7245719
4-1BB Ligand Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
4-1BB Ligand
Applications
ELISA, Western Blot
Conjugate
Biotin
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P41273
Gene ID (Entrez)
8744
Immunogen
E.coli-derived Recombinant Human 4-1BB Ligand
Purification Method
Antigen affinity chromatography
Gene
TNFSF9
Concentration
0.1-1.0 mg/mL
Classification
Polyclonal
Form
Lyophilized
Regulatory Status
RUO
Formulation
PBS with no preservative
Gene Alias
4 1 BB Ligand; 4 1 BBL; 41BB Ligand; 4-1BB ligand; 41BBL; 4-1BBL; 4-1BB-L; AI848817; CD 137 Ligand; CD 137L; CD137 Ligand; CD137L; Cd157l; CDw137L; costimulatory molecule; homolog of mouse 4-1BB-L; Ly63l; receptor 4-1BB ligand; TNFRSF9; Tnfsf9; TNLG5A; tumor necrosis factor (ligand) superfamily member 9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9
Gene Symbols
TNFSF9
Primary or Secondary
Primary
Content And Storage
-20°C
Related Products
Description
- AA Sequence of recombinant protein: MREGPELSPD DPAGLLDLRQ GMFAQLVAQN VLLIDGPLSW YSDPGLAGVS LTGGLSYKED TKELVVAKAG VYYVFFQLEL RRVVAGEGSG SVSLALHLQP LRSAAGAAAL ALTVDLPPAS SEARNSAFGF QGRLLHLSAG QRLGVHLHTE ARARHAWQLT QGATVLGLFR VTPEIPAGLP SPRSE
- Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human 4-1BB Ligand
- Anti-Human 4-1BB Ligand-specific antibody was purified by affinity chromatography and then biotinylated
- Sandwich ELISA: To detect h4-1BBL by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
- This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human 4-1BBL (500-P169) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant h4-1BBL
- Western Blot: To detect h4-1BBL by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
- Used in conjunction with compatible secondary reagents the detection limit for Recombinant h4-1BBL is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
- 500-P169BT-1MG will be provided as 2 x 500 μg CD137 ligand (CD137L) is a type II membrane protein and part of the TNF superfamily
- CD137L is a co-stimulatory molecule that is expressed on antigen presenting cells (DCs, monocytes/macrophages, B cells) and is upregulated upon activation
- Its receptor, CD137/4-1BB, is found on a variety of cells, including inflamed endothelial cells, where its expression enhances extravasation of CD137L expressing monocytes
- Activated T cells also express CD137, and engagement with CD137L enhances T cell proliferation, IL-2 secretion, survival, and cytotoxic activity
- CD137L is also expressed on a majority of B-cell lymphomas, including mantle cell lymphoma, follicular lymphoma, and diffuse large B-cell lymphoma (but it is lacking on Hodgkin lymphoma and T-cell lymphoma)
- CD137L is also expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interactions.
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Antigen: 4-1BB Ligand
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P41273
Gene ID (Entrez): 8744
Immunogen: E.coli-derived Recombinant Human 4-1BB Ligand
Purification Method: Antigen affinity chromatography
Gene: TNFSF9
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: 4 1 BB Ligand; 4 1 BBL; 41BB Ligand; 4-1BB ligand; 41BBL; 4-1BBL; 4-1BB-L; AI848817; CD 137 Ligand; CD 137L; CD137 Ligand; CD137L; Cd157l; CDw137L; costimulatory molecule; homolog of mouse 4-1BB-L; Ly63l; receptor 4-1BB ligand; TNFRSF9; Tnfsf9; TNLG5A; tumor necrosis factor (ligand) superfamily member 9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9
Gene Symbols: TNFSF9
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
4-1BB Ligand
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P41273
Gene ID (Entrez):
8744
Immunogen:
E.coli-derived Recombinant Human 4-1BB Ligand
Purification Method:
Antigen affinity chromatography
Gene:
TNFSF9
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
4 1 BB Ligand; 4 1 BBL; 41BB Ligand; 4-1BB ligand; 41BBL; 4-1BBL; 4-1BB-L; AI848817; CD 137 Ligand; CD 137L; CD137 Ligand; CD137L; Cd157l; CDw137L; costimulatory molecule; homolog of mouse 4-1BB-L; Ly63l; receptor 4-1BB ligand; TNFRSF9; Tnfsf9; TNLG5A; tumor necrosis factor (ligand) superfamily member 9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9
Gene Symbols:
TNFSF9
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: IL-7
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Rat
Gene Accession No.: P56478
Gene ID (Entrez): 25647
Immunogen: E.coli-derived Recombinant Rat IL-7
Purification Method: Antigen affinity chromatography
Gene: Il7
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: A630026I06Rik; H-IL-7; hlb368; IL7; Il-7; ILN; Interleukin; interleukin 7; Interleukin7; interleukin-7; M-IL-7
Gene Symbols: Il7
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IL-7
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Rat
Gene Accession No.:
P56478
Gene ID (Entrez):
25647
Immunogen:
E.coli-derived Recombinant Rat IL-7
Purification Method:
Antigen affinity chromatography
Gene:
Il7
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
A630026I06Rik; H-IL-7; hlb368; IL7; Il-7; ILN; Interleukin; interleukin 7; Interleukin7; interleukin-7; M-IL-7
Gene Symbols:
Il7
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: IL-7
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Rat
Gene Accession No.: P56478
Gene ID (Entrez): 25647
Immunogen: E.coli-derived Recombinant Rat IL-7
Purification Method: Antigen affinity chromatography
Gene: Il7
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: A630026I06Rik; H-IL-7; hlb368; IL7; Il-7; ILN; Interleukin; interleukin 7; Interleukin7; interleukin-7; M-IL-7
Gene Symbols: Il7
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
IL-7
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Rat
Gene Accession No.:
P56478
Gene ID (Entrez):
25647
Immunogen:
E.coli-derived Recombinant Rat IL-7
Purification Method:
Antigen affinity chromatography
Gene:
Il7
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
A630026I06Rik; H-IL-7; hlb368; IL7; Il-7; ILN; Interleukin; interleukin 7; Interleukin7; interleukin-7; M-IL-7
Gene Symbols:
Il7
Primary or Secondary:
Primary
Content And Storage:
-20°C
Antigen: TNF alpha
Applications: ELISA, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: P06804
Gene ID (Entrez): 21926
Immunogen: E.coli-derived, 17.3 kDa Recombinant Murine TNF-alpha
Purification Method: Antigen affinity chromatography
Gene: Tnf
Concentration: 0.1-1.0 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: PBS with no preservative
Gene Alias: APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Gene Symbols: Tnf
Primary or Secondary: Primary
Content And Storage: -20°C
Antigen:
TNF alpha
Applications:
ELISA, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
P06804
Gene ID (Entrez):
21926
Immunogen:
E.coli-derived, 17.3 kDa Recombinant Murine TNF-alpha
Purification Method:
Antigen affinity chromatography
Gene:
Tnf
Concentration:
0.1-1.0 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
PBS with no preservative
Gene Alias:
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Gene Symbols:
Tnf
Primary or Secondary:
Primary
Content And Storage:
-20°C