7245661
TRAIL (soluble) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
TRAIL (soluble)
Applications
ELISA, Western Blot
Conjugate
Biotin
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P50591
Gene ID (Entrez)
8743
Immunogen
E.coli-derived, 19.6 kDa Recombinant Human sTRAIL/Apo2L
Purification Method
Antigen affinity chromatography
Gene
TNFSF10
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10
Gene Symbols
TNFSF10
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: MRERGPQRVA AHITGTRGRS NTLSSPNSKN EKALGRKINS WESSRSGHSF LSNLHLRNGE LVIHEKGFYY IYSQTYFRFQ EEIKENTKND KQMVQYIYKY TSYPDPILLM KSARNSCWSK DAEYGLYSIY QGGIFELKEN DRIFVSVTNE HLIDMDHEAS FFGAFLVG
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human sTRAIL/Apo2L
- Anti-Human sTRAIL/Apo2L-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect Human sTRAIL/Apo2L by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human sTRAIL/Apo2L (500-P135) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human sTRAIL/Apo2L
- Western Blot: To detect Human sTRAIL/Apo2L by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human sTRAIL/Apo2L is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P135BT-1MG will be provided as 2 x 500 μg TRAIL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family
- TRAIL preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues
- TRAIL binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG
- The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis
- The binding of TRAIL protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3
- Receptors for TRAIL include two death domain containing receptors, death receptor 4 (DR4) and DR5, as well as two decoy receptors, DcR1 and DcR2, lacking the intracellular signaling death domain
- TRAIL is a type II membrane protein and expressed in a variety of human tissues
- Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells.
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Antigen: TRAIL (soluble)
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P50591
Gene ID (Entrez): 8743
Immunogen: E.coli-derived, 19.6 kDa Recombinant Human sTRAIL/Apo2L
Purification Method: Antigen affinity chromatography
Gene: TNFSF10
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10
Gene Symbols: TNFSF10
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
TRAIL (soluble)
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P50591
Gene ID (Entrez):
8743
Immunogen:
E.coli-derived, 19.6 kDa Recombinant Human sTRAIL/Apo2L
Purification Method:
Antigen affinity chromatography
Gene:
TNFSF10
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10
Gene Symbols:
TNFSF10
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: VEGF-165
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Rat
Gene Accession No.: P16612
Gene ID (Entrez): 83785
Immunogen: E.coli-derived Recombinant Rat VEGF 165
Purification Method: Antigen affinity chromatography
Gene: Vegfa
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: __
Gene Symbols: Vegfa
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
VEGF-165
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Rat
Gene Accession No.:
P16612
Gene ID (Entrez):
83785
Immunogen:
E.coli-derived Recombinant Rat VEGF 165
Purification Method:
Antigen affinity chromatography
Gene:
Vegfa
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
__
Gene Symbols:
Vegfa
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: beta-Defensin 1
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P60022
Gene ID (Entrez): 1672
Immunogen: E.coli-derived Recombinant Human BD-1 (47 a.a.)
Purification Method: Antigen affinity chromatography
Gene: DEFB1
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: AW260221; BD1; BD-1; beta defensin 1; beta-defensin 1; beta-defensin-1; DEFB1; DEFB-1; DEFB101; defensin beta 1; defensin, beta 1; HBD1; rBD-1
Gene Symbols: DEFB1
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
beta-Defensin 1
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P60022
Gene ID (Entrez):
1672
Immunogen:
E.coli-derived Recombinant Human BD-1 (47 a.a.)
Purification Method:
Antigen affinity chromatography
Gene:
DEFB1
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
AW260221; BD1; BD-1; beta defensin 1; beta-defensin 1; beta-defensin-1; DEFB1; DEFB-1; DEFB101; defensin beta 1; defensin, beta 1; HBD1; rBD-1
Gene Symbols:
DEFB1
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: LIGHT
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: Q9QYH9
Gene ID (Entrez): 50930
Immunogen: E.coli-derived Recombinant Murine LIGHT
Purification Method: Antigen affinity chromatography
Gene: TNFSF14
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: CD258; Herpes virus entry mediator ligand; herpesvirus entry mediator ligand; HVEML; HVEM-L; Light; LTg; Ly113; sCD258; sLIGHT; soluble CD258; soluble LIGHT; Tnfsf14; TR2; tumor necrosis factor (ligand) superfamily, member 14; tumor necrosis factor ligand 1D; tumor necrosis factor ligand superfamily member 14; Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form; tumor necrosis factor superfamily member 14; UNQ391/PRO726
Gene Symbols: TNFSF14
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
LIGHT
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
Q9QYH9
Gene ID (Entrez):
50930
Immunogen:
E.coli-derived Recombinant Murine LIGHT
Purification Method:
Antigen affinity chromatography
Gene:
TNFSF14
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
CD258; Herpes virus entry mediator ligand; herpesvirus entry mediator ligand; HVEML; HVEM-L; Light; LTg; Ly113; sCD258; sLIGHT; soluble CD258; soluble LIGHT; Tnfsf14; TR2; tumor necrosis factor (ligand) superfamily, member 14; tumor necrosis factor ligand 1D; tumor necrosis factor ligand superfamily member 14; Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form; tumor necrosis factor superfamily member 14; UNQ391/PRO726
Gene Symbols:
TNFSF14
Primary or Secondary:
Primary
Content And Storage:
-20°C