89-110-866

BRCA1 Mouse anti-Human, Monoclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-110-866-Each-of-1 In Stock ₹ 1,00,704.12

89-110-866 - Each of 1

₹ 1,00,704.12

In Stock

Quantity

1

Base Price: ₹ 1,00,704.12

GST (18%): ₹ 18,126.742

Total Price: ₹ 1,18,830.862

Antigen

BRCA1

Classification

Monoclonal

Description

Mouse monoclonal antibody raised against partial recombinant BRCA1.

Formulation

In PBS, pH 7.4

Gene Alias

BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein.

Content And Storage

Store at -80°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1 κ

Applications

Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1-10 ug/mL) Immunoprecipitation (1-10 ug/mL) The optimal working dilution should be determined by the end user.

Gene

BRCA1

Gene Symbols

BRCA1

Immunogen

Recombinant GST fusion protein corresponding to amino acids 341-748 of BRCA1.

Regulatory Status

RUO

Gene ID (Entrez)

672

Target Species

Human

Form

Liquid

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Description

  • This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor
  • The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC)
  • This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes
  • This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination
  • Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers
  • Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene
  • Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described
  • A related pseudogene, which is also located on chromosome 17, has been identified
  • [provided by RefSeq

Compare Similar Items

Show Difference

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Abnova Corporation

89-110-866

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Antigen:
BRCA1

Classification:
Monoclonal

Description:
Mouse monoclonal antibody raised against partial recombinant BRCA1.

Formulation:
In PBS, pH 7.4

Gene Alias:
BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein.

Content And Storage:
Store at -80°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1 κ

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1-10 ug/mL) Immunoprecipitation (1-10 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
BRCA1

Gene Symbols:
BRCA1

Immunogen:
Recombinant GST fusion protein corresponding to amino acids 341-748 of BRCA1.

Regulatory Status:
RUO

Gene ID (Entrez):
672

Target Species:
Human

Form:
Liquid

Img

Abnova Corporation

89-110-869

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Antigen:
F8

Classification:
Monoclonal

Description:
Mouse monoclonal antibody raised against native F8.

Formulation:
In PBS, pH 7.4

Gene Alias:
AHF/DXS1253E/F8B/F8C/FVIII/HEMA

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Recognize full-length human Factor VIII.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Applications:
ELISA

Conjugate:
Unconjugated

Dilution:
ELISA (1:32000) The optimal working dilution should be determined by the end user.

Gene:
F8

Gene Symbols:
F8

Immunogen:
Native purified human F8.

Regulatory Status:
RUO

Gene ID (Entrez):
2157

Target Species:
Human

Form:
Liquid

Img

Abnova Corporation

89-110-870

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Antigen:
F8

Classification:
Monoclonal

Description:
Mouse monoclonal antibody raised against native F8.

Formulation:
In PBS, pH 7.4

Gene Alias:
AHF/DXS1253E/F8B/F8C/FVIII/HEMA

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Recognize full-length human Factor VIII.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Applications:
ELISA

Conjugate:
Unconjugated

Dilution:
ELISA (1:32000) The optimal working dilution should be determined by the end user.

Gene:
F8

Gene Symbols:
F8

Immunogen:
Native purified human F8.

Regulatory Status:
RUO

Gene ID (Entrez):
2157

Target Species:
Human

Form:
Liquid

Img

Abnova Corporation

89-110-871

--


Antigen:
F8

Classification:
Monoclonal

Description:
Mouse monoclonal antibody raised against native F8.

Formulation:
In PBS, pH 7.4

Gene Alias:
AHF/DXS1253E/F8B/F8C/FVIII/HEMA

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Recognize full-length human Factor VIII.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype:
IgG1

Applications:
ELISA

Conjugate:
Unconjugated

Dilution:
ELISA (1:16000) The optimal working dilution should be determined by the end user.

Gene:
F8

Gene Symbols:
F8

Immunogen:
Native purified human F8.

Regulatory Status:
RUO

Gene ID (Entrez):
2157

Target Species:
Human

Form:
Liquid