74-000-9M
CD28 Recombinant Mouse Monoclonal Antibody (CD28.2), Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 74-000-9M-Each-of-1 | In Stock | ₹ 25,668.00 |
74-000-9M - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,668.00
GST (18%): ₹ 4,620.24
Total Price: ₹ 30,288.24
Antigen
CD28
Classification
Recombinant Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.
P10747
Gene Symbols
Cd28
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
940
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry
Clone
CD28.2
Conjugate
Unconjugated
Gene
Cd28
Gene Alias
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Recombinant antibodies are produced using specific genes that code for the desired antibodies
- These genes are cloned into an expression vector and expressed in vitro
- The advantages of recombinant antibodies include better specificity and lot-to-lot consistency
- Description: The CD28.2 recombinant mouse monoclonal antibody reacts with the human CD28 molecule, a 44 kDa homodimer expressed by thymocytes, mature T cells and plasma cells
- CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) and is a potent co-stimulator of T cells
- Signaling through CD28 augments IL-2 and IL-2 receptor expression as well as cytotoxicity of CD3-activated T cells
- Applications Reported: The CD28.2 recombinant mouse monoclonal antibody has been reported for use in flow cytometric analysis
- CD28.2 has also been reported in costimulation of T cells in in vitro functional assays
- Applications Tested: The CD28.2 recombinant mouse monoclonal antibody has been tested by flow cytometric analysis of normal human peripheral blood cells
- This can be used at 0.025 μg/test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Filtration: 0.2 μm post-manufacturing filtered
- CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein
- CD28 is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes
- Moreover, CD28 is the critical T cell costimulatory receptor that provides the cell the important second activation signal by binding CD80 and CD86 which are expressed by antigen presenting cells
- In addition to its co-stimulation role, CD28 functions by preventing T cells from entering an anergic-hyporesponsive state or from undergoing premature apoptotic cell death
- In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28
- In the thymus, CD28 expression is highest on immature CD3-, CD8+ and CD4+8+ cells, and on CD4-8- cells that express alpha/beta and gamma/delta TCR
- The level of CD28 on mature CD4+ and CD8+ alpha/beta TCR+ thymocytes is two- to fourfold lower than on the immature cells
- Diseases associated with CD28 dysfunction include mycosis fungiodes and Sezary's Disease.
Compare Similar Items
Show Difference
Antigen: CD28
Classification: Recombinant Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: P10747
Gene Symbols: Cd28
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 940
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry
Clone: CD28.2
Conjugate: Unconjugated
Gene: Cd28
Gene Alias: antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD28
Classification:
Recombinant Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
P10747
Gene Symbols:
Cd28
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
940
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry
Clone:
CD28.2
Conjugate:
Unconjugated
Gene:
Cd28
Gene Alias:
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD28
Classification: Recombinant Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: P10747
Gene Symbols: Cd28
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 940
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry
Clone: CD28.2
Conjugate: Unconjugated
Gene: Cd28
Gene Alias: antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species: Mouse
Quantity: 20 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD28
Classification:
Recombinant Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
P10747
Gene Symbols:
Cd28
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
940
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry
Clone:
CD28.2
Conjugate:
Unconjugated
Gene:
Cd28
Gene Alias:
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species:
Mouse
Quantity:
20 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD28
Classification: Recombinant Monoclonal
Concentration: 1.0 mg/mL
Formulation: proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone; pH 6.5
Gene Accession No.: P10747
Gene Symbols: Cd28
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 940
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: CD28.2
Conjugate: Alexa Fluor Plus 488
Gene: Cd28
Gene Alias: antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species: Mouse
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: __
Isotype: IgG1 κ
Antigen:
CD28
Classification:
Recombinant Monoclonal
Concentration:
1.0 mg/mL
Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone; pH 6.5
Gene Accession No.:
P10747
Gene Symbols:
Cd28
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
940
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
CD28.2
Conjugate:
Alexa Fluor Plus 488
Gene:
Cd28
Gene Alias:
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species:
Mouse
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
__
Isotype:
IgG1 κ
Antigen: CD28
Classification: Recombinant Monoclonal
Concentration: 1.0 mg/mL
Formulation: proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone; pH 6.5
Gene Accession No.: P10747
Gene Symbols: Cd28
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 940
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: CD28.2
Conjugate: Alexa Fluor Plus 555
Gene: Cd28
Gene Alias: antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species: Mouse
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: __
Isotype: IgG1 κ
Antigen:
CD28
Classification:
Recombinant Monoclonal
Concentration:
1.0 mg/mL
Formulation:
proprietary buffer with 0.008% Bromonitrodioxane, 0.008% Methylisothiazolone; pH 6.5
Gene Accession No.:
P10747
Gene Symbols:
Cd28
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
940
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
CD28.2
Conjugate:
Alexa Fluor Plus 555
Gene:
Cd28
Gene Alias:
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species:
Mouse
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
__
Isotype:
IgG1 κ