7245626
IL-17A Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
IL-17A
Applications
ELISA, Western Blot
Conjugate
Biotin
Host Species
Rabbit
Target Species
Mouse
Gene Accession No.
Q62386
Gene ID (Entrez)
16171
Immunogen
E.coli-derived Recombinant Murine IL-17A
Purification Method
Antigen affinity chromatography
Gene
IL17A
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A
Gene Symbols
IL17A
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: AAIIPQSSAC PNTEAKDFLQ NVKVNLKVFN SLGAKVSSRR PSDYLNRSTS PWTLHRNEDP DRYPSVIWEA QCRHQRCVNA EGKLDHHMNS VLIQQEILVL KREPESCPFT FRVEKMLVGV GCTCVASIVR QAA
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine IL-17A
- Anti-Murine IL-17A-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect mIL-17A by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine IL-17A (500-P265) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant mIL-17A
- Western Blot: To detect mIL-17A by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant mIL-17A is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P265BT-1MG will be provided as 2 x 500 μg Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection
- IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217)
- High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts
- In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2
- In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils
- Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor
- IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).
Compare Similar Items
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Antigen: IL-17A
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: Q62386
Gene ID (Entrez): 16171
Immunogen: E.coli-derived Recombinant Murine IL-17A
Purification Method: Antigen affinity chromatography
Gene: IL17A
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A
Gene Symbols: IL17A
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IL-17A
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
Q62386
Gene ID (Entrez):
16171
Immunogen:
E.coli-derived Recombinant Murine IL-17A
Purification Method:
Antigen affinity chromatography
Gene:
IL17A
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
Ctla8; CTLA-8; cytokine; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; Il17; IL-17; IL17A; IL-17a; ILN; Interleukin; interleukin 17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17 precursor; interleukin 17A; interleukin-17; Interleukin17A; interleukin-17A; R-IL-17-A
Gene Symbols:
IL17A
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: FGF9
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: P54130
Gene ID (Entrez): 14180
Immunogen: E.coli-derived Recombinant Murine FGF-9
Purification Method: Antigen affinity chromatography
Gene: FGF9
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: Eks; elbow knee synostosis; FGF; Fgf9; FGF-9; Fibroblast growth factor; Fibroblast growth factor 9; fibroblast growth factor 9 (glia-activating factor); GAF; glia activating factor; glia-activating factor; HBFG-9; HBGF-9; Heparin-binding growth factor 9; M-FGF-9; SYNS3
Gene Symbols: FGF9
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
FGF9
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
P54130
Gene ID (Entrez):
14180
Immunogen:
E.coli-derived Recombinant Murine FGF-9
Purification Method:
Antigen affinity chromatography
Gene:
FGF9
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
Eks; elbow knee synostosis; FGF; Fgf9; FGF-9; Fibroblast growth factor; Fibroblast growth factor 9; fibroblast growth factor 9 (glia-activating factor); GAF; glia activating factor; glia-activating factor; HBFG-9; HBGF-9; Heparin-binding growth factor 9; M-FGF-9; SYNS3
Gene Symbols:
FGF9
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: IGFBP7
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q16270
Gene ID (Entrez): 3490
Immunogen: E.coli-derived Recombinant Human IGF-BP7
Purification Method: Antigen affinity chromatography
Gene: IGFBP7
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: AGM; angiomodulin; FSTL2; IBP7; IBP-7; IGF-binding protein 7; IGFBP; IGFBP rP1; Igfbp7; IGFBP-7; IGFBP-7v; IGFBPRP1; IGFBP-rP1; Insulin like growth factor binding protein; insulin like growth factor binding protein 7; insulin-like growth factor binding protein 7; insulin-like growth factor-binding protein 7; Mac25; MAC25 protein; PGI2-stimulating factor; prostacyclin-stimulating factor; PSF; RAMSVPS; TAF; Tumor-derived adhesion factor
Gene Symbols: IGFBP7
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IGFBP7
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q16270
Gene ID (Entrez):
3490
Immunogen:
E.coli-derived Recombinant Human IGF-BP7
Purification Method:
Antigen affinity chromatography
Gene:
IGFBP7
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
AGM; angiomodulin; FSTL2; IBP7; IBP-7; IGF-binding protein 7; IGFBP; IGFBP rP1; Igfbp7; IGFBP-7; IGFBP-7v; IGFBPRP1; IGFBP-rP1; Insulin like growth factor binding protein; insulin like growth factor binding protein 7; insulin-like growth factor binding protein 7; insulin-like growth factor-binding protein 7; Mac25; MAC25 protein; PGI2-stimulating factor; prostacyclin-stimulating factor; PSF; RAMSVPS; TAF; Tumor-derived adhesion factor
Gene Symbols:
IGFBP7
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: IGFBP7
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q16270
Gene ID (Entrez): 3490
Immunogen: E.coli-derived Recombinant Human IGF-BP7
Purification Method: Antigen affinity chromatography
Gene: IGFBP7
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: AGM; angiomodulin; FSTL2; IBP7; IBP-7; IGF-binding protein 7; IGFBP; IGFBP rP1; Igfbp7; IGFBP-7; IGFBP-7v; IGFBPRP1; IGFBP-rP1; Insulin like growth factor binding protein; insulin like growth factor binding protein 7; insulin-like growth factor binding protein 7; insulin-like growth factor-binding protein 7; Mac25; MAC25 protein; PGI2-stimulating factor; prostacyclin-stimulating factor; PSF; RAMSVPS; TAF; Tumor-derived adhesion factor
Gene Symbols: IGFBP7
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IGFBP7
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q16270
Gene ID (Entrez):
3490
Immunogen:
E.coli-derived Recombinant Human IGF-BP7
Purification Method:
Antigen affinity chromatography
Gene:
IGFBP7
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
AGM; angiomodulin; FSTL2; IBP7; IBP-7; IGF-binding protein 7; IGFBP; IGFBP rP1; Igfbp7; IGFBP-7; IGFBP-7v; IGFBPRP1; IGFBP-rP1; Insulin like growth factor binding protein; insulin like growth factor binding protein 7; insulin-like growth factor binding protein 7; insulin-like growth factor-binding protein 7; Mac25; MAC25 protein; PGI2-stimulating factor; prostacyclin-stimulating factor; PSF; RAMSVPS; TAF; Tumor-derived adhesion factor
Gene Symbols:
IGFBP7
Primary or Secondary:
Primary
Content And Storage:
-20°C