7245498

Resistin Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Goat Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Resistin

Applications

ELISA, Western Blot

Conjugate

Biotin

Host Species

Goat

Target Species

Human

Gene Accession No.

Q9HD89

Gene ID (Entrez)

56729

Immunogen

E.coli-derived Recombinant Human Resistin

Purification Method

Antigen affinity chromatography

Gene

RETN

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

Adipose tissue specific secretory factor; adipose tissue-specific secretory factor; Adipose-specific cysteine-rich secreted protein A12-alpha; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; cysteine-r; Cysteine-rich secreted protein A12-alpha-like 2; cysteine-rich secreted protein FIZZ3; dominant inhibitory adipocyte-specific secretory factor; dri; FIZZ3; found in inflammatory zone 3; HXCP1; MGC126603; MGC126609; Resistin; resistin delta2; RETN; RETN1; RSN; RSTN; UNQ407/PRO1199; XCP1; Xcp4

Gene Symbols

RETN

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: SSKTLCSMEE AINERIQEVA GSLIFRAISS IGLECQSVTS RGDLATCPRG FAVTGCTCGS ACGSWDVRAE TTCHCQCAGM DWTGARCCRV QP
  • Preparation: Produced from sera of goats immunized with highly pure Recombinant Human Resistin
  • Anti-Human Resistin-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect hResistin by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human Resistin (500-P183G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hResistin
  • Western Blot: To detect Human Resistin by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human Resistin is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P183GBT-1MG will be provided as 2 x 500 μg Adipose tissue is an energy reserve in animals and is strictly regulated
  • Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), perilipin, and resistin
  • Resistin, also known as Adipocyte Secreted Factor (ADSF) and FIZZ3, is a cytokine that is specifically secreted by adipocytes
  • While the function of resistin is not well understood, it appears to have key paracrine roles and has a suggested role in type 2 diabetes
  • Studies show that in obese, diabetic mice the levels of serum resistin are increased, which has an antagonistic effect on insulin
  • Additional studies have shown that resistin causes insulin resistance and glucose intolerance in mice
  • Resistin gene expression requires C/EBP alpha, which is necessary and sufficient for expression
  • Studies show that the coactivators CBP and p300, which have been shown to display histone acetyltransferase (HAT) activity, abundantly acetylate the histones at the resistin promoter suggesting their role in activating chromatin for resistin transcription
  • Numerous PPAR gamma and RXR ligands have been shown to downregulate resistin expression in adipocytes.

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Fischer Scientific

7245498

Goat Polyclonal Antibody...


Antigen:
Resistin

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Goat

Target Species:
Human

Gene Accession No.:
Q9HD89

Gene ID (Entrez):
56729

Immunogen:
E.coli-derived Recombinant Human Resistin

Purification Method:
Antigen affinity chromatography

Gene:
RETN

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
Adipose tissue specific secretory factor; adipose tissue-specific secretory factor; Adipose-specific cysteine-rich secreted protein A12-alpha; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; cysteine-r; Cysteine-rich secreted protein A12-alpha-like 2; cysteine-rich secreted protein FIZZ3; dominant inhibitory adipocyte-specific secretory factor; dri; FIZZ3; found in inflammatory zone 3; HXCP1; MGC126603; MGC126609; Resistin; resistin delta2; RETN; RETN1; RSN; RSTN; UNQ407/PRO1199; XCP1; Xcp4

Gene Symbols:
RETN

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Antigen:
MCP-1

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Rat

Gene Accession No.:
P14844

Gene ID (Entrez):
24770

Immunogen:
E.coli-derived Recombinant Rat MCP-1 (CCL2)

Purification Method:
Antigen affinity chromatography

Gene:
Ccl2

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF

Gene Symbols:
Ccl2

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Rat Monoclonal Antibody...


Antigen:
CD31 (PECAM-1)

Applications:
Flow Cytometry

Conjugate:
Brilliant Violet 711

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
Q08481

Gene ID (Entrez):
18613

Immunogen:
__

Purification Method:
Affinity chromatography

Gene:
Pecam1

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

Gene Symbols:
Pecam1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

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Antigen:
IL-20

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Goat

Target Species:
Human

Gene Accession No.:
Q9NYY1

Gene ID (Entrez):
50604

Immunogen:
E.coli-derived Recombinant Human IL-20

Purification Method:
Antigen affinity chromatography

Gene:
Il20

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
cytokine Zcyto10; four alpha helix cytokine; four alpha helix cytokine ZCYTO10; four helix bundle cytokine 10; il 20; IL10D; Il20; IL-20; ILN; Interleukin; interleukin 20; interleukin-20; MGC96907; PRO1801; UNQ852; UNQ852/PRO1801; ZCYTO10

Gene Symbols:
Il20

Primary or Secondary:
Primary

Content And Storage:
-20°C