89-114-761

RELA Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-114-761-Each-of-1 In Stock ₹ 1,00,618.56

89-114-761 - Each of 1

₹ 1,00,618.56

In Stock

Quantity

1

Base Price: ₹ 1,00,618.56

GST (18%): ₹ 18,111.341

Total Price: ₹ 1,18,729.901

Antigen

RELA

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of RELA.

Formulation

In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide)

Gene Alias

MGC131774/NFKB3/p65

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

The epitope recognized overlaps the NLS of the p65 subunit of the NFkB heterodimer. Therefore, This antibody selectively binds to the activated form of NFkB.

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

ELISA, Gel Shift, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1:2000) Gel Supershift Assay (0.5-1.0 ul per assay) Immunohistochemistry (1:200) Immunofluorescence (1:200) The optimal working dilution should be determined by the end user.

Gene

RELA

Gene Symbols

RELA

Immunogen

A synthetic peptide (conjugated with KLH) corresponding to N-terminus end of human RELA.

Regulatory Status

RUO

Gene ID (Entrez)

5970

Target Species

Human

Form

Liquid

Description

  • NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex
  • The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB
  • The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm
  • Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex
  • Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM

Compare Similar Items

Show Difference

Img

Abnova Corporation

89-114-761

--


Antigen:
RELA

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of RELA.

Formulation:
In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide)

Gene Alias:
MGC131774/NFKB3/p65

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
The epitope recognized overlaps the NLS of the p65 subunit of the NFkB heterodimer. Therefore, This antibody selectively binds to the activated form of NFkB.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Gel Shift, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1:2000) Gel Supershift Assay (0.5-1.0 ul per assay) Immunohistochemistry (1:200) Immunofluorescence (1:200) The optimal working dilution should be determined by the end user.

Gene:
RELA

Gene Symbols:
RELA

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to N-terminus end of human RELA.

Regulatory Status:
RUO

Gene ID (Entrez):
5970

Target Species:
Human

Form:
Liquid

Img

Abnova Corporation

89-114-762

--


Antigen:
NOTCH1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of NOTCH1.

Formulation:
In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.1% sodium azide)

Gene Alias:
TAN1/hN1

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Test Specificity:
This antiserum is directed against human NOTCH 1. Only the cleaved intracellular (activated) form (NICD) is detected. No reactivity is detected against mouse N2, N3 or N4. The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved form.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Dilution:
Sandwich ELISA (1:20000-1:60000) Western Blot (1:500) The optimal working dilution should be determined by the end user.

Gene:
NOTCH1

Gene Symbols:
NOTCH1

Immunogen:
A synthetic peptide corresponding to N-terminus the cleaved N intracellular domain (NICD) of human NOTCH1.

Regulatory Status:
RUO

Gene ID (Entrez):
4851

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Abnova Corporation

89-114-763

--


Antigen:
NOTCH1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of NOTCH1.

Formulation:
In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide)

Gene Alias:
TAN1/hN1

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Test Specificity:
This antiserum is directed against human NOTCH 1. No reaction is detected against NOTCH 2. No reactivity was observed against Mouse Notch.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
ELISA (1:20000-1:100000) Western Blot (1:2000-1:10000) Immunohistochemistry (1:1000-1:5000) The optimal working dilution should be determined by the end user.

Gene:
NOTCH1

Gene Symbols:
NOTCH1

Immunogen:
A synthetic peptide corresponding to amino acids 2488-2502 of human NOTCH1.

Regulatory Status:
RUO

Gene ID (Entrez):
4851

Target Species:
Human

Form:
Liquid

Img

Abnova Corporation

89-114-767

--


Antigen:
POU5F1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of POU5F1.

Formulation:
In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide)

Gene Alias:
MGC22487/OCT3/OCT4/OTF3/OTF4

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This antibody reacts with human and mouse Oct-4 protein.

Content And Storage:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications:
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Dilution:
ELISA (1:350000) Western Blot (1:1000-1:1500) The optimal working dilution should be determined by the end user.

Gene:
POU5F1

Gene Symbols:
POU5F1

Immunogen:
A synthetic peptide corresponding to internal region of human POU5F1.

Regulatory Status:
RUO

Gene ID (Entrez):
5460

Target Species:
Human

Form:
Liquid