74-000-2M20UG

ZO-1 Recombinant Mouse Monoclonal Antibody (ZO1-1A12), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 74-000-2M20UG-Each-of-1 In Stock ₹ 17,026.44

74-000-2M20UG - Each of 1

₹ 17,026.44

In Stock

Quantity

1

Base Price: ₹ 17,026.44

GST (18%): ₹ 3,064.759

Total Price: ₹ 20,091.199

Antigen

ZO-1

Classification

Recombinant Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

P39447, Q07157

Gene Symbols

TJP1

Immunogen

Human recombinant ZO-1 fusion protein encompassing amino acids 334-634

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone

ZO1-1A12

Conjugate

Unconjugated

Gene

TJP1

Gene Alias

DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

21872, 7082

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1 κ

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Description

  • Recombinant mouse monoclonal antibodies are produced using in vitro expression systems
  • Recombinant antibodies are produced using specific genes that code for the desired antibodies
  • These genes are cloned into an expression vector and expressed in vitro
  • The advantages of recombinant antibodies include better specificity and lot-to-lot consistency
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • ZO-1 forms complexes with either ZO-2 or ZO-3
  • In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction
  • ZO-1 expression is significantly reduced in many breast cancer lines
  • ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue
  • ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions
  • ZO-1 may be involved in signal transduction at cell-cell junctions
  • Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene
  • Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.

Compare Similar Items

Show Difference

Img

Fischer Scientific

74-000-2M20UG

--


Antigen:
ZO-1

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P39447, Q07157

Gene Symbols:
TJP1

Immunogen:
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
ZO1-1A12

Conjugate:
Unconjugated

Gene:
TJP1

Gene Alias:
DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
21872, 7082

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Fischer Scientific

74-000-2MP488

--


Antigen:
ZO-1

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Accession No.:
Q07157

Gene Symbols:
TJP1

Immunogen:
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
ZO1-1A12

Conjugate:
Alexa Fluor Plus 488

Gene:
TJP1

Gene Alias:
DKFZp686M05161, I79_005485, MGC133289, OTTHUMP00000174520, Tight junction protein 1, tight junction protein 1 (zona occludens 1), tight junction protein ZO-1, Tjp1, zo1, ZO-1, ZO-1 MDCK, zona occludens 1, zona occludens protein 1, zonula occludens 1, zonula occludens 1 protein, zonula occludens protein 1

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
7082

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Isotype:
IgG1

Img

Fischer Scientific

74-000-2MP555

--


Antigen:
ZO-1

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Accession No.:
Q07157

Gene Symbols:
TJP1

Immunogen:
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
ZO1-1A12

Conjugate:
Alexa Fluor Plus 555

Gene:
TJP1

Gene Alias:
DKFZp686M05161, I79_005485, MGC133289, OTTHUMP00000174520, Tight junction protein 1, tight junction protein 1 (zona occludens 1), tight junction protein ZO-1, Tjp1, zo1, ZO-1, ZO-1 MDCK, zona occludens 1, zona occludens protein 1, zonula occludens 1, zonula occludens 1 protein, zonula occludens protein 1

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
7082

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Isotype:
IgG1

Img

Fischer Scientific

74-000-2MP647

--


Antigen:
ZO-1

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Accession No.:
Q07157

Gene Symbols:
TJP1

Immunogen:
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
ZO1-1A12

Conjugate:
Alexa Fluor Plus 647

Gene:
TJP1

Gene Alias:
DKFZp686M05161, I79_005485, MGC133289, OTTHUMP00000174520, Tight junction protein 1, tight junction protein 1 (zona occludens 1), tight junction protein ZO-1, Tjp1, zo1, ZO-1, ZO-1 MDCK, zona occludens 1, zona occludens protein 1, zonula occludens 1, zonula occludens 1 protein, zonula occludens protein 1

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
7082

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Isotype:
IgG1