74-000-6M

Occludin Recombinant Mouse Monoclonal Antibody (OC-3F10), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 74-000-6M-Each-of-1 In Stock ₹ 34,138.44

74-000-6M - Each of 1

₹ 34,138.44

In Stock

Quantity

1

Base Price: ₹ 34,138.44

GST (18%): ₹ 6,144.919

Total Price: ₹ 40,283.359

Antigen

Occludin

Classification

Recombinant Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

Q16625

Gene Symbols

OCLN

Immunogen

GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Clone

OC-3F10

Conjugate

Unconjugated

Gene

OCLN

Gene Alias

AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

100506658

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1 κ

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Description

  • Recombinant mouse monoclonal antibodies are produced using in vitro expression systems
  • Recombinant antibodies are produced using specific genes that code for the desired antibodies
  • These genes are cloned into an expression vector and expressed in vitro
  • The advantages of recombinant antibodies include better specificity and lot-to-lot consistency
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to approximately 82 kDa
  • Occludin is thought to be involved in regulating both the localization and the function of occludin
  • Polyunsaturated fatty acids are known to up-regulate occludin expression, increasing the transendothelial cell resistance and reducing the cellular permeability to large molecules
  • The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at cell-cell contact sites, whereas non-neural tissues show lower expression and discontinuous distribution
  • Overall structural features of the occludin protein are highly conserved in all the species examined
  • Under-expression of tight junction proteins, including occludin, is a key molecular abnormality responsible for the increased permeability of tumor endothelial tight junctions, which contributes to brain tumor edemas.

Compare Similar Items

Show Difference

Img

Fischer Scientific

74-000-6M

--


Antigen:
Occludin

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q16625

Gene Symbols:
OCLN

Immunogen:
GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
OC-3F10

Conjugate:
Unconjugated

Gene:
OCLN

Gene Alias:
AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100506658

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Fischer Scientific

74-000-6M20UG

--


Antigen:
Occludin

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q16625

Gene Symbols:
OCLN

Immunogen:
GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
OC-3F10

Conjugate:
Unconjugated

Gene:
OCLN

Gene Alias:
AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100506658

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Fischer Scientific

74-000-6MP488

--


Antigen:
Occludin

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Accession No.:
Q16625

Gene Symbols:
OCLN

Immunogen:
GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
OC-3F10

Conjugate:
Alexa Fluor Plus 488

Gene:
OCLN

Gene Alias:
AI503564, BLCPMG, Occludin, occludin 1B, Ocl, Ocln, phosphatase 1, regulatory subunit 115, PPP1R115, tight junction protein occludin, tight junction structural protein

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100506658

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Isotype:
IgG1 κ

Img

Fischer Scientific

74-000-6MP594

--


Antigen:
Occludin

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone, pH 6.5

Gene Accession No.:
Q16625

Gene Symbols:
OCLN

Immunogen:
GST fusion protein consisting of the C-terminal region (∽150aa) of human occludin.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
OC-3F10

Conjugate:
Alexa Fluor Plus 594

Gene:
OCLN

Gene Alias:
AI503564, BLCPMG, Occludin, occludin 1B, Ocl, Ocln, phosphatase 1, regulatory subunit 115, PPP1R115, tight junction protein occludin, tight junction structural protein

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100506658

Content And Storage:
4°, C, store in dark, DO NOT FREEZE!

Isotype:
IgG1 κ