7245195
IL18BP Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Goat Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
IL18BP
Applications
ELISA, Western Blot
Conjugate
Biotin
Host Species
Goat
Target Species
Mouse
Gene Accession No.
Q9Z0M9
Gene ID (Entrez)
16068
Immunogen
E.coli-derived Recombinant Murine IL-18BP
Purification Method
Antigen affinity chromatography
Gene
IL18BP
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
Igifbp; Il18bp; IL-18BP; IL18BPa; interferon gamma inducing factor binding protein; interferon gamma-inducing factor-binding protein; interleukin 18 binding protein; interleukin-18 binding protein; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; MC54L; Tadekinig-alfa
Gene Symbols
IL18BP
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- Preparation: Produced from sera of goats immunized with highly pure Recombinant Murine IL-18BP
- Anti-Murine IL-18BP-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Murine IL-18BP by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine IL-18BP (500-P153G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine IL-18BP
- Western Blot: To detect mIL-18BP by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant mIL-18BP is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P153GBT-1MG will be provided as 2 x 500 μg Interleukin-18 binding protein (IL-18BP) is a constitutively secreted glycoprotein that acts as a natural antagonist for interleukin-18 (IL-18) by preventing interaction between IL-18 and its receptors
- Through this binding, IL-18BP neutralizes the proinflammatory role of IL-18 in cell-mediated immune responses, resulting in reduced IFN-gamma production by T helper type I cells and inhibition of allospecific cytotoxic T lymphocyte (CTL) activity through augmented natural killer (NK) cell cytotoxicity
- As an inhibitor of IL-18 and an essential component of skin homeostasis, IL-18BP has been linked to a variety of diseases, including eczema, asthma, and the autoimmune condition, Crohn's disease
- The upregulation of IL-18BP by keratinocytes expressing the human papillomavirus (HPV) E7 oncoprotein has been shown to decrease IL-18-induced IFN-gamma production and IL-18-mediated T cell activation
- Elevated levels of IL-18 and IL-18BP, as well as proinflammatory cytokines IFN-gamma, TNF-alpha, IL-1beta and IL-8, have been linked to chronic inflammation and observed in macrophages (including Kupffer cells) isolated from lesions and intestinal tissues of Crohn's disease patients
- As a member of the immunoglobulin-like class of receptors, IL-18BP contains a single immunoglobulin (Ig) domain; although two (b and d) of the four identified human isoforms (a-d) contain incomplete domains that greatly reduce their binding affinity.
Compare Similar Items
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Antigen: IL18BP
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Goat
Target Species: Mouse
Gene Accession No.: Q9Z0M9
Gene ID (Entrez): 16068
Immunogen: E.coli-derived Recombinant Murine IL-18BP
Purification Method: Antigen affinity chromatography
Gene: IL18BP
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: Igifbp; Il18bp; IL-18BP; IL18BPa; interferon gamma inducing factor binding protein; interferon gamma-inducing factor-binding protein; interleukin 18 binding protein; interleukin-18 binding protein; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; MC54L; Tadekinig-alfa
Gene Symbols: IL18BP
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IL18BP
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Goat
Target Species:
Mouse
Gene Accession No.:
Q9Z0M9
Gene ID (Entrez):
16068
Immunogen:
E.coli-derived Recombinant Murine IL-18BP
Purification Method:
Antigen affinity chromatography
Gene:
IL18BP
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
Igifbp; Il18bp; IL-18BP; IL18BPa; interferon gamma inducing factor binding protein; interferon gamma-inducing factor-binding protein; interleukin 18 binding protein; interleukin-18 binding protein; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; MC54L; Tadekinig-alfa
Gene Symbols:
IL18BP
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: FGF4
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P08620
Gene ID (Entrez): 2249
Immunogen: E.coli-derived Recombinant Human FGF-4
Purification Method: Antigen affinity chromatography
Gene: Fgf4
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: FGF; FGF4; Fgf-4; Fgfk; Fibroblast growth factor; fibroblast growth factor 4; fibroblast growth factor 4 splice isoform; HBGF-4; heparin secretory transforming protein 1; heparin secretory-transforming protein 1; heparin-binding growth factor 1; heparin-binding growth factor 4; HST; Hst1; hst-1; HSTF1; HSTF-1; human stomach cancer, transforming factor from FGF-related oncogene; kaposi sarcoma oncogene; Kfgf; K-FGF; K-fibroblast growth factor; KS3; oncogene HST; transforming protein KS3
Gene Symbols: Fgf4
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
FGF4
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P08620
Gene ID (Entrez):
2249
Immunogen:
E.coli-derived Recombinant Human FGF-4
Purification Method:
Antigen affinity chromatography
Gene:
Fgf4
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
FGF; FGF4; Fgf-4; Fgfk; Fibroblast growth factor; fibroblast growth factor 4; fibroblast growth factor 4 splice isoform; HBGF-4; heparin secretory transforming protein 1; heparin secretory-transforming protein 1; heparin-binding growth factor 1; heparin-binding growth factor 4; HST; Hst1; hst-1; HSTF1; HSTF-1; human stomach cancer, transforming factor from FGF-related oncogene; kaposi sarcoma oncogene; Kfgf; K-FGF; K-fibroblast growth factor; KS3; oncogene HST; transforming protein KS3
Gene Symbols:
Fgf4
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Resistin
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Human
Gene Accession No.: Q9HD89
Gene ID (Entrez): 56729
Immunogen: E.coli-derived Recombinant Human Resistin
Purification Method: Antigen affinity chromatography
Gene: RETN
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: Adipose tissue specific secretory factor; adipose tissue-specific secretory factor; Adipose-specific cysteine-rich secreted protein A12-alpha; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; cysteine-r; Cysteine-rich secreted protein A12-alpha-like 2; cysteine-rich secreted protein FIZZ3; dominant inhibitory adipocyte-specific secretory factor; dri; FIZZ3; found in inflammatory zone 3; HXCP1; MGC126603; MGC126609; Resistin; resistin delta2; RETN; RETN1; RSN; RSTN; UNQ407/PRO1199; XCP1; Xcp4
Gene Symbols: RETN
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
Resistin
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
Q9HD89
Gene ID (Entrez):
56729
Immunogen:
E.coli-derived Recombinant Human Resistin
Purification Method:
Antigen affinity chromatography
Gene:
RETN
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
Adipose tissue specific secretory factor; adipose tissue-specific secretory factor; Adipose-specific cysteine-rich secreted protein A12-alpha; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; cysteine-r; Cysteine-rich secreted protein A12-alpha-like 2; cysteine-rich secreted protein FIZZ3; dominant inhibitory adipocyte-specific secretory factor; dri; FIZZ3; found in inflammatory zone 3; HXCP1; MGC126603; MGC126609; Resistin; resistin delta2; RETN; RETN1; RSN; RSTN; UNQ407/PRO1199; XCP1; Xcp4
Gene Symbols:
RETN
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: CD127
Applications: Flow Cytometry
Conjugate: Brilliant Violet 711
Host Species: Rat
Target Species: Mouse
Gene Accession No.: P16872
Gene ID (Entrez): 16197
Immunogen: __
Purification Method: Affinity chromatography
Gene: Il7r
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias: CD127; CD127 antigen; CDW127; IL 7 receptor; IL 7R a; IL 7R subunit alpha; IL 7R a; IL 7Ra; IL 7Ra; IL7 receptor; IL-7 receptor alpha chain; IL7 receptor subunit alpha; IL-7 receptor subunit alpha; IL7R; IL-7R; IL7R a; IL7R alpha; IL7R subunit alpha; IL-7R subunit alpha; IL7R a; IL7RA; IL-7RA; IL-7Ralpha; IL-7R-alpha; IL7Ra; ILRA; interleukin 7 receptor; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; Interleukin7 receptor subunit alpha; interleukin-7 receptor subunit alpha; MGC107557; sCD127; soluble IL 7 receptor; soluble IL 7R
Gene Symbols: Il7r
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Antigen:
CD127
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 711
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
P16872
Gene ID (Entrez):
16197
Immunogen:
__
Purification Method:
Affinity chromatography
Gene:
Il7r
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
CD127; CD127 antigen; CDW127; IL 7 receptor; IL 7R a; IL 7R subunit alpha; IL 7R a; IL 7Ra; IL 7Ra; IL7 receptor; IL-7 receptor alpha chain; IL7 receptor subunit alpha; IL-7 receptor subunit alpha; IL7R; IL-7R; IL7R a; IL7R alpha; IL7R subunit alpha; IL-7R subunit alpha; IL7R a; IL7RA; IL-7RA; IL-7Ralpha; IL-7R-alpha; IL7Ra; ILRA; interleukin 7 receptor; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; Interleukin7 receptor subunit alpha; interleukin-7 receptor subunit alpha; MGC107557; sCD127; soluble IL 7 receptor; soluble IL 7R
Gene Symbols:
Il7r
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!