7245544

EGF Polyclonal Antibody, PeproTech®, Invitrogen™

Goat Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

EGF

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Host Species

Goat

Target Species

Mouse

Gene Accession No.

P01132

Gene ID (Entrez)

13645

Immunogen

E.coli-derived Recombinant Murine EGF

Purification Method

Antigen affinity chromatography

Gene

EGF

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

AI790464; beta-urogastrone; EGF; Epidermal growth factor; epidermal growth factor (beta-urogastrone); epidermal growth factor precursor; H-EGF; HOMG4; Pro-epidermal growth factor; Pro-epidermal growth factor precursor (EGF); sb:eu639; URG; Urogastrone

Gene Symbols

EGF

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR
  • Preparation: Produced from sera of goats immunized with highly pure Recombinant Murine EGF
  • Anti-Murine EGF-specific antibody was purified by affinity chromatography employing an immobilized Murine EGF matrix
  • Sandwich ELISA: To detect Murine EGF by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required
  • This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Murine EGF (500-P174GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine EGF
  • Western Blot: To detect Murine EGF by Western Blot analysis this antibody can be used at a concentration of 0.1- 0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine EGF is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • EGF (Epidermal growth factor) exerts its actions by binding to the EGF Receptor, a 170 kDa protein kinase
  • Activation of EGFR initiates diverse cellular pathways in response to toxic environmental stimuli, or to EGF binding to the receptor, the EGFR forms homo- or heterodimers with other family members
  • Each dimeric receptor complex initiates a distinct signaling pathway by recruiting different Src homology 2 (SH2) containing effector proteins
  • EGF is far and wide expressed in kidney, cerebrum, prostrate and salivary glands
  • EGF acts as a potent mitogenic factor and the phosphorylated receptor recruits adapter proteins like GRB2 that activates complex downstream signaling cascades
  • EGF activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STAT modules
  • Research studies suggest the protein may also play important role in activating the NF-kappa-B signaling cascade
  • Defects in the EGGF gene are the cause of hypomagnesemia type 4 and dysregulation has been associated with the growth and progression of certain cancers.

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Fischer Scientific

7245544

Goat Polyclonal Antibody...


Antigen:
EGF

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Goat

Target Species:
Mouse

Gene Accession No.:
P01132

Gene ID (Entrez):
13645

Immunogen:
E.coli-derived Recombinant Murine EGF

Purification Method:
Antigen affinity chromatography

Gene:
EGF

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
AI790464; beta-urogastrone; EGF; Epidermal growth factor; epidermal growth factor (beta-urogastrone); epidermal growth factor precursor; H-EGF; HOMG4; Pro-epidermal growth factor; Pro-epidermal growth factor precursor (EGF); sb:eu639; URG; Urogastrone

Gene Symbols:
EGF

Primary or Secondary:
Primary

Content And Storage:
-20°C

Img

Fischer Scientific

7245546

Rabbit Polyclonal Antibody...


Antigen:
FLT3LG

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P49771

Gene ID (Entrez):
2323

Immunogen:
E.coli-derived Recombinant Human Flt3-Ligand

Purification Method:
Antigen affinity chromatography

Gene:
FLT3LG

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
FL; Flt 3 ligand; Flt3; Flt3 L; Flt3 ligand; Flt3l; Flt3lg; fms related receptor tyrosine kinase 3 ligand; fms related tyrosine kinase 3 ligand; FMS-like tyrosine kinase 3 ligand; fms-related tyrosine kinase 3; fms-related tyrosine kinase 3 ligand; H-FLT-3-L; Ly72L; M-FLT-3-L; NEWGENE_2322792; SL cytokine

Gene Symbols:
FLT3LG

Primary or Secondary:
Primary

Content And Storage:
-20°C

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7245548

Rabbit Polyclonal Antibody...


Antigen:
IL-1 alpha

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P01583

Gene ID (Entrez):
3552

Immunogen:
E.coli-derived Recombinant Human IL-1alpha

Purification Method:
Antigen affinity chromatography

Gene:
Il1a

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
CTLA8; hematopoietin-1; IL 1 a; IL 1a; IL1; IL-1 alpha; IL17; IL1A; Il-1a; IL-1alpha; IL1-ALPHA; IL1F1; IL1a; ILN; Interleukin; interleukin 1 alpha; interleukin 1, alpha; interleukin 17; interleukin 1a; interleukin 1-alpha; interleukin 1-alpha (AA 1 - 152); Interleukin1 alpha; interleukin-1 alpha; interleukin-1 alpha precursor; Interleukin-17A; preinterleukin 1 alpha; pre-interleukin-1 alpha; pro-interleukin-1-alpha; RP23-160G19.8

Gene Symbols:
Il1a

Primary or Secondary:
Primary

Content And Storage:
-20°C

Img

Fischer Scientific

7245548

Rabbit Polyclonal Antibody...


Antigen:
IL-1 alpha

Applications:
ELISA, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P01583

Gene ID (Entrez):
3552

Immunogen:
E.coli-derived Recombinant Human IL-1alpha

Purification Method:
Antigen affinity chromatography

Gene:
Il1a

Concentration:
0.1-1.0 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
PBS with no preservative

Gene Alias:
CTLA8; hematopoietin-1; IL 1 a; IL 1a; IL1; IL-1 alpha; IL17; IL1A; Il-1a; IL-1alpha; IL1-ALPHA; IL1F1; IL1a; ILN; Interleukin; interleukin 1 alpha; interleukin 1, alpha; interleukin 17; interleukin 1a; interleukin 1-alpha; interleukin 1-alpha (AA 1 - 152); Interleukin1 alpha; interleukin-1 alpha; interleukin-1 alpha precursor; Interleukin-17A; preinterleukin 1 alpha; pre-interleukin-1 alpha; pro-interleukin-1-alpha; RP23-160G19.8

Gene Symbols:
Il1a

Primary or Secondary:
Primary

Content And Storage:
-20°C