7245197

Resistin Polyclonal Antibody, PeproTech®, Invitrogen™

Goat Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Resistin

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Host Species

Goat

Target Species

Human

Gene Accession No.

Q9HD89

Gene ID (Entrez)

56729

Immunogen

E.coli-derived Recombinant Human Resistin

Purification Method

Antigen affinity chromatography

Gene

RETN

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

Adipose tissue specific secretory factor; adipose tissue-specific secretory factor; Adipose-specific cysteine-rich secreted protein A12-alpha; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; cysteine-r; Cysteine-rich secreted protein A12-alpha-like 2; cysteine-rich secreted protein FIZZ3; dominant inhibitory adipocyte-specific secretory factor; dri; FIZZ3; found in inflammatory zone 3; HXCP1; MGC126603; MGC126609; Resistin; resistin delta2; RETN; RETN1; RSN; RSTN; UNQ407/PRO1199; XCP1; Xcp4

Gene Symbols

RETN

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: SSKTLCSMEE AINERIQEVA GSLIFRAISS IGLECQSVTS RGDLATCPRG FAVTGCTCGS ACGSWDVRAE TTCHCQCAGM DWTGARCCRV QP
  • Preparation: Produced from sera of goats immunized with highly pure Recombinant Human Resistin
  • Anti-Human Resistin-specific antibody was purified by affinity chromatography employing an immobilized Human Resistin matrix
  • Sandwich ELISA: To detect Human Resistin by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
  • This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human Resistin (500-P183GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human Resistin
  • Western Blot: To detect Human Resistin by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human Resistin is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • Adipose tissue is an energy reserve in animals and is strictly regulated
  • Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), perilipin, and resistin
  • Resistin, also known as Adipocyte Secreted Factor (ADSF) and FIZZ3, is a cytokine that is specifically secreted by adipocytes
  • While the function of resistin is not well understood, it appears to have key paracrine roles and has a suggested role in type 2 diabetes
  • Studies show that in obese, diabetic mice the levels of serum resistin are increased, which has an antagonistic effect on insulin
  • Additional studies have shown that resistin causes insulin resistance and glucose intolerance in mice
  • Resistin gene expression requires C/EBP alpha, which is necessary and sufficient for expression
  • Studies show that the coactivators CBP and p300, which have been shown to display histone acetyltransferase (HAT) activity, abundantly acetylate the histones at the resistin promoter suggesting their role in activating chromatin for resistin transcription
  • Numerous PPAR gamma and RXR ligands have been shown to downregulate resistin expression in adipocytes.

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Fischer Scientific

7245197

Goat Polyclonal Antibody...


Antigen:
Resistin

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Goat

Target Species:
Human

Gene Accession No.:
Q9HD89

Gene ID (Entrez):
56729

Immunogen:
E.coli-derived Recombinant Human Resistin

Purification Method:
Antigen affinity chromatography

Gene:
RETN

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
Adipose tissue specific secretory factor; adipose tissue-specific secretory factor; Adipose-specific cysteine-rich secreted protein A12-alpha; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; cysteine-r; Cysteine-rich secreted protein A12-alpha-like 2; cysteine-rich secreted protein FIZZ3; dominant inhibitory adipocyte-specific secretory factor; dri; FIZZ3; found in inflammatory zone 3; HXCP1; MGC126603; MGC126609; Resistin; resistin delta2; RETN; RETN1; RSN; RSTN; UNQ407/PRO1199; XCP1; Xcp4

Gene Symbols:
RETN

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7245199

Rat Monoclonal Antibody...


Antigen:
CD127

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 711

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P16872

Gene ID (Entrez):
16197

Immunogen:
__

Purification Method:
Affinity chromatography

Gene:
Il7r

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
CD127; CD127 antigen; CDW127; IL 7 receptor; IL 7R a; IL 7R subunit alpha; IL 7R a; IL 7Ra; IL 7Ra; IL7 receptor; IL-7 receptor alpha chain; IL7 receptor subunit alpha; IL-7 receptor subunit alpha; IL7R; IL-7R; IL7R a; IL7R alpha; IL7R subunit alpha; IL-7R subunit alpha; IL7R a; IL7RA; IL-7RA; IL-7Ralpha; IL-7R-alpha; IL7Ra; ILRA; interleukin 7 receptor; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; Interleukin7 receptor subunit alpha; interleukin-7 receptor subunit alpha; MGC107557; sCD127; soluble IL 7 receptor; soluble IL 7R

Gene Symbols:
Il7r

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

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7245200

Rabbit Polyclonal Antibody...


Antigen:
IL-7

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P13232

Gene ID (Entrez):
3574

Immunogen:
E.coli-derived Recombinant Human IL-7

Purification Method:
Antigen affinity chromatography

Gene:
Il7

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
A630026I06Rik; H-IL-7; hlb368; IL7; Il-7; ILN; Interleukin; interleukin 7; Interleukin7; interleukin-7; M-IL-7

Gene Symbols:
Il7

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7245201

Rabbit Polyclonal Antibody...


Antigen:
EGF

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P01133

Gene ID (Entrez):
1950

Immunogen:
E.coli-derived Recombinant Human EGF

Purification Method:
Antigen affinity chromatography

Gene:
EGF

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AI790464; beta-urogastrone; EGF; Epidermal growth factor; epidermal growth factor (beta-urogastrone); epidermal growth factor precursor; H-EGF; HOMG4; Pro-epidermal growth factor; Pro-epidermal growth factor precursor (EGF); sb:eu639; URG; Urogastrone

Gene Symbols:
EGF

Primary or Secondary:
Primary

Content And Storage:
-20°C