7245378

Resistin Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Goat Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Resistin

Applications

ELISA, Western Blot

Conjugate

Biotin

Host Species

Goat

Target Species

Mouse

Gene Accession No.

Q99P87

Gene ID (Entrez)

57264

Immunogen

E.coli-derived, 20.2 kDa Recombinant Murine Resistin

Purification Method

Antigen affinity chromatography

Gene

RETN

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

Adipose tissue specific secretory factor; adipose tissue-specific secretory factor; Adipose-specific cysteine-rich secreted protein A12-alpha; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; cysteine-r; Cysteine-rich secreted protein A12-alpha-like 2; cysteine-rich secreted protein FIZZ3; dominant inhibitory adipocyte-specific secretory factor; dri; FIZZ3; found in inflammatory zone 3; HXCP1; MGC126603; MGC126609; Resistin; resistin delta2; RETN; RETN1; RSN; RSTN; UNQ407/PRO1199; XCP1; Xcp4

Gene Symbols

RETN

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: SSMPLCPIDE AIDKKIKQDF NSLFPNAIKN IGLNCWTVSS RGKLASCPEG TAVLSCSCGS ACGSWDIREE KVCHCQCARI DWTAARCCKL QVAS
  • Preparation: Produced from sera of goats immunized with highly pure Recombinant Murine Resistin
  • Anti-Murine Resistin-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect mResistin by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine Resistin (500-P182G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant mResistin
  • Western Blot: To detect Murine Resistin by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine Resistin is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P182GBT-1MG will be provided as 2 x 500 μg Adipose tissue is an energy reserve in animals and is strictly regulated
  • Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), perilipin, and resistin
  • Resistin, also known as Adipocyte Secreted Factor (ADSF) and FIZZ3, is a cytokine that is specifically secreted by adipocytes
  • While the function of resistin is not well understood, it appears to have key paracrine roles and has a suggested role in type 2 diabetes
  • Studies show that in obese, diabetic mice the levels of serum resistin are increased, which has an antagonistic effect on insulin
  • Additional studies have shown that resistin causes insulin resistance and glucose intolerance in mice
  • Resistin gene expression requires C/EBP alpha, which is necessary and sufficient for expression
  • Studies show that the coactivators CBP and p300, which have been shown to display histone acetyltransferase (HAT) activity, abundantly acetylate the histones at the resistin promoter suggesting their role in activating chromatin for resistin transcription
  • Numerous PPAR gamma and RXR ligands have been shown to downregulate resistin expression in adipocytes.

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Fischer Scientific

7245378

Goat Polyclonal Antibody...


Antigen:
Resistin

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Goat

Target Species:
Mouse

Gene Accession No.:
Q99P87

Gene ID (Entrez):
57264

Immunogen:
E.coli-derived, 20.2 kDa Recombinant Murine Resistin

Purification Method:
Antigen affinity chromatography

Gene:
RETN

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
Adipose tissue specific secretory factor; adipose tissue-specific secretory factor; Adipose-specific cysteine-rich secreted protein A12-alpha; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; cysteine-r; Cysteine-rich secreted protein A12-alpha-like 2; cysteine-rich secreted protein FIZZ3; dominant inhibitory adipocyte-specific secretory factor; dri; FIZZ3; found in inflammatory zone 3; HXCP1; MGC126603; MGC126609; Resistin; resistin delta2; RETN; RETN1; RSN; RSTN; UNQ407/PRO1199; XCP1; Xcp4

Gene Symbols:
RETN

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Fischer Scientific

7245379

Goat Polyclonal Antibody...


Antigen:
PPBP

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Goat

Target Species:
Human

Gene Accession No.:
P02775

Gene ID (Entrez):
5473

Immunogen:
E.coli-derived, 7.6 kDa Recombinant Human NAP-2 (CXCL7)

Purification Method:
Antigen affinity chromatography

Gene:
PPBP

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
2400003M24Rik; AI854500; Beta-TG; Beta-thromboglobulin; b-TG1; chemokine (C-X-C motif) ligand 7; connective tissue-activating peptide III; Connective tissue-activating peptide III(1-81); CTAP3; CTAPIII; CTAP-III; CTAP-III(1-81); CXC chemokine ligand 7; C-X-C motif chemokine 7; CXCL7; LA-PF4; LDGF; Leukocyte-derived growth factor; low-affinity platelet factor IV; Macrophage-derived growth factor; MDGF; NAP-2; NAP-2(1-63); NAP-2(1-66); NAP-2(73); NAP-2(74); NAP-2-L1; neutrophil activating peptide-2; neutrophil-activating peptide 2; Neutrophil-activating peptide 2(1-63); Neutrophil-activating peptide 2(1-66); Neutrophil-activating peptide 2(73); Neutrophil-activating peptide 2(74); neutrophil-activating peptide-2; PBP; Platelet basic protein; PPBP; pro-platelet basic protein; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7); SCYB7; small inducible cytokine B7; small inducible cytokine subfamily B, member 7; small-inducible cytokine B7; TC1; TC-1; TC2; TC-2; TGB; TGB1; THBGB;

Gene Symbols:
PPBP

Primary or Secondary:
Primary

Content And Storage:
-20°C

Img

Fischer Scientific

7245379

Goat Polyclonal Antibody...


Antigen:
PPBP

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Goat

Target Species:
Human

Gene Accession No.:
P02775

Gene ID (Entrez):
5473

Immunogen:
E.coli-derived, 7.6 kDa Recombinant Human NAP-2 (CXCL7)

Purification Method:
Antigen affinity chromatography

Gene:
PPBP

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
2400003M24Rik; AI854500; Beta-TG; Beta-thromboglobulin; b-TG1; chemokine (C-X-C motif) ligand 7; connective tissue-activating peptide III; Connective tissue-activating peptide III(1-81); CTAP3; CTAPIII; CTAP-III; CTAP-III(1-81); CXC chemokine ligand 7; C-X-C motif chemokine 7; CXCL7; LA-PF4; LDGF; Leukocyte-derived growth factor; low-affinity platelet factor IV; Macrophage-derived growth factor; MDGF; NAP-2; NAP-2(1-63); NAP-2(1-66); NAP-2(73); NAP-2(74); NAP-2-L1; neutrophil activating peptide-2; neutrophil-activating peptide 2; Neutrophil-activating peptide 2(1-63); Neutrophil-activating peptide 2(1-66); Neutrophil-activating peptide 2(73); Neutrophil-activating peptide 2(74); neutrophil-activating peptide-2; PBP; Platelet basic protein; PPBP; pro-platelet basic protein; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7); SCYB7; small inducible cytokine B7; small inducible cytokine subfamily B, member 7; small-inducible cytokine B7; TC1; TC-1; TC2; TC-2; TGB; TGB1; THBGB;

Gene Symbols:
PPBP

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7245380

Rabbit Polyclonal Antibody...


Antigen:
IL-10

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
P18893

Gene ID (Entrez):
16153

Immunogen:
E.coli-derived Recombinant Murine IL-10

Purification Method:
Antigen affinity chromatography

Gene:
IL10

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

Gene Symbols:
IL10

Primary or Secondary:
Primary

Content And Storage:
-20°C