7245379

PPBP Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Goat Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

PPBP

Applications

ELISA, Western Blot

Conjugate

Biotin

Host Species

Goat

Target Species

Human

Gene Accession No.

P02775

Gene ID (Entrez)

5473

Immunogen

E.coli-derived, 7.6 kDa Recombinant Human NAP-2 (CXCL7)

Purification Method

Antigen affinity chromatography

Gene

PPBP

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

2400003M24Rik; AI854500; Beta-TG; Beta-thromboglobulin; b-TG1; chemokine (C-X-C motif) ligand 7; connective tissue-activating peptide III; Connective tissue-activating peptide III(1-81); CTAP3; CTAPIII; CTAP-III; CTAP-III(1-81); CXC chemokine ligand 7; C-X-C motif chemokine 7; CXCL7; LA-PF4; LDGF; Leukocyte-derived growth factor; low-affinity platelet factor IV; Macrophage-derived growth factor; MDGF; NAP-2; NAP-2(1-63); NAP-2(1-66); NAP-2(73); NAP-2(74); NAP-2-L1; neutrophil activating peptide-2; neutrophil-activating peptide 2; Neutrophil-activating peptide 2(1-63); Neutrophil-activating peptide 2(1-66); Neutrophil-activating peptide 2(73); Neutrophil-activating peptide 2(74); neutrophil-activating peptide-2; PBP; Platelet basic protein; PPBP; pro-platelet basic protein; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7); SCYB7; small inducible cytokine B7; small inducible cytokine subfamily B, member 7; small-inducible cytokine B7; TC1; TC-1; TC2; TC-2; TGB; TGB1; THBGB;

Gene Symbols

PPBP

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KDGRKICLDP DAPRIKKIVQ KKLAGDESAD
  • Preparation: Produced from sera of goats immunized with highly pure Recombinant Human NAP-2 (CXCL7)
  • Anti-Human NAP-2 (CXCL7)-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Human NAP-2 by sandwich ELISA (using 100 μL/well) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human NAP-2 (CXCL7) (500-P03) as a capture antibody, allows the detection of at least 2000-4000 pg/mL of Recombinant Human NAP-2
  • Western Blot: To detect Human NAP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • When used in conjunction with compatible development reagents the detection limit for Recombinant Human NAP-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P03GBT-1MG will be provided as 2 x 500 μg Members of the a-chemokine subfamily of inducible, secreted, pro-inflammatory cytokines contain a similar motif, in which the first two cysteine residues are separated by a single residue (Cys-X-Cys), and are also chemotactic for neutrophils
  • The platelet basic protein (PBP), a member of the a-chemokine family, resides in the a-granules of platelets and is released upon their activation
  • Proteolytic cleavage of the amino terminus of PBP leads to the generation of several peptides, which include mature PBP, connective tissue-activating peptide III (CTAP III, also designated low affinity platelet factor IV (LA-PF4)), b-thromboglobulin (b-TG), and neutrophil-activating peptide 2 (NAP-2)
  • PBP and its N-truncated derivatives mediate inflammation and wound healing
  • Specifically, NAP-2 activates chemotaxis and degranulation in neutrophils during inflammation
  • The gene encoding human PBP maps to chromosome 4q12-q13.

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Fischer Scientific

7245379

Goat Polyclonal Antibody...


Antigen:
PPBP

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Goat

Target Species:
Human

Gene Accession No.:
P02775

Gene ID (Entrez):
5473

Immunogen:
E.coli-derived, 7.6 kDa Recombinant Human NAP-2 (CXCL7)

Purification Method:
Antigen affinity chromatography

Gene:
PPBP

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
2400003M24Rik; AI854500; Beta-TG; Beta-thromboglobulin; b-TG1; chemokine (C-X-C motif) ligand 7; connective tissue-activating peptide III; Connective tissue-activating peptide III(1-81); CTAP3; CTAPIII; CTAP-III; CTAP-III(1-81); CXC chemokine ligand 7; C-X-C motif chemokine 7; CXCL7; LA-PF4; LDGF; Leukocyte-derived growth factor; low-affinity platelet factor IV; Macrophage-derived growth factor; MDGF; NAP-2; NAP-2(1-63); NAP-2(1-66); NAP-2(73); NAP-2(74); NAP-2-L1; neutrophil activating peptide-2; neutrophil-activating peptide 2; Neutrophil-activating peptide 2(1-63); Neutrophil-activating peptide 2(1-66); Neutrophil-activating peptide 2(73); Neutrophil-activating peptide 2(74); neutrophil-activating peptide-2; PBP; Platelet basic protein; PPBP; pro-platelet basic protein; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7); SCYB7; small inducible cytokine B7; small inducible cytokine subfamily B, member 7; small-inducible cytokine B7; TC1; TC-1; TC2; TC-2; TGB; TGB1; THBGB;

Gene Symbols:
PPBP

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Antigen:
IL-10

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
P18893

Gene ID (Entrez):
16153

Immunogen:
E.coli-derived Recombinant Murine IL-10

Purification Method:
Antigen affinity chromatography

Gene:
IL10

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF

Gene Symbols:
IL10

Primary or Secondary:
Primary

Content And Storage:
-20°C

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Mouse Monoclonal Antibody...


Antigen:
SERPINA3

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01011

Gene ID (Entrez):
12

Immunogen:
Purified human serum alpha-1 Antichymotrypsin.

Purification Method:
Protein A

Gene:
SERPINA3

Concentration:
1.9 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative; pH 7.4

Gene Alias:
AACT; ACT; alpha-1-antichymotrypsin; Alpha-1-antichymotrypsin His-Pro-less; Cell growth-inhibiting gene 24/25 protein; GIG24; GIG25; Growth inhibiting protein 24; Growth inhibiting protein 25; growth-inhibiting protein 24; growth-inhibiting protein 25; MGC88254; Serine (or cysteine) proteinase inhibitor clade A member 3; serine (or cysteine) proteinase inhibitor, clade A, member 3; serpin A3; serpin family A member 3; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; SERPINA3

Gene Symbols:
SERPINA3

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

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7245381

Mouse Monoclonal Antibody...


Antigen:
SERPINA3

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01011

Gene ID (Entrez):
12

Immunogen:
Purified human serum alpha-1 Antichymotrypsin.

Purification Method:
Protein A

Gene:
SERPINA3

Concentration:
1.9 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with no preservative; pH 7.4

Gene Alias:
AACT; ACT; alpha-1-antichymotrypsin; Alpha-1-antichymotrypsin His-Pro-less; Cell growth-inhibiting gene 24/25 protein; GIG24; GIG25; Growth inhibiting protein 24; Growth inhibiting protein 25; growth-inhibiting protein 24; growth-inhibiting protein 25; MGC88254; Serine (or cysteine) proteinase inhibitor clade A member 3; serine (or cysteine) proteinase inhibitor, clade A, member 3; serpin A3; serpin family A member 3; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; SERPINA3

Gene Symbols:
SERPINA3

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles