7245279

RELM beta Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

RELM beta

Applications

ELISA, Western Blot

Conjugate

Biotin

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q9BQ08

Gene ID (Entrez)

84666

Immunogen

E.coli-derived, 19.0 kDa Recombinant Human RELMbeta

Purification Method

Antigen affinity chromatography

Gene

Retnlb

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

9030012B21Rik; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 2; CCRG; Colon and small intestine-specific cysteine-rich protein; colon carcinoma-related gene protein; cysteine-rich secreted A12-alpha-like protein 1; cysteine-rich secreted protein A12-alpha-like 1; Cysteine-rich secreted protein A12-beta; cysteine-rich secreted protein FIZZ2; FIZZ1; Fizz2; found in inflammatory zone 1; found in inflammatory zone 2; HXCP2; Relmb; RELMbeta; RELM-beta; resistin like beta; resistin-like beta; resistin-like molecule beta; RETNL2; RETNLB; RSNB; UNQ408/PRO770; XCP2; Xcp3

Gene Symbols

Retnlb

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: MQCSLDSVMD KKIKDVLNSL EYSPSPISKK LSCASVKSQG RPSSCPAGMA VTGCACGYGC GSWDVQLETT CHCQCSVVDW TTARCCHLT
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human RELMbeta
  • Anti-Human RELMbeta-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Human RELMbeta by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human RELMbeta (500-P217) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human RELMbeta
  • Western Blot: To detect Human RELMbeta by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Human RELMbeta is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P217BT-1MG will be provided as 2 x 500 μg Adipose tissue is an energy reserve that is strictly regulated in animals
  • Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), perilipin, and resistin
  • Resistin, also known as Adipocyte Secreted Factor (ADSF) and FIZZ3, is a cytokine that is specifically secreted by adipocytes
  • While the function of resistin is not well understood, it appears to have key paracrine roles and has a suggested role in type 2 diabetes
  • Studies show that in obese, diabetic mice the levels of serum resistin are increased, which has an antagonistic effect on insulin
  • Additional studies have shown that resistin causes insulin resistance and glucose intolerance in mice
  • Resistin gene expression requires C/EBP alpha, which is necessary and sufficient for expression
  • Studies show that the coactivators CBP and p300, which have been shown to display histone acetyltransferase (HAT) activity, abundantly acetylate the histones at the resistin promoter suggesting their role in activating chromatin for resistin transcription
  • Numerous PPAR gamma and RXR ligands have been shown to downregulate resistin expression in adipocytes.

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Fischer Scientific

7245279

Rabbit Polyclonal Antibody...


Antigen:
RELM beta

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9BQ08

Gene ID (Entrez):
84666

Immunogen:
E.coli-derived, 19.0 kDa Recombinant Human RELMbeta

Purification Method:
Antigen affinity chromatography

Gene:
Retnlb

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
9030012B21Rik; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 2; CCRG; Colon and small intestine-specific cysteine-rich protein; colon carcinoma-related gene protein; cysteine-rich secreted A12-alpha-like protein 1; cysteine-rich secreted protein A12-alpha-like 1; Cysteine-rich secreted protein A12-beta; cysteine-rich secreted protein FIZZ2; FIZZ1; Fizz2; found in inflammatory zone 1; found in inflammatory zone 2; HXCP2; Relmb; RELMbeta; RELM-beta; resistin like beta; resistin-like beta; resistin-like molecule beta; RETNL2; RETNLB; RSNB; UNQ408/PRO770; XCP2; Xcp3

Gene Symbols:
Retnlb

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Antigen:
MCP-1

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
P10148

Gene ID (Entrez):
20296

Immunogen:
E.coli-derived Recombinant Murine JE/MCP-1 (CCL2)

Purification Method:
Antigen affinity chromatography

Gene:
Ccl2

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF

Gene Symbols:
Ccl2

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Rabbit Polyclonal Antibody...


Antigen:
Epo

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P01588

Gene ID (Entrez):
2056

Immunogen:
CHO cells-derived Recombinant Human EPO

Purification Method:
Antigen affinity chromatography

Gene:
EPO

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2

Gene Symbols:
EPO

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Antigen:
Amphiregulin

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P15514

Gene ID (Entrez):
374

Immunogen:
E.coli-derived Recombinant Human Amphiregulin

Purification Method:
Antigen affinity chromatography

Gene:
AREG

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
amphiregulin; amphiregulin B; AR; AREG; AREGB; colorectum cell-derived growth factor; CRDGF; Mcub; MGC13647; schwannoma-derived growth factor; SDGF

Gene Symbols:
AREG

Primary or Secondary:
Primary

Content And Storage:
-20°C