7245278

CCL4 Polyclonal Antibody, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CCL4

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P13236

Gene ID (Entrez)

6351

Immunogen

E.coli-derived Recombinant Human MIP-1beta (CCL4)

Purification Method

Antigen affinity chromatography

Gene

CCL4

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

ACT2; ACT-2; AT744.1; CC chemokine ligand 4; C-C motif chemokine 4; C-C motif chemokine ligand 4; Ccl4; chemokine (C-C motif) ligand 4; G-26; G-26 T-lymphocyte-secreted protein; HC21; immune activation gene 2; immune activation gene-2; immune activation protein 2; LAG1; LAG-1; Lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; macrophage inflammatory protein-1 beta; MGC104418; MGC126025; MGC126026; MIP-1 beta; MIP1b; MIP-1B; Mip1-b; MIP1B1; MIP1beta; MIP-1BETA; MIP-1-beta; MIP1-beta; MIP-1-beta(1-69); MIP-1-beta(3-69); PAT 744; Protein H400; putative MIP-1beta protein; RP23-320E6.8; SCY4A; SCYA2; Scya4; secreted protein G-26; SIS-gamma; small inducible cytokine A4; small inducible cytokine A4 (homologous to mouse Mip-1b); small-inducible cytokine A4; T-cell activation protein 2

Gene Symbols

CCL4

Primary or Secondary

Primary

Content And Storage

-20°C

Related Products

Img

Fischer Scientific

7245569

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7245325

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7245450

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7245016

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7244982

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7245249

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7245676

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7245499

Rabbit Polyclonal Antibody...

Description

  • AA Sequence of recombinant protein: APMGSDPPTA CCFSYTARKL PHNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human MIP-1beta (CCL4)
  • Anti-Human MIP-1beta (CCL4)-specific antibody was purified by affinity chromatography employing an immobilized Human MIP-1beta (CCL4) matrix
  • Sandwich ELISA: To detect Human MIP-1beta (CCL4) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
  • This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human MIP-1beta (CCL4) (500-P38BBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human MIP-1beta (CCL4)
  • Western Blot: To detect Human MIP-1beta by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Human MIP-1beta is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • CCL4 (macrophage inflammatory protein 1-beta, MIP1B) belongs to the intercrine beta (chemokine CC) family
  • Functionally, CCL4 is involved in chemotactic and proinflammatory effects, and homeostasis
  • CCL4 is produced by macrophages upon stimulation by bacterial endotoxins
  • CCL4 recruits and stimulates various inflammatory cells at sites of inflammation
  • CCL4 is produced by lymphocytes, macrophages and dendritic cells
  • Both CCL4 and the related protein CCL3 participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells
  • While both CCL4 and CCL3 exert similar effects on monocytes, their effect on lymphocytes differ, with CCL4 selectively attracting CD4+ lymphocytes and CCL3 selectively attracting CD8+ lymphocytes
  • Additionally, both have been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells
  • The processed form of CCL4 can induce down-modulation of surface expression of the chemokine receptor CCR5, thus inhibiting the CCR5-mediated entry of HIV-1 in T cells
  • CCL4 binds with high affinity to CCR5 receptors.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7245278

Rabbit Polyclonal Antibody...


Antigen:
CCL4

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P13236

Gene ID (Entrez):
6351

Immunogen:
E.coli-derived Recombinant Human MIP-1beta (CCL4)

Purification Method:
Antigen affinity chromatography

Gene:
CCL4

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
ACT2; ACT-2; AT744.1; CC chemokine ligand 4; C-C motif chemokine 4; C-C motif chemokine ligand 4; Ccl4; chemokine (C-C motif) ligand 4; G-26; G-26 T-lymphocyte-secreted protein; HC21; immune activation gene 2; immune activation gene-2; immune activation protein 2; LAG1; LAG-1; Lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; macrophage inflammatory protein-1 beta; MGC104418; MGC126025; MGC126026; MIP-1 beta; MIP1b; MIP-1B; Mip1-b; MIP1B1; MIP1beta; MIP-1BETA; MIP-1-beta; MIP1-beta; MIP-1-beta(1-69); MIP-1-beta(3-69); PAT 744; Protein H400; putative MIP-1beta protein; RP23-320E6.8; SCY4A; SCYA2; Scya4; secreted protein G-26; SIS-gamma; small inducible cytokine A4; small inducible cytokine A4 (homologous to mouse Mip-1b); small-inducible cytokine A4; T-cell activation protein 2

Gene Symbols:
CCL4

Primary or Secondary:
Primary

Content And Storage:
-20°C

Img

Fischer Scientific

7245279

Rabbit Polyclonal Antibody...


Antigen:
RELM beta

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9BQ08

Gene ID (Entrez):
84666

Immunogen:
E.coli-derived, 19.0 kDa Recombinant Human RELMbeta

Purification Method:
Antigen affinity chromatography

Gene:
Retnlb

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
9030012B21Rik; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 2; CCRG; Colon and small intestine-specific cysteine-rich protein; colon carcinoma-related gene protein; cysteine-rich secreted A12-alpha-like protein 1; cysteine-rich secreted protein A12-alpha-like 1; Cysteine-rich secreted protein A12-beta; cysteine-rich secreted protein FIZZ2; FIZZ1; Fizz2; found in inflammatory zone 1; found in inflammatory zone 2; HXCP2; Relmb; RELMbeta; RELM-beta; resistin like beta; resistin-like beta; resistin-like molecule beta; RETNL2; RETNLB; RSNB; UNQ408/PRO770; XCP2; Xcp3

Gene Symbols:
Retnlb

Primary or Secondary:
Primary

Content And Storage:
-20°C

Img

Fischer Scientific

7245282

Rabbit Polyclonal Antibody...


Antigen:
MCP-1

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
P10148

Gene ID (Entrez):
20296

Immunogen:
E.coli-derived Recombinant Murine JE/MCP-1 (CCL2)

Purification Method:
Antigen affinity chromatography

Gene:
Ccl2

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF

Gene Symbols:
Ccl2

Primary or Secondary:
Primary

Content And Storage:
-20°C

Img

Fischer Scientific

7245283

Rabbit Polyclonal Antibody...


Antigen:
Epo

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P01588

Gene ID (Entrez):
2056

Immunogen:
CHO cells-derived Recombinant Human EPO

Purification Method:
Antigen affinity chromatography

Gene:
EPO

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2

Gene Symbols:
EPO

Primary or Secondary:
Primary

Content And Storage:
-20°C