C motif chemokine 15; C-C motif chemokine ligand 15; CCL15; CCL15(22-92); CCL15(25-92); CCL15(29-92); chemokine (C-C motif) ligand 15; chemokine CC-2; HCC-2; HCC-2Lkn-1; HMRP-2B; leukotactin 1; Leukotactin-1; LKN1; LKN-1; Macrophage inflammatory protein 5; MIP-1 delta; MIP-1D; MIP5; MIP-5; MIP-5MIP-1d; Mrp-2b; NCC3; NCC-3; NCC-3MIP-1D; NCC3MRP-2B; new CC chemokine 3; SCYA15; SCYA15member 15; SCYL3; small inducible cytokine subfamily A (Cys-Cys), member 15; small-inducible cytokine A15; SY15
Gene Symbols: CCL15
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
MIP-1 delta
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
Q16663
Gene ID (Entrez):
6359
Immunogen:
E.coli-derived, 10.1 kDa Recombinant Human MIP-5 (CCL15)
Purification Method:
Antigen affinity chromatography
Gene:
CCL15
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
C-C motif chemokine 15; C-C motif chemokine ligand 15; CCL15; CCL15(22-92); CCL15(25-92); CCL15(29-92); chemokine (C-C motif) ligand 15; chemokine CC-2; HCC-2; HCC-2Lkn-1; HMRP-2B; leukotactin 1; Leukotactin-1; LKN1; LKN-1; Macrophage inflammatory protein 5; MIP-1 delta; MIP-1D; MIP5; MIP-5; MIP-5MIP-1d; Mrp-2b; NCC3; NCC-3; NCC-3MIP-1D; NCC3MRP-2B; new CC chemokine 3; SCYA15; SCYA15member 15; SCYL3; small inducible cytokine subfamily A (Cys-Cys), member 15; small-inducible cytokine A15; SY15
Gene Symbols:
CCL15
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Epo
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P01588
Gene ID (Entrez): 2056
Immunogen: CHO cells-derived Recombinant Human EPO
Purification Method: Antigen affinity chromatography
Gene: EPO
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2
Gene Symbols: EPO
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
Epo
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P01588
Gene ID (Entrez):
2056
Immunogen:
CHO cells-derived Recombinant Human EPO
Purification Method:
Antigen affinity chromatography
Gene:
EPO
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2
Gene Symbols:
EPO
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: NTF4
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Human
Gene Accession No.: P34130
Gene ID (Entrez): 4909
Immunogen: E.coli-derived Recombinant Human NT-4
Purification Method: Antigen affinity chromatography
Gene: NTF4
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: __
Gene Symbols: NTF4
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
NTF4
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
P34130
Gene ID (Entrez):
4909
Immunogen:
E.coli-derived Recombinant Human NT-4
Purification Method:
Antigen affinity chromatography
Gene:
NTF4
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
__
Gene Symbols:
NTF4
Primary or Secondary:
Primary
Content And Storage:
-20°C