7245581
CD27 Monoclonal Antibody (O323), Brilliant Ultra Violet™ 615, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD27
Concentration
5 μL/Test
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias
CD antigen 27; CD27; CD27 antigen; CD27 molecule; CD27L receptor; LPFS2; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7
Gene Symbols
CD27
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Clone
O323
Applications
Flow Cytometry
Conjugate
Brilliant Ultraviolet 615
Host Species
Mouse
Target Species
Human
Gene Accession No.
P26842
Gene ID (Entrez)
939
Isotype
IgG1 κ
Purification Method
Affinity chromatography
Gene
CD27
Related Products
Description
- CD27 is a 50 kDa member of the tumor necrosis factor (TNF) receptor superfamily that includes CD40 and CD30
- The TNF superfamily members are known for the regulation of cell proliferation and death
- In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined to lymphocytes
- High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors
- CD70 expression requires additional co-stimulatory and/or pro-inflammatory signals
- CD27 is expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells
- Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid
- Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies
- RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70
- CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor
- Diseases associated with CD27 dysfunction include Lymphoproliferative Syndrome 2 and Autosomal Recessive Lymphoproliferative Syndrome.
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Antigen: CD27
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias: CD antigen 27; CD27; CD27 antigen; CD27 molecule; CD27L receptor; LPFS2; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7
Gene Symbols: CD27
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Clone: O323
Applications: Flow Cytometry
Conjugate: Brilliant Ultraviolet 615
Host Species: Mouse
Target Species: Human
Gene Accession No.: P26842
Gene ID (Entrez): 939
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Gene: CD27
Antigen:
CD27
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
CD antigen 27; CD27; CD27 antigen; CD27 molecule; CD27L receptor; LPFS2; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; TNFSF7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7
Gene Symbols:
CD27
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
O323
Applications:
Flow Cytometry
Conjugate:
Brilliant Ultraviolet 615
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P26842
Gene ID (Entrez):
939
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Gene:
CD27
Antigen: CD45R (B220)
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias: B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Gene Symbols: PTPRC
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Clone: RA3-6B2
Applications: Flow Cytometry
Conjugate: Brilliant Violet 650
Host Species: Rat
Target Species: Human, Mouse
Gene Accession No.: P06800, P08575
Gene ID (Entrez): 19264, 5788
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Gene: PTPRC
Antigen:
CD45R (B220)
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Gene Symbols:
PTPRC
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Clone:
RA3-6B2
Applications:
Flow Cytometry
Conjugate:
Brilliant Violet 650
Host Species:
Rat
Target Species:
Human, Mouse
Gene Accession No.:
P06800, P08575
Gene ID (Entrez):
19264, 5788
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Gene:
PTPRC
Antigen: Factor VIII
Concentration: 0.9 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.4
Gene Alias: AHF; Antihemophilic factor; CF8; Cf-8; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; factor VIII precursor; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7
Gene Symbols: F8
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Clone: F8C-27.4
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P00451
Gene ID (Entrez): 2157
Isotype: IgG2a
Purification Method: Protein G
Gene: F8
Antigen:
Factor VIII
Concentration:
0.9 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.4
Gene Alias:
AHF; Antihemophilic factor; CF8; Cf-8; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; factor VIII precursor; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7
Gene Symbols:
F8
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Clone:
F8C-27.4
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P00451
Gene ID (Entrez):
2157
Isotype:
IgG2a
Purification Method:
Protein G
Gene:
F8
Antigen: Streptococcus Group A
Concentration: 1.56 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with no preservative; pH 7.4
Gene Alias: __
Gene Symbols: __
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Clone: HSA12-340.5
Applications: ELISA
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Isotype: IgG2a
Purification Method: Protein A
Gene: __
Antigen:
Streptococcus Group A
Concentration:
1.56 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with no preservative; pH 7.4
Gene Alias:
__
Gene Symbols:
__
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Clone:
HSA12-340.5
Applications:
ELISA
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Isotype:
IgG2a
Purification Method:
Protein A
Gene:
__