89-110-963

BRCA1, Mouse, Clone: MU, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-110-963-Each-of-1 In Stock ₹ 83,677.68

89-110-963 - Each of 1

₹ 83,677.68

In Stock

Quantity

1

Base Price: ₹ 83,677.68

GST (18%): ₹ 15,061.982

Total Price: ₹ 98,739.662

Antigen

BRCA1

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Western Blot (2-4 ug/mL) The optimal working dilution should be determined by the end user.

Gene

BRCA1

Gene Symbols

BRCA1

Immunogen

Recombinant protein corresponding to amino acids 1314-1864 of human BRCA1.

Regulatory Status

RUO

Gene ID (Entrez)

672

Target Species

Human

Form

Liquid

Applications

Immunofluorescence, Immunoprecipitation, Western Blot

Clone

MU

Description

Mouse monoclonal antibody raised against partial recombinant BRCA1.

Formulation

In buffer containing 0.05% sodium azide

Gene Alias

BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Test Specificity

This antibody recognizes the epitope aa 1600-1749.

Content And Storage

Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor
  • The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC)
  • This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes
  • This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination
  • Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers
  • Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene
  • Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described
  • A related pseudogene, which is also located on chromosome 17, has been identified
  • [provided by RefSeq

Compare Similar Items

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Abnova Corporation

89-110-963

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Antigen:
BRCA1

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (2-4 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
BRCA1

Gene Symbols:
BRCA1

Immunogen:
Recombinant protein corresponding to amino acids 1314-1864 of human BRCA1.

Regulatory Status:
RUO

Gene ID (Entrez):
672

Target Species:
Human

Form:
Liquid

Applications:
Immunofluorescence, Immunoprecipitation, Western Blot

Clone:
MU

Description:
Mouse monoclonal antibody raised against partial recombinant BRCA1.

Formulation:
In buffer containing 0.05% sodium azide

Gene Alias:
BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes the epitope aa 1600-1749.

Content And Storage:
Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.

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Abnova Corporation

89-110-967

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Antigen:
ARNT

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.

Gene:
ARNT

Gene Symbols:
ARNT

Immunogen:
Recombinant protein corresponding to amino acids 496-789 of human ARNT.

Regulatory Status:
RUO

Gene ID (Entrez):
405

Target Species:
Bovine, Ferret, Human, Mouse, Rat, Sheep

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Clone:
H1beta234

Description:
Mouse monoclonal antibody raised against partial recombinant ARNT.

Formulation:
In PBS (0.05% sodium azide)

Gene Alias:
HIF-1beta/HIF1B/HIF1BETA/TANGO/bHLHe2

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
This antibody is specific to HIF-1 beta /ARNT.

Content And Storage:
Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-110-968

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Antigen:
APOE

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (2 ug/mL) Immunohistochemistry (2 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
APOE

Gene Symbols:
APOE

Immunogen:
Human APOE.

Regulatory Status:
RUO

Gene ID (Entrez):
348

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
WUE-4

Description:
Mouse monoclonal antibody raised against APOE.

Formulation:
In Tris-glycine, 150mM NaCl (0.05% sodium azide)

Gene Alias:
AD2/LPG/MGC1571/apoprotein

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C for short term. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-110-969

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Antigen:
APEX1

Classification:
Monoclonal

Conjugate:
Unconjugated

Dilution:
Immunocytochemistry (1:50-1:200) Immunofluorescence (1:50-1:200) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) The optimal working dilution should be determined by the end user.

Gene:
APEX1

Gene Symbols:
APEX1

Immunogen:
Human APEX1.

Regulatory Status:
RUO

Gene ID (Entrez):
328

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
13B8E5C2

Description:
Mouse monoclonal antibody raised against APEX1.

Formulation:
In PBS (0.05% sodium azide)

Gene Alias:
APE/APE-1/APE1/APEN/APEX/APX/HAP1/REF-1/REF1

Host Species:
Mouse

Quantity:
50 μL

Primary or Secondary:
Primary

Test Specificity:
This antibody is specific to the human APE/ref-1 protein.

Content And Storage:
Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.