7245333
TNF alpha Polyclonal Antibody, PeproTech®, Invitrogen™
Goat Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
TNF alpha
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Host Species
Goat
Target Species
Mouse
Gene Accession No.
P06804
Gene ID (Entrez)
21926
Immunogen
E.coli-derived Recombinant Murine TNF-alpha
Purification Method
Antigen affinity chromatography
Gene
Tnf
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Gene Symbols
Tnf
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL
- Preparation: Produced from sera of goats immunized with highly pure Recombinant Murine TNF-alpha
- Anti-Murine TNF-alpha-specific antibody was purified by affinity chromatography employing an immobilized Murine TNF-alpha matrix
- Sandwich ELISA: To detect Murine TNF-alpha by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
- This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Murine TNF-alpha (500-P64GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine TNF-alpha
- Western Blot: To detect Murine TNF-alpha by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Murine TNF-alpha is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily
- This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR
- TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation
- TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions
- Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice
- Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors
- TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity
- This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
Compare Similar Items
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Antigen: TNF alpha
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Mouse
Gene Accession No.: P06804
Gene ID (Entrez): 21926
Immunogen: E.coli-derived Recombinant Murine TNF-alpha
Purification Method: Antigen affinity chromatography
Gene: Tnf
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Gene Symbols: Tnf
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
TNF alpha
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Mouse
Gene Accession No.:
P06804
Gene ID (Entrez):
21926
Immunogen:
E.coli-derived Recombinant Murine TNF-alpha
Purification Method:
Antigen affinity chromatography
Gene:
Tnf
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Gene Symbols:
Tnf
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Leptin
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P41159
Gene ID (Entrez): 3952
Immunogen: E.coli-derived Recombinant Human Leptin
Purification Method: Antigen affinity chromatography
Gene: Lep
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Gene Symbols: Lep
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
Leptin
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P41159
Gene ID (Entrez):
3952
Immunogen:
E.coli-derived Recombinant Human Leptin
Purification Method:
Antigen affinity chromatography
Gene:
Lep
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Gene Symbols:
Lep
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: CXCL6
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: E.coli-derived Recombinant Murine LIX (CXCL6) (92 a.a.)
Purification Method: Antigen affinity chromatography
Gene: __
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 5; chemokine (C-X-C motif) ligand 6; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); chemokine alpha 3; CKA3; CKA-3; CXC; CXC chemokine LIX; CXC motif chemokine; C-X-C motif chemokine 5; C-X-C motif chemokine 6; C-X-C motif chemokine ligand 6; CXCL; Cxcl5; CXCL6; Cytokine LIX; GCP2; GCP-2; granulocyte chemotactic protein 2; Scyb5; SCYB6; small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2); Small inducible cytokine subfamily B (Cys-X-Cys), member b; small-inducible cytokine B5; Small-inducible cytokine B6; Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3
Gene Symbols: __
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
CXCL6
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
E.coli-derived Recombinant Murine LIX (CXCL6) (92 a.a.)
Purification Method:
Antigen affinity chromatography
Gene:
__
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 5; chemokine (C-X-C motif) ligand 6; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); chemokine alpha 3; CKA3; CKA-3; CXC; CXC chemokine LIX; CXC motif chemokine; C-X-C motif chemokine 5; C-X-C motif chemokine 6; C-X-C motif chemokine ligand 6; CXCL; Cxcl5; CXCL6; Cytokine LIX; GCP2; GCP-2; granulocyte chemotactic protein 2; Scyb5; SCYB6; small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2); Small inducible cytokine subfamily B (Cys-X-Cys), member b; small-inducible cytokine B5; Small-inducible cytokine B6; Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3
Gene Symbols:
__
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: Neutrophil elastase
Applications: ELISA
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P08246
Gene ID (Entrez): 1991
Immunogen: Purified human Neutrophil Elastase.
Purification Method: Protein A
Gene: ELANE
Concentration: 0.91 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.4
Gene Alias: bone marrow serine protease; ELA2; ELA2A; ELANE; Elastase; elastase 2, neutrophil; elastase, neutrophil expressed; Elastase2; elastase-2; F430011M15Rik; GE; granulocyte-derived elastase; HLE; HNE; Human leukocyte elastase; Leukocyte elastase; medullasin; NE; neutrophil elastase; PE-1; PMN elastase; PMN-E; polymorphonuclear elastase; SCN1; serine protease
Gene Symbols: ELANE
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Antigen:
Neutrophil elastase
Applications:
ELISA
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P08246
Gene ID (Entrez):
1991
Immunogen:
Purified human Neutrophil Elastase.
Purification Method:
Protein A
Gene:
ELANE
Concentration:
0.91 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.4
Gene Alias:
bone marrow serine protease; ELA2; ELA2A; ELANE; Elastase; elastase 2, neutrophil; elastase, neutrophil expressed; Elastase2; elastase-2; F430011M15Rik; GE; granulocyte-derived elastase; HLE; HNE; Human leukocyte elastase; Leukocyte elastase; medullasin; NE; neutrophil elastase; PE-1; PMN elastase; PMN-E; polymorphonuclear elastase; SCN1; serine protease
Gene Symbols:
ELANE
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles