7245253
IL18BP Polyclonal Antibody, PeproTech®, Invitrogen™
Goat Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
IL18BP
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Host Species
Goat
Target Species
Mouse
Gene Accession No.
Q9Z0M9
Gene ID (Entrez)
16068
Immunogen
E.coli-derived Recombinant Murine IL-18BP
Purification Method
Antigen affinity chromatography
Gene
IL18BP
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
Igifbp; Il18bp; IL-18BP; IL18BPa; interferon gamma inducing factor binding protein; interferon gamma-inducing factor-binding protein; interleukin 18 binding protein; interleukin-18 binding protein; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; MC54L; Tadekinig-alfa
Gene Symbols
IL18BP
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- Preparation: Produced from sera of goats immunized with highly pure Recombinant Murine IL-18BP
- Anti-Murine IL-18BP-specific antibody was purified by affinity chromatography employing an immobilized Murine IL-18BP matrix
- Sandwich ELISA: To detect Murine IL-18BP by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
- This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Murine IL-18BP (500-P153GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine IL-18BP
- Western Blot: To detect Murine IL-18BP by Western Blot analysis this antibody can be used at a concentration of 0.1- 0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine IL-18BP is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- Interleukin-18 binding protein (IL-18BP) is a constitutively secreted glycoprotein that acts as a natural antagonist for interleukin-18 (IL-18) by preventing interaction between IL-18 and its receptors
- Through this binding, IL-18BP neutralizes the proinflammatory role of IL-18 in cell-mediated immune responses, resulting in reduced IFN-gamma production by T helper type I cells and inhibition of allospecific cytotoxic T lymphocyte (CTL) activity through augmented natural killer (NK) cell cytotoxicity
- As an inhibitor of IL-18 and an essential component of skin homeostasis, IL-18BP has been linked to a variety of diseases, including eczema, asthma, and the autoimmune condition, Crohn's disease
- The upregulation of IL-18BP by keratinocytes expressing the human papillomavirus (HPV) E7 oncoprotein has been shown to decrease IL-18-induced IFN-gamma production and IL-18-mediated T cell activation
- Elevated levels of IL-18 and IL-18BP, as well as proinflammatory cytokines IFN-gamma, TNF-alpha, IL-1beta and IL-8, have been linked to chronic inflammation and observed in macrophages (including Kupffer cells) isolated from lesions and intestinal tissues of Crohn's disease patients
- As a member of the immunoglobulin-like class of receptors, IL-18BP contains a single immunoglobulin (Ig) domain; although two (b and d) of the four identified human isoforms (a-d) contain incomplete domains that greatly reduce their binding affinity.
Compare Similar Items
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Antigen: IL18BP
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Mouse
Gene Accession No.: Q9Z0M9
Gene ID (Entrez): 16068
Immunogen: E.coli-derived Recombinant Murine IL-18BP
Purification Method: Antigen affinity chromatography
Gene: IL18BP
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: Igifbp; Il18bp; IL-18BP; IL18BPa; interferon gamma inducing factor binding protein; interferon gamma-inducing factor-binding protein; interleukin 18 binding protein; interleukin-18 binding protein; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; MC54L; Tadekinig-alfa
Gene Symbols: IL18BP
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IL18BP
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Mouse
Gene Accession No.:
Q9Z0M9
Gene ID (Entrez):
16068
Immunogen:
E.coli-derived Recombinant Murine IL-18BP
Purification Method:
Antigen affinity chromatography
Gene:
IL18BP
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
Igifbp; Il18bp; IL-18BP; IL18BPa; interferon gamma inducing factor binding protein; interferon gamma-inducing factor-binding protein; interleukin 18 binding protein; interleukin-18 binding protein; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; MC54L; Tadekinig-alfa
Gene Symbols:
IL18BP
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: RANK (soluble)
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9Y6Q6
Gene ID (Entrez): 8792
Immunogen: E.coli-derived Recombinant Human sRANK Receptor
Purification Method: Antigen affinity chromatography
Gene: TNFRSF11A
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: CD265; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; Ly109; mRANK; ODFR; OFE; OPTB7; Osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; Rank; receptor activator of NF-kappaB; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; RGD1563614; TNF receptor superfamily member 11a; Tnfrsf11a; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Gene Symbols: TNFRSF11A
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
RANK (soluble)
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9Y6Q6
Gene ID (Entrez):
8792
Immunogen:
E.coli-derived Recombinant Human sRANK Receptor
Purification Method:
Antigen affinity chromatography
Gene:
TNFRSF11A
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
CD265; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; Ly109; mRANK; ODFR; OFE; OPTB7; Osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; Rank; receptor activator of NF-kappaB; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; RGD1563614; TNF receptor superfamily member 11a; Tnfrsf11a; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Gene Symbols:
TNFRSF11A
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: SCF
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: P20826
Gene ID (Entrez): 17311
Immunogen: E.coli-derived, 18.3 kDa Recombinant Murine SCF
Purification Method: Antigen affinity chromatography
Gene: Kitl
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: 710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Gene Symbols: Kitl
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
SCF
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
P20826
Gene ID (Entrez):
17311
Immunogen:
E.coli-derived, 18.3 kDa Recombinant Murine SCF
Purification Method:
Antigen affinity chromatography
Gene:
Kitl
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Gene Symbols:
Kitl
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: SCF
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: P20826
Gene ID (Entrez): 17311
Immunogen: E.coli-derived, 18.3 kDa Recombinant Murine SCF
Purification Method: Antigen affinity chromatography
Gene: Kitl
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: 710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Gene Symbols: Kitl
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
SCF
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
P20826
Gene ID (Entrez):
17311
Immunogen:
E.coli-derived, 18.3 kDa Recombinant Murine SCF
Purification Method:
Antigen affinity chromatography
Gene:
Kitl
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Gene Symbols:
Kitl
Primary or Secondary:
Primary
Content And Storage:
-20°C