89-115-677

ERBB3 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-115-677-Each-of-1 In Stock ₹ 51,079.32

89-115-677 - Each of 1

₹ 51,079.32

In Stock

Quantity

1

Base Price: ₹ 51,079.32

GST (18%): ₹ 9,194.278

Total Price: ₹ 60,273.598

Antigen

ERBB3

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.

Gene

ERBB3

Gene Alias

ErbB-3/HER3/LCCS2/MDA-BF-1/MGC88033/c-erbB-3/c-erbB3/erbB3-S/p180-ErbB3/p45-sErbB3/p85-sErbB3

Host Species

Rabbit

Purification Method

Immunoaffinity purification

Regulatory Status

RUO

Gene ID (Entrez)

2065

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Concentration

1 mg/mL

Description

Rabbit polyclonal antibody raised against synthetic peptide of ERBB3.

Formulation

In PBS (without mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.

P21860

Gene Symbols

ERBB3

Immunogen

A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y1328 of human ERBB3.

Quantity

100 μL

Primary or Secondary

Primary

Test Specificity

Her3/ErbB3 (Ab-1328) Antibody detects endogenous levels of total Her3/ErbB3 protein.

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Description

  • This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases
  • This membrane-bound protein has a neuregulin binding domain but not an active kinase domain
  • It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation
  • However, it does form heterodimers with other EGF receptor family members which do have kinase activity
  • Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation
  • Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors
  • Alternate transcriptional splice variants encoding different isoforms have been characterized
  • One isoform lacks the intermembrane region and is secreted outside the cell
  • This form acts to modulate the activity of the membrane-bound form
  • Additional splice variants have also been reported, but they have not been thoroughly characterized
  • [provided by RefSeq Sequence: PDYWH

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Abnova Corporation

89-115-677

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Antigen:
ERBB3

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.

Gene:
ERBB3

Gene Alias:
ErbB-3/HER3/LCCS2/MDA-BF-1/MGC88033/c-erbB-3/c-erbB3/erbB3-S/p180-ErbB3/p45-sErbB3/p85-sErbB3

Host Species:
Rabbit

Purification Method:
Immunoaffinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
2065

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic peptide of ERBB3.

Formulation:
In PBS (without mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.:
P21860

Gene Symbols:
ERBB3

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y1328 of human ERBB3.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
Her3/ErbB3 (Ab-1328) Antibody detects endogenous levels of total Her3/ErbB3 protein.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-115-679

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Antigen:
MET

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.

Gene:
MET

Gene Alias:
AUTS9/HGFR/RCCP2/c-Met

Host Species:
Rabbit

Purification Method:
Immunoaffinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
4233

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed)

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic peptide of MET.

Formulation:
In PBS (without Mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.:
__

Gene Symbols:
MET

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y1003 of human MET.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
Met (Ab-1003) Antibody detects endogenous levels of total Met protein.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-115-680

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Antigen:
EIF4B

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.

Gene:
EIF4B

Gene Alias:
EIF-4B/PRO1843

Host Species:
Rabbit

Purification Method:
Immunoaffinity purification

Regulatory Status:
RUO

Gene ID (Entrez):
1975

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed)

Concentration:
1 mg/mL

Description:
Rabbit polyclonal antibody raised against synthetic peptide of EIF4B.

Formulation:
In PBS (without mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.:
P23588

Gene Symbols:
EIF4B

Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S422 of human EIF4B.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
eIF4B (Ab-422) Antibody detects endogenous levels of total Her3/ErbB3 protein

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-115-682

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Antigen:
BRCA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Dilution:
Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.

Gene:
BRCA1

Gene Alias:
BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
672

Target Species:
Human

Form:
Liquid

Applications:
Immunofluorescence

Concentration:
__

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRCA1.

Formulation:
In PBS (without mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.:
P38398

Gene Symbols:
BRCA1

Immunogen:
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S988 of human BRCA1.

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
BRCA1 (phospho-Ser988) antibody detects endogenous levels of BRCA1 only when phosphorylated at serine 988.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.