89-115-682

BRCA1 (phospho S988), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

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Pack Size SKU Availability Price
Each of 1 89-115-682-Each-of-1 In Stock ₹ 54,929.52

89-115-682 - Each of 1

₹ 54,929.52

In Stock

Quantity

1

Base Price: ₹ 54,929.52

GST (18%): ₹ 9,887.314

Total Price: ₹ 64,816.834

Antigen

BRCA1

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRCA1.

Formulation

In PBS (without mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.

P38398

Gene Symbols

BRCA1

Immunogen

Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S988 of human BRCA1.

Regulatory Status

RUO

Gene ID (Entrez)

672

Target Species

Human

Form

Liquid

Applications

Immunofluorescence

Conjugate

Unconjugated

Dilution

Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.

Gene

BRCA1

Gene Alias

BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Test Specificity

BRCA1 (phospho-Ser988) antibody detects endogenous levels of BRCA1 only when phosphorylated at serine 988.

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor
  • The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC)
  • This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes
  • This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination
  • Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers
  • Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene
  • Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described
  • A related pseudogene, which is also located on chromosome 17, has been identified
  • [provided by RefSeq Sequence: IKSpFV

Compare Similar Items

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Img

Abnova Corporation

89-115-682

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Antigen:
BRCA1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRCA1.

Formulation:
In PBS (without mg2+and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.:
P38398

Gene Symbols:
BRCA1

Immunogen:
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S988 of human BRCA1.

Regulatory Status:
RUO

Gene ID (Entrez):
672

Target Species:
Human

Form:
Liquid

Applications:
Immunofluorescence

Conjugate:
Unconjugated

Dilution:
Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.

Gene:
BRCA1

Gene Alias:
BRCAI/BRCC1/IRIS/PSCP/RNF53

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
BRCA1 (phospho-Ser988) antibody detects endogenous levels of BRCA1 only when phosphorylated at serine 988.

Content And Storage:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Abnova Corporation

89-115-684

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Antigen:
CCR6

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of CCR6.

Formulation:
Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4(5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)

Gene Accession No.:
__

Gene Symbols:
CCR6

Immunogen:
A synthetic peptide corresponding to amino acids at N-terminus of human CCR6.

Regulatory Status:
RUO

Gene ID (Entrez):
1235

Target Species:
Human, Mouse, Rat

Form:
Lyophilized

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (0.75 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
CCR6

Gene Alias:
BN-1/CD196/CKR-L3/CKR6/CKRL3/CMKBR6/DCR2/DRY-6/GPR-CY4/GPR29/GPRCY4/STRL22

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Identical to the related rat and mouse sequence.

Content And Storage:
Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water and concentration will be 500μ/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Img

Abnova Corporation

89-115-688

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Antigen:
ANGPT2

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of ANGPT2.

Formulation:
Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4(5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)

Gene Accession No.:
AB009865

Gene Symbols:
ANGPT2

Immunogen:
A synthetic peptide corresponding to amino acids at C-terminus of human ANGPT2.

Regulatory Status:
RUO

Gene ID (Entrez):
285

Target Species:
Human, Rat

Form:
Lyophilized

Applications:
Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL) The optimal working dilution should be determined by the end user.

Gene:
ANGPT2

Gene Alias:
AGPT2/ANG2

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Different from the related mouse sequence by two amino acids.

Content And Storage:
Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water and concentration will be 500μ/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Abnova Corporation

89-115-690

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Antigen:
LMNB1

Classification:
Polyclonal

Description:
Rabbit polyclonal antibody raised against synthetic peptide of LMNB1.

Formulation:
Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4(5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)

Gene Accession No.:
BC012295

Gene Symbols:
LMNB1

Immunogen:
A synthetic peptide corresponding to amino acids at C-terminus of human LMNB1.

Regulatory Status:
RUO

Gene ID (Entrez):
4001

Target Species:
Human, Mouse, Rat

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Western Blot

Conjugate:
Unconjugated

Dilution:
Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Immunohistochemistry (Frozen sections) (0.5-1 ug/mL) Immunocytochemistry (0.5-1 ug/mL) The optimal working dilution should be determine

Gene:
LMNB1

Gene Alias:
ADLD/LMN/LMN2/LMNB/MGC111419

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Different from the related rat and mouse sequence by three amino acids.

Content And Storage:
Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water to a concentration of 500μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.