7245433
RANKL (soluble) Polyclonal Antibody, PeproTech®, Invitrogen™
Goat Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
RANKL (soluble)
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Host Species
Goat
Target Species
Human
Gene Accession No.
O14788
Gene ID (Entrez)
8600
Immunogen
E.coli-derived Recombinant Human sRANK Ligand
Purification Method
Antigen affinity chromatography
Gene
TNFSF11
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Gene Symbols
TNFSF11
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: MEKAMVDGSW LDLAKRSKLE AQPFAHLTIN ATDIPSGSHK VSLSSWYHDR GWAKISNMTF SNGKLIVNQD GFYYLYANIC FRHHETSGDL ATEYLQLMVY VTKTSIKIPS SHTLMKGGST KYWSGNSEFH FYSINVGGFF KLRSGEEISI EVSNPSLLDP DQDATYFGAF KVRDID
- Preparation: Produced from sera of goats immunized with highly pure Recombinant Human sRANK Ligand
- Anti-Human sRANK Ligand-specific antibody was purified by affinity chromatography employing an immobilized Human sRANK Ligand matrix
- Sandwich ELISA: To detect Human sRANK Ligand by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
- This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human sRANK Ligand (500-P133GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human sRANK Ligand
- Western Blot: To detect Human sRANK Ligand by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human sRANK Ligand is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation
- This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response
- T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss
- This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis
- Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts
- The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy
- Two alternatively spliced transcript variants have been found.
Compare Similar Items
Show Difference
Antigen: RANKL (soluble)
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Human
Gene Accession No.: O14788
Gene ID (Entrez): 8600
Immunogen: E.coli-derived Recombinant Human sRANK Ligand
Purification Method: Antigen affinity chromatography
Gene: TNFSF11
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Gene Symbols: TNFSF11
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
RANKL (soluble)
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
O14788
Gene ID (Entrez):
8600
Immunogen:
E.coli-derived Recombinant Human sRANK Ligand
Purification Method:
Antigen affinity chromatography
Gene:
TNFSF11
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Gene Symbols:
TNFSF11
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: MCP-2
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P80075
Gene ID (Entrez): 6355
Immunogen: E.coli-derived Recombinant Human MCP-2 (CCL8)
Purification Method: Antigen affinity chromatography
Gene: CCL8
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: 1810063B20Rik; AB023418; C-C motif chemokine 8; C-C motif chemokine ligand 8; CCL8; chemokine (C-C motif) ligand 8; HC14; MCP2; MCP-2; MCP-2(6-76); monocyte chemoattractant protein 2; monocyte chemoattractant protein-2; monocyte chemotactic protein 2; SCYA10; SCYA8; small inducible cytokine A8; small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2); small-inducible cytokine A8
Gene Symbols: CCL8
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
MCP-2
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P80075
Gene ID (Entrez):
6355
Immunogen:
E.coli-derived Recombinant Human MCP-2 (CCL8)
Purification Method:
Antigen affinity chromatography
Gene:
CCL8
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
1810063B20Rik; AB023418; C-C motif chemokine 8; C-C motif chemokine ligand 8; CCL8; chemokine (C-C motif) ligand 8; HC14; MCP2; MCP-2; MCP-2(6-76); monocyte chemoattractant protein 2; monocyte chemoattractant protein-2; monocyte chemotactic protein 2; SCYA10; SCYA8; small inducible cytokine A8; small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2); small-inducible cytokine A8
Gene Symbols:
CCL8
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: MCP-2
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P80075
Gene ID (Entrez): 6355
Immunogen: E.coli-derived Recombinant Human MCP-2 (CCL8)
Purification Method: Antigen affinity chromatography
Gene: CCL8
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: 1810063B20Rik; AB023418; C-C motif chemokine 8; C-C motif chemokine ligand 8; CCL8; chemokine (C-C motif) ligand 8; HC14; MCP2; MCP-2; MCP-2(6-76); monocyte chemoattractant protein 2; monocyte chemoattractant protein-2; monocyte chemotactic protein 2; SCYA10; SCYA8; small inducible cytokine A8; small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2); small-inducible cytokine A8
Gene Symbols: CCL8
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
MCP-2
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P80075
Gene ID (Entrez):
6355
Immunogen:
E.coli-derived Recombinant Human MCP-2 (CCL8)
Purification Method:
Antigen affinity chromatography
Gene:
CCL8
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
1810063B20Rik; AB023418; C-C motif chemokine 8; C-C motif chemokine ligand 8; CCL8; chemokine (C-C motif) ligand 8; HC14; MCP2; MCP-2; MCP-2(6-76); monocyte chemoattractant protein 2; monocyte chemoattractant protein-2; monocyte chemotactic protein 2; SCYA10; SCYA8; small inducible cytokine A8; small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2); small-inducible cytokine A8
Gene Symbols:
CCL8
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: beta-3 Defensin
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P81534
Gene ID (Entrez): 414325
Immunogen: E.coli-derived Recombinant Human BD-3
Purification Method: Antigen affinity chromatography
Gene: DEFB103A
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: BD3; BD-3; beta defensin 3; beta defensin-3; beta-defensin 103; Beta-defensin 3; DEFB103; DEFB103A; DEFB103B; DEFB3; DEFB-3; defensin beta 103A; defensin, beta 103; defensin, beta 103A; defensin, beta 3; defensin-like protein; HBD3; hBD-3; HBP3; HBP-3
Gene Symbols: DEFB103A
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
beta-3 Defensin
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P81534
Gene ID (Entrez):
414325
Immunogen:
E.coli-derived Recombinant Human BD-3
Purification Method:
Antigen affinity chromatography
Gene:
DEFB103A
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
BD3; BD-3; beta defensin 3; beta defensin-3; beta-defensin 103; Beta-defensin 3; DEFB103; DEFB103A; DEFB103B; DEFB3; DEFB-3; defensin beta 103A; defensin, beta 103; defensin, beta 103A; defensin, beta 3; defensin-like protein; HBD3; hBD-3; HBP3; HBP-3
Gene Symbols:
DEFB103A
Primary or Secondary:
Primary
Content And Storage:
-20°C